New AABB Guidelines for Red Blood Cell Storage and Transfusion Thresholds
October 13, 2016
The AABB has recently published updated guidelines for red blood cell (RBC) transfusion thresholds and the optimal length of storage. Based on a comprehensive systematic review and meta-analysis incorporating 31 randomized controlled trials, the AABB strongly recommends a restrictive hemoglobin transfusion threshold… [Read More]
Prothrombin Complex Concentrates are Superior to Fresh Frozen Plasma for Urgent Warfarin Reversal
October 6, 2016
Although warfarin is a common anticoagulant used to prevent blood clots and strokes, it is associated with major bleeding episodes that occasionally need to be stopped quickly. Urgent surgery patients who are taking warfarin to be reversed quickly, which is accomplished by either (1) transfusing fresh frozen plasma… [Read More]
New Techniques Identify Oxidative Lesions on Stored RBCs
September 28, 2016
Stored red blood cells (RBCs) undergo morphologic and biochemical changes with time. In a recently published study in Blood, researchers used a novel, multi-pronged approach in order to gain a better understanding of storage lesions for RBCs stored in AS-3 (a common storage solution). [Read More]
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