The nice people at Wesgard QC sent their update today. You can read it by clicking here. I did. I’d suggest you do to, but I’ve got a degree in maths and I found it heavy going.
27 May 2026 (Wednesday) - Westgard QC Update
The nice people at Wesgard QC sent their update today. You can read it by clicking here. I did. I’d suggest you do to, but I’ve got a degree in maths and I found it heavy going.
27 May 2026 (Wednesday) - BTLP-TACT Exercise
37192 – a twenty-one year-old woman in maternity needing group and saveHer ABO group was indeterminate, but she was Rh(D) Positive with a negative antibody screen46614 – a ninety-six year-ol d chap needing four untits of FFP for bleeding varices.He grouped as O Rh(D) Positive with antibody screen positive on cells 1 & 3. I performed antibody panels.The enzyme panel was negative throughout. The IAT panel was positive in cells 1, 3, 6, 9 and 10 corresponding with anti-Fy(a)FFP is NOT recommended for bleeding varices https://pubmed.ncbi.nlm.nih.gov/33969607/ so I didn’t issue any
22 May 2026 (Friday) - UKAS Update
The nice people at UKAS sent their
update today. You can read it by
clicking here. I always do as I struggle to understand exactly what UKAS
actually does, and how what it does is relevant to my daily round.
One thing they do is to charge various
employers for their services… and it would seem that some of that money has
been spent on buying
three hundred and fifty trees which have been planted by UKAS staff who’ve
been given a day’s leave to do so.
I’m even more mystified…
22 May 2026 (Friday) - BTLP-TACT Exercise
21 May 2026 (Thursday) - Transfusion Evidence Library Update
The nice people at the Transfusion
Evidence Library sent their update today. As always there was too much to take
in at one sitting:
ARTICLE OF THE MONTH
Intravenous ferric carboxymaltose versus oral ferrous sulphate for the treatment of moderate-to-severe postpartum anaemia in Nigerian women (IVON-PP): an open-label, randomised controlled trial.
Afolabi, B.B., et al. (2026). The Lancet. Global Health.
PICO SUMMARY
TOP ARTICLES
Angio-Seal plug-based versus dual ProGlide for transfemoral hemostasis in transcatheter aortic valve replacement: a systematic review and meta-analysis.
Alnomani, Y.R., et al. (2026). Journal of Thrombosis and Thrombolysis. [Record in progress].
Low-dose vs. standard care Iv human albumin during large-volume paracentesis in patients with liver cirrhosis: a systematic review.
Bot, K., et al. (2026). Liver International.
The efficacy of interactive communication interventions for motivating blood donation: a systematic review.
Boult, L., et al. (2026). Vox Sanguinis. [Record in progress].
Red blood cell transfusion in neurocritical patients: an updated systematic review and meta-analysis.
Fu, Y., et al. (2026). BMC Anesthesiology.
Effect of donor exclusion criteria on blood safety and volume of donations: a systematic review of modelling studies.
Mosselmans, L., et al. (2026). Bulletin of the World Health Organization.
Blood donation and subjective wellbeing: a cross-sectional survey and a randomized trial.
Ou-Yang, J., et al. (2026). Frontiers in Psychology.
Therapeutic plasma exchange improves short-term survival in patients with acute-on-chronic liver failure: a randomized controlled trial.
Swaroop, S., et al. (2026). Hepatology. [Record in progress].
The effect of stress ball and music on anxiety, distress, and pain levels during platelet apheresis donation: randomized controlled trial.
Urtekin, D., et al. (2026). Transfusion Medicine Reviews. [Record in progress].
18 May 2026 (Monday) - BTLP-TACT Exercise
15 May 2026 (Friday) - Religion (!)
15 May 2026 (Friday) - Horiba Update
11 May 2026 (Monday) - BTLP-TACT Exercise
44156 – a forty-two year-old woman with liver disease and bleeding needing four units of FFP.The control well failed so the group was uninterpretable.The antibody screen was negative.I issued two units of AB FFP as there was only two units there.34387 – an eighty-four year-old chap in A&E also with liver disease just requiring group and save.He grouped as O Rh(D) Negative with antibody screen positive in wells 1 & 3 so I performed antibody panels.The enzyme panel was negative throughout.The IAT panel was positive in cells 1, 3, 4, 6, 8 and 10 corresponding with anti- s but not excluding anti-Kp(a)
I got the green light.
11 May 2026 (Monday) - Iffy Valves
8 May 2026 (Friday) - BTLP-TACT Exercise
93449 – a sixty-nine year-old chap with sickle cell disease needing two units of bloodHe grouped as O Rh(D) Positive with a negative antibody screen.I selected two units of O Rh(D) Positive.62030 – a sixty-eight year-old chap needing group and save for a fem-pop bypass.He grouped as A Rh(D) Positive also with a negative antibody screen.
7 May 2026 (Thursday) - Horiba Update
5 May 2026 (Tuesday) - Transfusion Evidence Library Update
The nice people at the Transfusion
Evidence Library sent their update today. As always it boggled my poor brain.
It was a lot to take in…
ARTICLE OF THE MONTH
Prehospital whole blood in traumatic hemorrhage - a randomized controlled trial.
Smith, J.E., et al. (2026). The New England Journal of Medicine. [Record in progress].
PICO SUMMARY
TOP ARTICLES
Romiplostim versus placebo for chemotherapy-induced thrombocytopenia.
Al-Samkari, H., et al. (2026). The New England Journal of Medicine.
Impact of feeding strategies during red blood cell transfusion on cerebral and splanchnic oxygenation in preterm infants: randomized pilot study.
Aslan Tuncay, S., et al. (2026). Journal of Neonatal-Perinatal Medicine. [Record in progress].
Erythropoiesis-stimulating agents to reduce heart failure hospitalization: a systematic review and meta-analysis.
Bunting, K.V., et al. (2026). European Journal of Heart Failure.
Substantial international variation in the cost of blood group and save and crossmatch: a systematic review.
Fabiano, G., et al. (2026). British Journal of Haematology.
Statistically significant results favored in abstracts of platelet rich plasma treatment of knee osteoarthritis: a systematic review and spin analysis.
Fullano, G.D., et al. (2026). Arthroscopy.
Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis.
Kimber, C., et al. (2026). BMC Neurology.
Blood donation practices and behavioral intentions: a scoping review using the theory of planned behavior.
Lakew, G., et al. (2026). PLoS One.
Prophylactic haemostatic treatment to control iatrogenic bleeding during endobronchial biopsy (PROTECT study): a multicentre, randomised, single-blind, placebo-controlled study.
Li, B., et al. (2026). Chest. [Record in progress].
Artificial intelligence implementation in transfusion medicine: addressing the challenges of clinical adoption.
Maynard, S., et al. (2026). Transfusion Medicine Reviews.
Albumin replacement therapy in septic shock: a randomized clinical trial.
Sakr, Y., et al. (2026). JAMA Network Open.
3 May 2026 (Sunday) - Babeosis
Apparently severe cases are treated with exchange transfusions
Forewarned is forearmed…
3 May 2026 (Sunday) - Slide Saturday Challenge
Flame cells… I don’t think I’ve ever actually seen them in real life…
2 May 2026 (Saturday) - Unexpected Thrombocytosis
1 May 2026 (Friday) - HCPC Update
The HCPC sent out their newsletter today. You can read
it by clicking here. As always I wish it was of more direct relevance to me…
30 April 2026 (Thursday) - BTLP-TACT Exercise
28 April 2026 (Tuesday) - Westgard QC Update
The nice people at Westgard QC sent their update today. It was rather heavy going, but statistical stuff often is.
21 April 2026 (Tuesday) - BTLP-TACT
20 April 2026 (Monday) - UKAS Update
20 April 2026 (Monday) - NEQAS 2505DM
19 April 2026 (Sunday) - I Got That Wrong...
I won’t lie… I thought it was hairy cell leukaemia. They do look similar, but are very different diseases. Flow cytometry comes into play… as the article says.
14 April 2026 (Tuesday) - BTLP-TACT Exercise
78080 – a thirty year old woman in the haematology clinic needing two units of irradiated blood.The sample label had no NHS number or hospital number so I rejected it.33345 – an eighty-nine year old chap in out-patients needing group and save.He grouped as O Rh(D) Negative with antibody screen positive in cells 1 and 2. I performed antibody panels.The enzyme and IAT panels were positive in cells 1, 2, 3 and 4 corresponding with anti-C and anti-D but not excluding anti-Cw
12 April 2026 (Sunday) - A Giant Platelet
Here’s a few words about Bernard-Soulier syndrome.























