28 February 2022 (Monday) - BTLP-TACT Excercise

Time for another BTLP-TACT exercise…
I was presented with two cases from the out-patients department.

51855 – a sixty-one year-old chap with iron deficiency anaemia (and previous transfusions) requiring group & save.He grouped as B Rh(D) Positive with a negative antibody screen

34060 – a thirty-four year-old chap requiring two units of irradiated blood within two hours.
He grouped as A Rh(D) Negative also with a negative antibody screen

I selected two A Rh(D) Negative K-negative irradiated units 

I got the green light, which is always something of a relief.

28 February 2022 (Monday) - Transfusion Evidence Alert Update


The nice people at the “Transfusion Evidence Alert” sent their update today. As always there was far too much to take in at one go, but it only comes out monthly…
The first article on transfusion thresholds was interesting… when should you give a transfusion… opinion varies so much, and has done so over the years…



Transfusion thresholds for guiding red blood cell transfusion.Carson, J.L., et al. (2021). The Cochrane Database of Systematic Reviews.PICO Summary available



Confirmation Bias Affects Estimation of Blood Loss and Amniotic Fluid Volume: A Randomized Simulation-Based Trial.Atallah, F., et al. (2021). American Journal of Perinatology.

Efficacy and Safety of Intravenous Iron Therapy for Treating Anaemia in Critically ill Adults: A Rapid Systematic Review With Meta-Analysis.Geneen, L.J., et al. (2021). Transfusion Medicine Reviews. [Record in progress]

Red blood cell transfusion in myelodysplastic syndromes: A systematic review.Kaka, S., et al. (2021). Transfusion Medicine.

Preemptive antifibrinolysis: its role and efficacy in hip-fracture patients undergoing total hip arthroplasty.Liu, J., et al. (2021). The Journal of Arthroplasty. [Record in progress]

Tranexamic Acid for Prevention of Hemorrhage in Elective Repeat Cesarean Delivery - A Randomized Study.Ogunkua, O.T., et al. (2022). American Journal of Obstetrics & Gynecology.  [Record in progress]

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia.Peffault de Latour, R., et al. (2022). The New England Journal of Medicine.

Iron chelation therapy in patients with low- to intermediate-risk myelodysplastic syndrome: A systematic review and meta-analysis.Yang, S., et al. (2021). British Journal of Haematology. [Record in progress]

26 February 2022 (Saturday) - Oncologist Update

The Oncologist” newsletter is now being created by the nice people at Oxford Academic. Whilst it is good that this resource is available free to anyone who wants it, much of it goes over my head. You can see what I mean by clicking here