2 February 2026 (Monday) - Learning Monday

 


It’s not Immune thrombocytopenia. The platelet count is too high and the patient would have had bruising and other symptoms which would have come to light before any surgery.
It’s not Wiskott-Aldrich syndrome as that has small platelets.
It’s not DIC as the clotting isn’t outside the normal range.
 
Large and pale platelets – grey platelet syndrome…

29 January 2026 (Thursday) - IBMS Newsletter

The IBMS sent their newsletter today. You can see it by clicking here. In the past I’ve been less than complimentary about it… and I am again today. Again there’s absolutely nothing of interest to me in it. And I’ll make the observation that back in the day (before the Internet) people only joined the IBMS because their magazine was *the* place where jobs in this line of work were advertised.

There’s only one job advert in this month’s newsletter (I counted)…

28 January 2026 (Wednesday) - Levetiracetam


 I saw an interesting case today. Clearly an iron-deficiency anaemia. They are quite common. But this one was in someone who was on Levetiracetam. It’s an anticonvulsant which whilst supposedly not causing iron deficiency, it is recommended that people on that medication should take iron supplements.

I’ve updated my atlas to include this case, and here’s some expert opinion on the matter

27 January 2026 (Tuesday) - BTLP-TACT Exercise

Time for another BTLP-TACT exercise. I was presented with two cases:
 
77343 – a ninety-eight year-old chap with sickle cell disease needing two units of blood
He grouped as B Rh(D) Positive with a negative antibody screen
I selected two units of O Rh(D) Positive HbS negative blood
 
61659 – a twenty-eight year-old woman with ITP needing group and save
She grouped as O Rh(D) Positive with a negative antibody screen.
 
I got the green light.

26 January 2026 (Monday) - Transfusion Evidence Alert Update

The nice people at the Transfusion Evidence Alert sent their update today. Again there was talk of frozen platelets. It would seem they aren’t as good as fresh ones, but fresh ones are only good for five days; frozen ones keep for two years…

ARTICLE OF THE MONTH

TOP ARTICLES

Engasertib versus placebo for bleeding in hereditary hemorrhagic telangiectasia.
Al-Samkari, H., et al. (2025). The New England Journal of Medicine.

Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birthweight infants.
Andersen, C., et al. (2025). The Cochrane Database of Systematic Reviews.

Red cell physiologic stress results in lower quality transfusions: a randomized trial in adults with sickle cell disease.
Karafin, M.S., et al. (2025). Blood Red Cells Iron.

Safety and pharmacodynamics of the ferroportin inhibitor vamifeport in patients with non-transfusion-dependent β-thalassemia: results from a randomized phase 2a study.
Kattamis, A., et al. (2025). Orphanet Journal of Rare Diseases.

The efficacy and safety of thrombopoietin receptor agonists in solid tumors with chemotherapy-induced thrombocytopenia: a systematic review and network meta-analysis of randomized controlled trials.
Lai, Y., et al. (2025). Frontiers in Pharmacology.

Effect of multidisciplinary team-based refined nursing on outcomes in elderly patients with liver cirrhosis and upper gastrointestinal bleeding.
Li, S., et al. (2025). Journal of Visualized Experiments: JoVE.

A standard blood bank donation improves cardiometabolic health of donors: a double-blind randomised controlled trial.
Mora-Gonzalez, D., et al. (2025). British Journal of Haematology. [Record in progress].

Risk assessment tools for predicting transfusion in surgery: a systematic review and meta-analysis.
Seyahian, A., et al. (2025). Health Technology Assessment. [Record in progress].

Liberal versus restrictive red blood cell transfusion thresholds in acute acquired brain injury: a systematic review and meta-analysis.
Sud, S., et al. (2025). BMJ Open.

23 January 2026 (Friday) - UKAS Update

The nice people at the UK Accreditation Service sent their update today. You can read it by clicking here. I read it because making sure that I operate within the scope of their rules is a major part of what I do every day.
But…
This update covered the accreditation of bodies involved with event management, railway supply chains, water management and announced the launch of an accreditation for A.I. management systems…
I try not to be a cynical old reactionary. I realise that what I do needs some sort of oversight. But how can any supervisory body with such a wide-ranging remit do much more than check the paperwork that the bosses fill in?