8 May 2026 (Friday) - BTLP-TACT Exercise

It can be no surprise to anyone that I’ve had yet another email from the nice people at BTLP-TACT whinging that I’m not doing enough exercises. So here we go again…
 
I was presented with two cases:
 

93449 – a sixty-nine year-old chap with sickle cell disease needing two units of blood

He grouped as O Rh(D) Positive with a negative antibody screen.

I selected two units of O Rh(D) Positive.

62030 – a sixty-eight year-old chap needing group and save for a fem-pop bypass.

He grouped as A Rh(D) Positive also with a negative antibody screen.

 
I got it right… I must admit I was amazed. The connection to the server dropped out several times…

7 May 2026 (Thursday) - Horiba Update

The nice people at Horiba sent their update today. I’ll say one thing for their update – its format seems to change from month to month.
This month featured Sezary syndrome, G6PD, and a quiz which was MAHA.
This is the sort of thing I want for CPD…

5 May 2026 (Tuesday) - Fritsma Factor Newsletter


And with my poor brain already overloaded so the Fritsma Factor Newsletter arrived in my in-box.

5 May 2026 (Tuesday) - Transfusion Evidence Library Update

The nice people at the Transfusion Evidence Library sent their update today. As always it boggled my poor brain. It was a lot to take in…

ARTICLE OF THE MONTH

Prehospital whole blood in traumatic hemorrhage - a randomized controlled trial.
Smith, J.E., et al. (2026). The New England Journal of Medicine. [Record in progress].
PICO SUMMARY

TOP ARTICLES

Romiplostim versus placebo for chemotherapy-induced thrombocytopenia.
Al-Samkari, H., et al. (2026). The New England Journal of Medicine.

Impact of feeding strategies during red blood cell transfusion on cerebral and splanchnic oxygenation in preterm infants: randomized pilot study.
Aslan Tuncay, S., et al. (2026). Journal of Neonatal-Perinatal Medicine. [Record in progress].

Erythropoiesis-stimulating agents to reduce heart failure hospitalization: a systematic review and meta-analysis.
Bunting, K.V., et al. (2026). European Journal of Heart Failure.

Substantial international variation in the cost of blood group and save and crossmatch: a systematic review.
Fabiano, G., et al. (2026). British Journal of Haematology.

Statistically significant results favored in abstracts of platelet rich plasma treatment of knee osteoarthritis: a systematic review and spin analysis.
Fullano, G.D., et al. (2026). Arthroscopy.

Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis.
Kimber, C., et al. (2026). BMC Neurology.

Blood donation practices and behavioral intentions: a scoping review using the theory of planned behavior.
Lakew, G., et al. (2026). PLoS One.

Prophylactic haemostatic treatment to control iatrogenic bleeding during endobronchial biopsy (PROTECT study): a multicentre, randomised, single-blind, placebo-controlled study.
Li, B., et al. (2026). Chest. [Record in progress].

Artificial intelligence implementation in transfusion medicine: addressing the challenges of clinical adoption.
Maynard, S., et al. (2026). Transfusion Medicine Reviews.

Albumin replacement therapy in septic shock: a randomized clinical trial.
Sakr, Y., et al. (2026). JAMA Network Open.

3 May 2026 (Sunday) - Babeosis

I’ve (so far) never seen a case of babeosis, but it can only be a matter of time.
Apparently severe cases are treated with exchange transfusions
Forewarned is forearmed

 

3 May 2026 (Sunday) - Slide Saturday Challenge

Flame cells… I don’t think I’ve ever actually seen them in real life


2 May 2026 (Saturday) - Unexpected Thrombocytosis

I was sitting in the garden enjoying the Bank Holiday sunshine when my phone beeped. A colleague wanted my opinion on a blood film…
A sample taken in the community had been somehow left in the sunshine, the red cells had cooked and broken up, and the analyser had counted the fragments as platelets.