28 April 2017 (Friday) - Immunology Day

I received the latest immunology newsletter from the nice people at Wiley today:

News | IgE articles | Virtual Issues & Special Issues | Journals | Latest Books

News

The British Society for Immunology is delighted to announce Leonie Taams as the new Editor-in-Chief of Clinical & Experimental Immunology. Leonie is Professor of Immune Regulation and Inflammation at King’s College London, and takes over from Mark Peakman. Mark oversaw a period of growth in his two terms as EiC and the BSI would like to express their gratitude to him for his outstanding contribution to the journal.   Immunity, Inflammation and Disease is delighted to announce that is it now indexed in MEDLINE®. MEDLINE® is the National Library of Medicine® (NLM®) journal citation database. Started in the 1960s, it now provides more than 23 million references to biomedical and life sciences journal articles back to 1946. Submit your paper to Immunity, Inflammation and Disease   Back to Top ▲

IgE articles – all free to read

Chlorhexidine allergy in four specialist allergy centres in the United Kingdom, 2009–13: clinical features and diagnostic tests Low immunoglobulin E flags two distinct types of immune dysregulation     Specialized proresolving mediators (SPMs) inhibit human B-cell IgE production Bortezomib treatment diminishes hazelnut-induced intestinal anaphylaxis in mice Somatic mosaicism in B cells of a patient with autosomal dominant hyper IgE syndrome     Effect of anti-IgE in occupational asthma caused by exposure to low molecular weight agents IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment     The role of dietary interventions in the prevention of IgE-mediated food allergy in children Non-IgE-mediated gastrointestinal food allergies in children     IgE mediated sensitisation to aeroallergens in an asthmatic cohort: relationship with inflammatory phenotypes and disease severity     Eosinophilic esophagitis: unclear roles of IgE and eosinophils     Elevated total serum immunoglobulin E (>1000 IU/mL): implications?     Immunoglobulin A: magic bullet or Trojan horse?     Back to Top ▲

Virtual Issues & Special Issues

Explore the latest Virtual Issues from Clinical & Experimental Immunology and Immunology - all articles free to read.   Immunosenescence in health and disease   Drivers and Regulators of adaptive immunity – new concepts   New free-to-read Zika Special Issue from American Journal of Reproductive Immunology Parasite Immunology Special Issue on MicroRNAs in Host-parasite Interactions Brand new free-to-read APMIS Special Issue on Biofilm Infections Back to Top ▲

Journals

Watch the latest Immunological Reviews video with Barton F. Haynes discussing Antibodies and Immunity to HIV-1, giving an overview of topics discussed in Volume 275.     Basophil activation test: Implementation and standardization between systems and between instruments     Sequential epitopes of Dermatophagoides farinae allergens identified using peptide microarray‐based immunoassay     Increasing time interval and decreasing allergen dose interval improves ex vivo desensitization of human blood basophils     Interactions of nanomaterials with the immune system     Anti‐inflammatory effects of the petasin phyto drug Ze339 are mediated by inhibition of the STAT pathway     Effects of Hovenia dulcis Thunb. extract and methyl vanillate on atopic dermatitis-like skin lesions and TNF-α/IFN-γ-induced chemokines production in HaCaT cells     Changes in biomarkers during a six-month oral immunotherapy intervention for cow's milk allergy     Basophil CD63 expression in chronic spontaneous urticaria: correlation with allergic sensitization, serum autoreactivity and basophil reactivity     Efficacy and safety of LAS41008 (dimethyl fumarate) in adults with moderate-to-severe chronic plaque psoriasis: a randomized, double-blind, Fumaderm®- and placebo-controlled trial (BRIDGE)     Host- and pathogen-derived adjuvant coatings on protein nanoparticle vaccines     Glycosylation of monoclonal antibody products: Current status and future prospects     A rapid differential display analysis of nasal swab fingerprints to distinguish allergic from non-allergic rhinitis subjects by mesoporous silica particles and MALDI-TOF mass spectrometry     Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants     The sensitization pattern differs according to rhinitis and asthma multimorbidity in adults: the EGEA study The clinical and immunological effects of Pru p 3 sublingual immunotherapy on peach and peanut allergy in patients with systemic reactions Back to Top ▲

Latest Books

Mount Sinai Expert Guides: Allergy and Clinical Immunology Edited by Hugh A. Sampson     Roitt's Essential Immunology, 13th Edition by Peter J. Delves, Seamus J. Martin, Dennis R. Burton & Ivan M. Roitt

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27 April 2017 (Thursday) - The Oncologist

I've signed up to "The Oncologist" - a free e-newsletter. One arrived today:

The BALLET Study: Italian Cohort Subset Analysis

Daniele Generali et al.

 

The BALLET study was a European open‐label, multicenter, expanded access study designed to allow treatment with everolimus plus exemestane in postmenopausal women with hormone receptor‐positive metastatic breast cancer progressed following prior endocrine therapy. This article evaluates whether previous chemotherapy in the metastatic setting affects the safety profile of the combination regimen of everolimus and exemestane was conducted on the Italian subset.

 

In the News   Experimental Drug Could Lead to Potent Combination in Breast and Other Cancers   Why Latest Work from Top UK Cancer Researchers Could Hold Potential for Future ‘Game-Changing’ Treatments for Rare Bile Duct Cancer, Cholangiocarcinoma   Targeting Cancer Spread: Keeping Breast Tumours Under LOX and Key

CME Activities   Management of Cancer in the Older Age Person: An Approach to Complex Medical Decisions     Multidisciplinary Management of Breast Cancer During Pregnancy ADVERTISEMENT

Genomics of a Mitochondria-Rich Tumor   From the most recent Chabner Colloquium and STO Annual Meeting Raj Gopal, MD, PhD, Massachusetts General Hospital, Harvard Medical School discussed how researchers focused on simultaneous analysis of both mitochondrial DNA (mtDNA) and nuclear DNA (nuDNA) for somatic events that may contribute to oncocytic cellular change to learn more about the role of mitochondrial metabolism in tumors. Watch Now >

26 April 2017 (Wednesday) - A.S.H.

Why has it taken me so long to discover the American Society of Hematology’s website?

I’ve signed up – they say there are free weekly newsletters. Something for nothing is always good…

25 April 2017 (Tuesday) - Transfusion News email

My inbox has been busy today...

Prophylactic Platelet Transfusions are Not Superior to Supportive Care for Dengue Patients with Thrombocytopenia

April 12, 2017
According to the World Health Organization, the incidence of dengue has increased 30-fold in the past 50 years, and over half of the world’s population is at risk of infection. Acute infection with dengue virus typically causes flu-like symptoms, but can also be associated with severe bleeding and thrombocytopenia. In order to determine if prophylactic [Read More]

Current Evidence Suggests that Non-invasive Procedures are Best to Treat Fetal and Neonatal Alloimmune Thrombocytopenia

April 5, 2017
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) occurs when maternal alloantibodies develop against fetal platelet antigens. FNAIT may cause severe bleeding in the fetus, including intracranial hemorrhage and long-term disabilities, especially in subsequent pregnancies. Treatments for FNAIT include fetal blood sampling with intrauterine platelet transfusions, or maternal IV immunoglobulin transfusions with or without steroids. In order [Read More]

Transfusion News is brought to you by Bio-Rad. Read about Bio-Rad’s IH-Gel Cards here:

A Pioneer in Gel Technology Bio-Rad’s IH-Gel Cards allow easy results interpretation, both manually and by automated means. Simple, flexible with maximum productivity. With Bio-Rad, you get more gel card configurations, the right gel card configurations, and eliminate unnecessary testing. [Read More]

25 April 2017 (Tuesday) - Post-Transplant Lympoproliferative Disorder

The Lablogatory people emailed me with a case study today:

“A 7 year old male with a history of restrictive cardiomyopathy status-post orthotopic heart transplant in June, 2010 that was on maintenance doses of tacrolimus and mycophenolate mofetil presented to his primary pediatrician left neck swelling. Starting in January 2017, the patient began with neck pain and swelling in….”

You can read the full article here

A rather interesting post-transplant lympoproliferative disorder…. Wish I could find more case studies like this  

25 April 2017 (Tuesday) - World Immunisation Week

I got an email this morning:

Wiley supports the World Health Organization's World Immunization Week, April 24-30 by showcasing the latest research on vaccines. Follow this initiative through social media. Read and share the research with your colleagues. All articles are free until May 30^th.

Can infant vaccination prevent pneumococcal meningitis outbreaks in sub-Saharan Africa? Tropical Medicine & International Health

Household experience and costs of seeking measles vaccination in rural Guinea-Bissau Tropical Medicine & International Health

Seroepidemiology: an underused tool for designing and monitoring vaccination programmes in low- and middle-income countries Tropical Medicine & International Health

Effectiveness of the South African expanded program of immunization against hepatitis B in children infected with human immunodeficiency virus-1 living in a resource-limited setting of Kwazulu-Natal Journal of Medical Virology

British HIV Association Guidelines on the Use of Vaccines in HIV-Positive Adults 2015 HIV Medicine

Workshop report: Immunoassay standardisation for “universal” influenza vaccines Influenza and Other Respiratory Viruses

Estimating vaccine effectiveness in preventing laboratory-confirmed influenza in outpatient settings in South Africa, 2015 Influenza and Other Respiratory Viruses

Prevention strategies for blood-borne viruses—in the Era of vaccines, direct acting antivirals and antiretroviral therapy Reviews in Medical Virology

Aging of the immune system: Focus on inflammation and vaccination European Journal of Immunology

A dual purpose universal influenza vaccine candidate confers protective immunity against anthrax Immunology