20 July 2026 (Monday) - Transfusion Evidence Library Update

Tranexamic acid again !!

The article about alloimmunization in sickle cell patients was interesting. In the study a third of them had formed antibodies. Clearly people on long-term transfusions should have blood matched as closely as possible…

I’m reminded of a thread I saw on one of the work-related Facebook pages which was talking about artificial oxygen carriers. If ever there was a cohort of patients that could use them…

ARTICLE OF THE MONTH

Hospital policy of tranexamic acid to reduce transfusion in major noncardiac surgery. Houston, B.L., et al. (2026). The New England Journal of Medicine.
PICO SUMMARY

 

 

TOP ARTICLES

Global prevalence of alloimmunization in adults with sickle cell disease receiving red blood cell transfusions: a systematic review and meta-analysis.
Alsalman, M., et al. (2026). Journal of Clinical Medicine.

Effect of continuous non-invasive hemoglobin monitoring on blood transfusion and mortality in hip surgeries: a randomized controlled study.
Dinçer Yeşilnacar, M.E., et al. (2026). Journal of Clinical Practice and Research.

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors.
Geneen, L.J., et al. (2026). The Cochrane Database of Systematic Reviews.

Clinical trial: predicting response to iron therapy in patients with active inflammatory bowel disease using hepcidin and functional iron indices: a multicentre randomised trial.
Koppelman, L.J.M., et al. (2026). Alimentary Pharmacology & Therapeutics.

Clinical efficacy of different blood purification modes on severe acute pancreatitis: a systematic review and network meta-analysis.
Li, P., et al. (2026). Frontiers in Medicine.

Effect of tranexamic acid for acute spontaneous intracerebral haemorrhage: a systematic review and individual patient data meta-analysis.
Menon, C.S., et al. (2026). Journal of Neurology, Neurosurgery, and Psychiatry. [Record in progress].

Artificial Intelligence-based predictive models for adverse blood donor reactions: a systematic review of immediate and delayed events and clinical data approaches.
ShojaeiBaghini, M., et al. (2026). BMC Medical Informatics and Decision Making. [Record in progress].

The effect of active warming and conventional body temperature management on perioperative blood loss and coagulation function in patients undergoing scoliosis correction: a multicenter randomized controlled trial.
Yan, W., et al. (2026). European Spine Journal. [Record in progress].