15 April 2025 (Tuesday) - Transfusion Evidence Library Update

The nice people at the Transfusion Evidence Library sent their update today. Quite a bit to take in, but it pays to pay attention. I’m not quite sure how to word it… either best practice is modified by experience, or fashions change.
Back in the day whole blood transfusion was a thing. Then it became frowned upon. Now it is back in vogue.

ARTICLE OF THE MONTH

Safety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 study.
Kuter, D.J., et al. (2025). Blood. [Record in progress].
PICO SUMMARY

 

 

TOP ARTICLES

The effect of delayed cord clamping on early cardiac and cerebral hemodynamics, mortality, and severe intraventricular hemorrhage in preterm infants < 32 weeks: a systematic review and meta-analysis of clinical trials.
Aljohani, E., and Goyal, M. (2025). European Journal of Pediatrics.

A cost-effective measure to prevent hemorrhage in ultrasound-guided percutaneous liver biopsy.
Cai, Q., and Wu, X. (2025). BMC Gastroenterology.

Multicentre randomised controlled trial of a self-assembling haemostatic gel to prevent delayed bleeding following endoscopic mucosal resection (PURPLE Trial).
Drews, J., et al. (2025). Gut. [Record in progress].

Plasma exchange therapy for the post COVID-19 condition: a phase II, double-blind, placebo-controlled, randomized trial.
España-Cueto, S., et al. (2025). Nature Communications.

Facilitators of and barriers to blood donation among voluntary non-remunerated blood donors in sub-Saharan Africa: a scoping review.
Gondwe, A., et al. (2025). Vox Sanguinis. [Record in progress].

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19: an international, randomised, open-label trial.
Hoffmann, S., et al. (2025). EBioMedicine.

Effect of fresh whole blood donation on human performance in United States Special Forces.
Houser, A.P., et al. (2025). Journal of Special Operations Medicine.

Implementation strategies for WHO guidelines to prevent, detect, and treat postpartum hemorrhage.
Semrau, K., et al. (2025). The Cochrane Database of Systematic Reviews.

Red blood cell transfusion management for people undergoing cardiac surgery for congenital heart disease.
Wilkinson, K.L., et al. (2025). The Cochrane Database of Systematic Reviews.