17 October 2024 (Thursday) - Transfusion Evidence Library Update

The nice people at the Transfusion Evidence Library sent their update with World Trauma Day 2024 in mind. If one thing has changed over the last forty years it is how little blood is used in trauma cases these days compared to the bad old days.

Is that because of tranexamic acid?

Top article

Pelvic packing or endovascular interventions: Which should be given priority in managing hemodynamically unstable pelvic fractures? A systematic review and a meta-analysis. Zhang, D., et al. (2024). Surgery Open Science.
PICO SUMMARY

 

Selected articles

The efficacy and safety of pre-hospital plasma in patients at risk for hemorrhagic shock: an updated systematic review and meta-analysis of randomized controlled trials. Abuelazm, M., et al. (2024).  European Journal of Trauma and Emergency Surgery. [Record in progress].

Prehospital tranexamic acid in trauma patients: a systematic review and meta-analysis of randomized controlled trials. 
Acharya, P., et al. (2023). Frontiers in Medicine.

Management of non-compressible torso hemorrhage of the abdomen in civilian and military austere environments: a scoping review.
Adams, D., et al. (2024). Trauma Surgery & Acute Care Open.

Efficacy and safety of early administration of 4-factor prothrombin complex concentrate in patients with trauma at risk of massive transfusion: the PROCOAG randomized clinical trial.
Bouzat, P., et al. (2023). JAMA.

Prothrombin complex concentrate (PCC) for treatment of trauma-induced coagulopathy: systematic review and meta-analyses.
Hannadjas I., et al. (2023). Critical Care.

Emergency department resuscitative endovascular balloon occlusion of the aorta in trauma patients with exsanguinating hemorrhage: the UK-REBOA randomized clinical trial.
Jansen J.O., et al. (2023). JAMA.

Predicting blood transfusion following traumatic injury using machine learning models: a systematic review and narrative synthesis.
Oakley W., et al. (2024). The Journal of Trauma and Acute Care Surgery.

Early cold stored platelet transfusion following severe injury: a randomized clinical trial.
Sperry, J.L., et al. (2024). Annals of Surgery.

Efficacy and safety of tranexamic acid in acute traumatic brain injury: a meta-analysis of randomized controlled trials.
Zhang, M., and Liu, T., (2024). The American Journal of Emergency Medicine.