19 March 2019 (Monday) - Transfusion Evidence Alert

The nice people at the Transfusion Evidence Alert sent their update today. Quite a few useful snippets:

TOP ARTICLES

Efficacy and safety of prothrombin complex concentrate for vitamin K antagonist-associated intracranial hemorrhage: a systematic review and meta-analysis
Pan, R., Cheng, J., et al., Neurological sciences 2019

Desmopressin acetate (DDAVP) for preventing and treating acute bleeds during pregnancy in women with congenital bleeding disorders
Karanth, L., Barua, A., et al. The Cochrane database of systematic reviews 2019
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Comparison of intravenous, topical or combined routes of tranexamic acid administration in patients undergoing total knee and hip arthroplasty: a meta-analysis of randomised controlled trials
Sun, Q., Li, J., et al. BMJ Open 2019.
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Tranexamic Acid in Cerebral Hemorrhage: A Meta-Analysis and Systematic Review
Hu, W., Xin, Y., et al. CNS Drugs 2019.

Well-being and return rate of first-time whole blood donors
Jansen, P., Sumnig, A., et al. Vox Sanguinis 2019

Why does a point of care guided transfusion algorithm not improve blood loss and transfusion practice in patients undergoing high-risk cardiac surgery? A prospective randomized controlled pilot study
Lehmann, F., Rau, J., et all. BMC Anesthesiology 2019.
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Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial
Hernandez, G., Ospina-Tascon, G. A., et al. JAMA 2019.

Eltrombopag treatment during induction chemotherapy for acute myeloid leukaemia: a randomised, double-blind, phase 2 study
Frey, N., Jang, J. H, et al. The Lancet. Haematology 2019.

A phase III study comparing secondary long-term prophylaxis versus on-demand treatment with vWF/FVIII concentrates in severe inherited von Willebrand disease
Peyvandi, F., Castaman, G., et al. Blood transfusion 2019
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Intravenous compared with oral iron for the treatment of iron-deficiency anemia in pregnancy: a systematic review and meta-analysis Lewkowitz, A. K., Gupta, A., Journal of perinatology 2019.