21 December 2018 (Friday) - Transfusion Evidence Alert

Today I received the “Transfusion Evidence Alert” email. This one is generally far more relevant to my day-to-day practice than any of the other “Evidence Alerts”…

Randomized Trial of Platelet-Transfusion Thresholds in Neonates Curley A, Stanworth SJ. The New England Journal of Medicine 2018.  Free Full Text (after registration)

Optimal use of tranexamic acid for total hip arthroplasty: A network meta-analysis Yoon BH, Kim TY, et al., PLOS One 2018 Free Full Text Massive Transfusion Protocols in Non-Trauma Patients: A Systematic Review and Meta-Analysis Sommer N, Schnuriger B, et al. The Journal of Trauma and Acute Care Surgery 2018 Systematic review and meta-analysis of the effect of iron chelation therapy on overall survival and disease progression in patients with lower-risk myelodysplastic syndromes Zeidan AM, Giri S et al. Annals of Hematology 2018. Effects of anemia and blood transfusion on clot formation and platelet function in patients with septic shock: a substudy of the randomized TRISS trial Russell L, Holst LB, et al. Transfusion 2018 The impact of hypothermia on outcomes in massively transfused patients Lester ELW, Fox EE, et al. The New England Journal of Medicine 2018 Multimodal Patient Blood Management Program Based on a Three-pillar Strategy: A Systematic Review and Meta-analysis Althoff FC, Neb H, et all. Annals of Surgery 2018.  Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial Myles PS, Smith JA, et al. The Journal of Thoracic and Cardiovascular Surgery 2018 Safety and efficacy of iron therapy on reducing red blood cell transfusion requirements and treating anaemia in critically ill adults: A systematic review with meta-analysis and trial sequential analysis Shah A, Fisher SA, et al. Journal of Critical Care 2018 Older Blood Is Associated With Increased Mortality and Adverse Events in Massively Transfused Trauma Patients: Secondary Analysis of the PROPPR Trial Jones AR, Patel RP, et al. Annals of Emergency Medicine 2018