13 March 2024 (Wednesday) - Hyperthyroidism

We had a patient today with a mild neutropenia. The patient’s diagnosis was hyperthyroidism.

It transpires that treatment of hyperthyroidism often causes a neutropenia which resolves on cessation of treatment.

Something to bear in mind.


12 March 2024 (Tuesday) - IBMS Newsletter

The IBMS Newsletter appeared in my in-box this morning. You can read it by clicking here.
It is widely said that in this life things go full-circle. I suspect that in thirty years’ time a future issue of the IBMS gazette will feature articles on the latest advances on blood testing analysers and reagent kits, and tutorials on cell morphology and interpretations of haemoglobinopathy traces. And the olduns of that era (today’s trainees) will hark back to the halcyon days of 2024 when the IBMS focused on what mattered to them; committees and awards and strange catchphrases.

12 March 2024 (Tuesday) - Oncology Central

The nice people at Oncology Central sent their update today. Much (most) of it went over my head, but one or two things stuck

 

10 March 2024 (Sunday) - BTLP-TACT Exercise

Time for another BTLP-TACT exercise. I had one case – a thirty-four year-old woman in the out patients department needing group & save for “maternal alloantibody”.
 
She grouped as O Rh(D) Negative with a negative antibody screen.
 
“maternal alloantibody” negative (!)
I got the green light

8 MArch 2024 (Friday) - NEQAS 2401 DM


This image is taken from a blood film of a man aged 61 years. A blood count sent by the GP showed that the white cell count was 40 x 10^9/L, Hb of 79 g/L and platelets of 118 x 10^9/L. What are your findings?” 
 
 

 Rbc 

 

Anisopoikilocytosis 

Nucleated red cells 

Polychromasia 

Spherocytes 

Tear drop cells 

 

Wbc 

 

Auer rods 

Blast cells 

Dohle bodies 

Dysplastic neutrophils 

Hypersegmented neutrophils 

Left shifted neutrophils 

Myelocytes 

Plts 

 

Grian plts 

Grey plts 

Megakaryocyte fragments 

 

 
In the absence of any useful clinical information I felt this was a case of primary myelofibrosis transforming into something nasty.
It was.
However I feel I must ask myself what I meant by “Grian plts” Bearing in mind nearly two months passed between my looking at the film and getting the results I have no recollection.

8 March 2024 (Friday) - NEQAS Parasitology

2401 PA1
 
In my notes I actually wrote “odd things… probably parasites”. They were parasites of P malariae.
 
But this was a thick film… I saw what could have been parasites, but I don’t pretend to be an expert at thick films.
In reality I would have asked for a second opinion. It wouldn’t have been missed, and that is the main thing.
 
 
2401 PA2
 
I saw parasites of P. falciparum with a parasitaemia of 4%. The consensus opinion was that the parasitemia was 1.5%. I’m over-estimating, but better over than under.
 
I’ll claim that as a success.

7 March 2024 (Thursday) - BTLP-TACT Exercise

Time for another BTLP-TACT exercise. I must admit I approached this with a sense of “how will I fail this time?
I had one case – a forty-four yar-old woman in the out-patients department needing group and save. She grouped as O Rh(D) Positive with a negative antibody screen.
 
I got the green light.