15 June 2023 (Thursday) - Oncology Central Update

The editor of Oncology Central claims that a lower body weight and being physically active could reduce risk of cancer. It probably could. If there is something which *really* annoys me is thin people making these statements. I’ve fought a fifty-year battle against being overweight, have tried every diet there is…

Editor's pick

Lower body weight and being physically active could reduce risk of dying from breast cancer What links are there between body weight, physical activity, diet and the risk of death after a breast cancer diagnosis? Find out in our latest editorial article.

Latest news

AI-designed drug, ISM3091, granted US FDA IND approval Read about the US FDA initial investigational new drug (IND) approval of ISM3091 for the treatment of solid tumors. The drug was designed using a machine learning platform.

ASCO23: trastuzumab deruxtecan proves to be effective on multiple HER-2 expressing tumors The Phase II DESTINY-PanTumor02 study has demonstrated the effectiveness of Enhertu® (trastuzumab deruxtecan) at treating HER2-expressing solid tumors, including bladder, cervical and pancreatic cancer.

ASCO23: adjuvant ribociclib yields promising results for early-stage breast cancer A Phase III clinical trial has demonstrated promising results for the use of Kisqali® (ribociclib) with endocrine therapy for people with Stage IIA, IIB, or III HR-positive, HER2-negative breast cancer who are at risk for recurrence.

Journal article of the week

Exosome-derived miRNAs regulate macrophage-colorectal cancer cell cross-talk during aggressive tumor development

This review discusses exosomal miRNAs derived both from colorectal cancer cells and macrophages that promote or inhibit cancer aggression. Various miRNA-based therapeutic approaches are also explored.