79396 – A thirty-eight year-old chap in the haematology clinic requiring eight units of blood for an exchange transfusion (do they still happen?) for sickle cell diseaseHe grouped as A Rh(D) Positive with a weak D. With absolutely no idea what the “less than perfect(!)” software was expecting I called it indeterminate. But this is crap isn’t it (to be blunt). Given a patient in the haematology clinic known to have sickle cell disease requiring exchange transfusion, how likely is it that this dubious D group wouldn’t have been encountered and investigated years ago?The antibody screen was negative, for which I was grateful.I selected eight units of A Rh(D) Negative blood knowing full well the software wouldn’t be happy.16094 – A thirty-three year-old woman needing four units of blood for surgery.She too was a pain in the glass (as my grandson would say). An indeterminate ABO group but was Rh (D) Negative, and a positive antibody screen (in cells 1 & 2). I selected panels…The IAT and enzyme panels were positive in cells 1, 2. 3. and 5 corresponding with anti-D and anti-E but not excluding anti-CwI selected four units of O Rh(D) Negative which were also E and Cw negative
21 December 2023 (Thursday) - Swearing at the BTLP-TACT
19 December 2023 (Tuesday) - Transfusion Evidence Alert Update
ARTICLE OF THE MONTH Restrictive or liberal transfusion strategy in myocardial infarction and anemia. +++++ |
13 December 2023 (Thursday) - HCPC Update
12 December 2023 (Tuesday) - BTLP-TACT Exercise
12 December 2023 (Tuesday) - Westgard QC Update
11 December 2023 (Monday) - ESR
10 December 2023 (Sunday) - BTLP-TACT
13485 – a ninety-two year-old chap in out patients requiring two units of blood within the hourHe grouped as A Rh(D) Positive with ntibody screen positive in cell 2.I performed panels.The enzyme and IAT panels were positive in cells 2 and 6 which was consistent with anti-KI selected two units of A Rh(D) Positive which were K Negative99315 – a fifty-eight year-old woman in A&E requiring group and save.She grouped as A Rh(D) Negative with antibody screen positive in cell 3.I performed panels.The enzyme and IAT panels were positive in cell 8 which was consistent with anti-Kp(a)
7 December 2023 (Thursday) - Medical Laboratory Observer
6 December 2023 (Wednesday) - NEQAS 2304 PA
6 December 2023 (Wednesday) - NEQAS 2307 BF
2307 BF1Hypochromic (consensus 8th)Lymphocytosis (some spiky?) (consensus 1st)smear cells (consensus 7th)low plts (consensus 2nd)? CLL (it was)2307 BF2burr cells (consensus 6th)nrbc (consensus 1st)lymphocytosis / blasts (consensus 2nd)smear cells (consensus 4th)low plts (consensus 3rd)? lymphoma (it was)
I got that right
5 December 2023 (Tuesday) - Fritsma Factor Newsletter
The Fritsma
Factor newsletter arrived in my in-box today… Perhaps I’m being unfair to
compare it tl last week’s update from Stago, but this one wasn’t one of the
better ones.
That’s rather ungrateful of me, isn’t it?
4 December 2023 (Monday) - Transfusion Evidence Alert Update
The nice people at the Transfusion Evidence
Library sent quite a few articles today. The COVID plasma debate rages on – is it
any good or not? And one unit transfusions are supposedly as good as two units…
Top Article
Selected Articles
Effect of donor sex on recipient mortality in transfusion.
Chasse, M., et al. (2023). The New England Journal of Medicine.
Effect of single-unit transfusion in patients treated for haematological disease including acute leukemia: a multicenter randomized controlled clinical trial.
Chantepie, S.P., et al. (2023). Leukemia Research.
Pathogen inactivation methods to prevent transfusion-transmissible arboviruses.
Giménez-Richarte, Á., et al. (2023). Tropical Medicine & International Health
Prehospital tranexamic acid for severe trauma.
Gruen, R. L., et al. (2023). The New England Journal of Medicine.
Convalescent plasma for people with COVID-19: a living systematic review.
Iannizzi, C., et al. (2023). The Cochrane Database of Systematic Reviews.
Comparison of quantitative and calculated postpartum blood loss after vaginal delivery.
Madar, H., et al. (2023). American Journal of Obstetrics & Gynecology.
Two-year outcomes following a randomised platelet transfusion trial in preterm infants.
Moore C.M., et al. (2023). Archives of Disease in Childhood. Fetal and Neonatal Edition.
Men who have sex with men and risk for transfusion-transmissible infections in blood donors in Western countries: a systematic review update.
Schroyens, N., et al. (2023). Vox Sanguinis.
Platelet transfusion before CVC placement in patients with thrombocytopenia.
Van Baarle, F.L.F., et al. (2023). The New England Journal of Medicine.
30 November 2023 (Thursday) - Stago Newsletter
27 November 2023 (Monday) - Transfusion Evidence Library Update
TOP ARTICLES
Effect of Benson's relaxation technique versus music intervention on physiological parameters and stress of children with thalassemia during blood transfusions: A randomized controlled trial.
Badr, E. A., et al. (2023). Journal of Pediatric Nursing. [Record in progress].
Cerebral and intestinal oxygen saturation of different volumes of red blood cell transfusion in preterm infants.
Chen, R., et al. (2023). Transfusion and Apheresis Science. [Record in progress].
Tranexamic acid for percutaneous nephrolithotomy.
Cleveland, B., et al. (2023). The Cochrane Database of Systematic Reviews.
Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage.
Eilertsen, H., et al. (2023). The Cochrane Database of Systematic Reviews.
Intravenous iron administration before cardiac surgery reduces red blood cell transfusion in patients without anaemia.
Friedman, T., et al. (2023). British Journal of Anaesthesia.
Effect of red blood cell storage time in pediatric cardiac surgery patients: a subgroup analysis of a randomized controlled trial.
Martin, S. M., et al. (2023). JTCVS Open.
Convalescent plasma for Covid-19-Induced ARDS in mechanically ventilated patients.
Misset, B., et al. (2023). The New England Journal of Medicine.
Small-volume blood collection tubes to reduce transfusions in intensive care: the STRATUS randomized clinical trial.
Siegal, D. M., et al. (2023). JAMA.
Allogeneic serum eye drops: a randomized clinical trial to evaluate the clinical effectiveness of two drop sizes.
Vermeulen, C., et al. (2023). Ophthalmology and Therapy.