31 May 2021 (Monday) - Stem Cell Evidence Alert

A couple of days ago I said “I do like the “Transfusion News” updates. They don’t swamp me with information, and they are regular. Little and often – as CPD should be…
Today I got the Stem Cell Evidence Alert… I don’t get them very often, and when I do my poor brain overloads…

 

ARTICLE OF THE MONTH

HLA Haploidentical versus Matched Unrelated Donor Transplants with Post-Transplant Cyclophosphamide based prophylaxis.
Gooptu, M., et al. (2021) Blood [record in progress]
PICO SUMMARY

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SELECTED ARTICLES

Immune Reconstitution Following TCRaß/CD19-Depleted Hematopoietic Cell Transplantation for Hematologic Malignancy in Pediatric Patients.
Arnold, D. E., et al. (2021) Transplantation and Cellular Therapy 27(2):169.e1-169.e9

Excellent overall and chronic graft-versus-host-disease-free event-free survival in Fanconi anaemia patients undergoing matched related- and unrelated-donor bone marrow transplantation using alemtuzumab-Flu-Cy: the UK experience.
Bernard, F., et al. (2021) British Journal of Haematology [record in progress].

Multicenter Phase II Study on Haploidentical Bone Marrow Transplantation Using a Reduced-Intensity Conditioning Regimen and Posttransplantation Cyclophosphamide in Patients with Poor-Prognosis Lymphomas
Castagna, L. et al. (2021) Transplantation and Cellular Therapy27(4):328.e1-328.e6

Feasibility and Efficacy of CD45RA+ Depleted Donor Lymphocytes Infusion After Haploidentical Transplantation With Post-Transplantation Cyclophosphamide in Patients With Hematological Malignancies.
Castagna, L. et al. (2021) Transplantation and Cellular Therapy [record in progress]

Phase I Dose-Finding, Safety, and Tolerability Trial of Romiplostim to Improve Platelet Recovery After UCB Transplantation.
Christakopoulos, G. E., et al. (2021) Transplantation and Cellular Therapy [record in progress]

Second allogeneic haematopoietic cell transplantation using HLA-matched unrelated versus T-cell replete haploidentical donor and survival in relapsed acute myeloid leukaemia.
Kharfan-Dabaja, M. A., et al. (2021) British Journal of Haematology [record in progress].

Comparison of immune reconstitution between anti-T-lymphocyte globulin and post-transplant cyclophosphamide as acute graft-versus-host disease prophylaxis in allogeneic myeloablative peripheral blood stem cell transplantation.
Massoud, R., et al. (2021) Haematologica [record in progress].

Impact of Previously Unrecognized HLA Mismatches Using Ultrahigh Resolution Typing in Unrelated Donor Hematopoietic Cell Transplantation.
Mayor, N. P., et al. (2021) Journal of Clinical Oncology [record in progress].

Myeloablative versus Reduced-Intensity Conditioning for Hematopoietic Cell Transplantation in Acute Myelogenous Leukemia and Myelodysplastic Syndromes-Long-Term Follow-Up of the BMT CTN 0901 Clinical Trial
Scott, B. L., et al. (2021) Transplantation and Cellular Therapy [record in progress].

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