A couple
of weeks ago a colleague and I looked at e-HEMATimage case study 20.03, but
having technical issues we had to give up.
Seeing that
we’d got access to the answers today I had a look…
Well, what
can I say?... two of us looked, and two of us got the diff wrong. Many of what
we thought were neutrophils were actually eosinophils.
Poorly
stained eosinophils at that.
I suppose in retrospect there was something "iffy" about them - many of what were supposedly eosinophils I'd labelled as dysplatic neutrophils. But having missed the eosinophilia we plumped for a diagnosis of Myelodysplastic/myeloproliferative neoplasm (unclassifiable) rather than the consensus opinions of
1. Myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement (PDGFRA, PDGFRB, FGFR1 or PCM1-JAK2)
2. Chronic eosinophilic leukemia (WHO)
3. Acute myeloid leukemia with multilineage dysplasia (WHO)
For me the take-home message is look for shape in eosinophils, not just the colour. I've learned something here...
No comments:
Post a Comment