Liquid Plasma Acceptable for Severe Trauma Patients with Major Bleeding
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March 16, 2017
Recent studies have highlighted the importance of expeditious transfusion of plasma, platelets and red blood cells in a 1:1:1 ratio for severe trauma patients who are at risk of exsanguination. Since thawing plasma can be time-consuming, a recent study published in TRANSFUSION examined the hemostatic properties of thawed and liquid plasma over several days of [Read More]
Recent studies have highlighted the importance of expeditious transfusion of plasma, platelets and red blood cells in a 1:1:1 ratio for severe trauma patients who are at risk of exsanguination. Since thawing plasma can be time-consuming, a recent study published in TRANSFUSION examined the hemostatic properties of thawed and liquid plasma over several days of [Read More]
New PLASMIC Scoring System to Help Diagnose Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder caused by a lack of ADAMTS13 activity, which normally cleaves the von Willebrand factor. TTP patients have increased risk of thrombosis leading to blockage of blood flow to major organs. TTP is fatal if not treated quickly by plasma exchange. However, diagnosis of TTP by testing [Read More]
Administration of Fibrinogen Concentrate during Cardiac Surgery Does Not Significantly Reduce Blood Loss
Since fibrinogen plays a key role in hemostasis and it is rapidly depleted during cardiac surgery, many cardiac surgeons give fibrinogen to control bleeding during surgery for high-risk patients. The efficacy of this treatment, however, had not been previously confirmed in large, randomized clinical trials. A recent study in the Netherlands randomized 120 high-risk cardiac [Read More]
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