Asymptomatic Blood Donors
Have Zika Virus
January 19, 2017
As the Zika flavivirus (ZIKV) has spread throughout the Western Hemisphere, reports of severe side effects such as Guillain-Barre syndrome, acute neurological infections, and microcephaly have proliferated. Although the virus is usually transmitted by Aedes mosquitoes, reports of sexual, maternal-fetal, and transfusion-transmission have also been documented. In order to gain a better understanding of the [Read More]
January 19, 2017As the Zika flavivirus (ZIKV) has spread throughout the Western Hemisphere, reports of severe side effects such as Guillain-Barre syndrome, acute neurological infections, and microcephaly have proliferated. Although the virus is usually transmitted by Aedes mosquitoes, reports of sexual, maternal-fetal, and transfusion-transmission have also been documented. In order to gain a better understanding of the [Read More]
Improving Peripheral Blood Stem Cell Collection for Autologous Stem Cell Transplantation
January 11, 2017The City of Hope National Medical Center in California performs nearly 400 autologous stem cell transplants (ASCT) per year using mobilized peripheral blood stem cells (PBSCs), and they have had 99.2% successful PBSC collections (>2.0X106 CD34+ cells/kg) recently. Their approach to ASCT collection is multi-pronged—incorporating patient education and nurse coordinators, careful monitoring of collection yields [Read More]
KEL-Antigen Modulation is Important for Anti-KEL Immunoprophylaxis
January 5, 2017Rh immunoglobulin therapy has been used for more than 60 years to prevent alloimmunization in Rh-negative pregnant women carrying an Rh-positive fetus. The exact mechanism, however, of prevention remains unknown. Using a mouse model, Liu et al investigated the mechanism of alloimmunization to the KEL antigen on red blood cells (RBCs) and described the first [Read More]
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