The
nice people at “Transfusion News” sent their update today. All very
interesting, but I wish that science would make its mind up. Is convalescent
plasma worth using or not? Opinion seems to be changing on a weekly basis…
Covid-19 Convalescent Plasma Neutralizes Variants of Concern Including Omicron |
 March 9, 2022
Recent
omicron variants of the SARS-CoV-2 virus have at least 32 changes in
the spike protein relative to the original strain identified in Wuhan,
rendering many monoclonal antibodies (e.g., sotrovimab and tixagevimab)
developed against the Wuhan strain ineffective. Clinical trials,
however, have shown that COVID-19 convalescent plasma (CCP) transfusions
decrease the risk of hospitalization and mortality given to outpatients
and immunosuppressed individuals with COVID-19, respectively. [Read More]
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What is Liquid Plasma? with Chris Gresens |
 March 9, 2022 | BBGuy Podcast
CE
Episode! Plasma product names are confusing, but few are as
misunderstood as Liquid Plasma. Dr. Chris Gresens explains why LP might
be perfect for your transfusion service. [Listen Now]
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Enzymatic Treatment of Organ Allografts to Universal Blood Type O |
 March 2, 2022
Organ
transplant recipients with group O blood type often have to wait at
least twice as long as group A, B or AB recipients and have a 20%
greater risk of mortality while on the transplant waitlist. Similar to
RBCs, enzymatic removal of the terminal sugar epitope (α-galactose or
N-acetyl-galactosamine) on A and B antigen oligosaccharides would
convert these antigens to the universal group O blood type and expand
the compatible organ donor pool. [Read More]
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