The nice people at “Transfusion News”
sent their update today… One of the
things I find most frustrating about transfusion medicine is how opinion
changes so much. Back in the day whole blood was “the” thing to
transfuse... Then it wasn’t… Now… who knows?
Who does know? That’s why we do CPD – to keep
ourselves aware of who does know and what they know. Flippant? Maybe. But particularly
in the world of transfusion medicine it is important to keep up with current
thinking as opinion does change.
Platelet-Rich Plasma Injections Do Not Improve Ankle Osteoarthritis |
 November 17, 2021
Ankle
(tibiotalar) osteoarthritis affects approximately 3.4% of adults and is
associated with a reduced quality of life. Effective non-surgical
treatments are not available. Based on data from four small case
studies, autologous platelet-rich plasma (PRP) injections have been used
with the hope that growth factors released from α-granules in platelets
may modulate a regenerative response allowing affected tissue to heal. [Read More]
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Benefits and Harms of Whole Blood versus Component Blood Transfusions Remain Unclear |
 November 9, 2021
Transfusions
may be in the form of whole blood (WB) or blood components (BC). Blood
components include red blood cells, platelets, plasma, and
cryoprecipitate. Recently, studies have suggested that bleeding cardiac
surgery and trauma patients may benefit from WB transfusions. However,
storing WB solely for these patients could result in increased blood
wastage. [Read More]
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Red Blood Cells May Act as Immune Sentinels |
 November 1, 2021
Anucleated
red blood cells (RBCs) are essential for delivery of oxygen throughout
the body but have been considered immunologically inert. New evidence
recently published in Science Translational Medicine, however, suggests
that RBCs promote immune activation by binding to unmethylated, cell
free CpG nucleic acid fragments and promoting cytokine production.
Toll-like receptors play a key role in inflammation by identifying
nucleic acid fragments. [Read More]
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