8 November 2017 (Wednesday) - Differential Counting

Here’s an interesting discussion in the Facebook Hematology Interest Group…

What is your lab's policy regarding manual diffs on leukopenic oncology patients? Do you read them all? Have a lower limit to read? Report automated?

Personally I’d be inclined to report the automated diff from the analyser *if* one is obtained. And if one isn’t then do a manual diff *if* you can get a reliable diff. But what constitutes a reliable diff. I’ve seen slides in which there wasn’t more than a dozen white cells in the entire film.

I suppose the bottom line is that if there are too few cells to count then the patient is neutropenic; that is what the clinician wants to know.
The discussion in the article was interesting.

Some people don’t report diffs on Wbc <1.0
Some people do differentials on films made on buffy coats

… Really ?


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