The
nice people at Transfusion News sent their update today. Bearing in mind that
antibody titres have been pretty much the only way to judge how a potential
case of HDFN is faring, it’s a tad late in the day to cast doubt on the whole
thing, isn’t it?
High Variability in Antibody Titer Determination in Transfusion Medicine |
 March 2, 2023
Antibody levels are important for many aspects of clinical care from evaluating the incompatibility of transfusions and transplants to determining certain diagnoses such as hemolytic reactions. Although no gold standard exists to determine antibody levels, the majority of assays depend on titration and grading the strength of agglutination, which has been performed manually and is operator dependent. [Read more]
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Transfusion Transmission of Hepatitis A Virus during a Recent Epidemic in Europe |
 February 21, 2023
In most infections of hepatitis A (HAV), individuals have very mild symptoms or are asymptomatic. Although rare in the U.S., globally HAV causes about 1.4 million cases and usually spreads via fecal-oral routes; however, case reports have documented transmission by sexual contact and transfusion. An HAV outbreak occurred in Europe from 2016 to 2019, and researchers detected a rising number of HAV cases in Poland between mid-2017 and 2019. [Read more]
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