28 February 2022 (Monday) - Transfusion Evidence Alert Update


The nice people at the “Transfusion Evidence Alert” sent their update today. As always there was far too much to take in at one go, but it only comes out monthly…
The first article on transfusion thresholds was interesting… when should you give a transfusion… opinion varies so much, and has done so over the years…



Transfusion thresholds for guiding red blood cell transfusion.Carson, J.L., et al. (2021). The Cochrane Database of Systematic Reviews.PICO Summary available



Confirmation Bias Affects Estimation of Blood Loss and Amniotic Fluid Volume: A Randomized Simulation-Based Trial.Atallah, F., et al. (2021). American Journal of Perinatology.

Efficacy and Safety of Intravenous Iron Therapy for Treating Anaemia in Critically ill Adults: A Rapid Systematic Review With Meta-Analysis.Geneen, L.J., et al. (2021). Transfusion Medicine Reviews. [Record in progress]

Red blood cell transfusion in myelodysplastic syndromes: A systematic review.Kaka, S., et al. (2021). Transfusion Medicine.

Preemptive antifibrinolysis: its role and efficacy in hip-fracture patients undergoing total hip arthroplasty.Liu, J., et al. (2021). The Journal of Arthroplasty. [Record in progress]

Tranexamic Acid for Prevention of Hemorrhage in Elective Repeat Cesarean Delivery - A Randomized Study.Ogunkua, O.T., et al. (2022). American Journal of Obstetrics & Gynecology.  [Record in progress]

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia.Peffault de Latour, R., et al. (2022). The New England Journal of Medicine.

Iron chelation therapy in patients with low- to intermediate-risk myelodysplastic syndrome: A systematic review and meta-analysis.Yang, S., et al. (2021). British Journal of Haematology. [Record in progress]

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