July 20, 2017
Platelet reactivity to agonists has been shown to be different between donors yet consistent within the same individual. Researchers in the United Kingdom hypothesized that more active platelets would be cleared from circulation resulting in lower platelet counts in transfused patients. In order to test this hypothesis, donors with high and low responding platelets were [Read More]
Reversal of Direct Oral Anticoagulants: a Systematic Review
July 12, 2017
Direct oral anticoagulants (DOACs), such as dabigatran, rivaroxaban, apixaban, and edoxaban, have many advantages over warfarin for treating patients with thromboembolic issues. DOACs may be reversed by agents such as activated and inactivated prothrombin complex concentrates (PCCs), idarucizumab and andexanet alfa. In order to determine the safety and efficacy of reversing DOACs in bleeding emergencies [Read More]
July 24, 2017 | BBGuy Podcast
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