Döhle
bodies are
light blue-gray, oval basophilic inclusions in the cytoplasm of neutrophils.
They measure 1-3 µm in diameter. Not much is known about their formation,
but they are thought to be remnants of the rough endoplasmic reticulum.
They
are named after German pathologist, Karl Gottfried Paul Döhle
They
are often present in conjunction with toxic granulation. However, it
has been found that certain healthy individuals may have persistent Döhle
bodies found in neutrophils
They
are seen in:
- Burns
- Infections
- Physical trauma
- Neoplastic diseases
- Fanconi syndrome
- May-Hegglin
anomaly
- Chédiak-Steinbrinck-Higashi’s
syndrome
- leukemoid
reaction
They aren’t seen that often, but today….
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