I
found this link today
via Facebook (of all places). The Blood
Bank Guy gave a very informative article about the G-antigen. I found it rather
useful; I can remember a case of this a while ago… I could not remember any of
the details. It was a rather good refresher.
At
the risk of blatantly plagiarising here are the salient points
- G is an antigen present whenever D and/or C is present
- Anti-G will react against D+ RBCs, C + RBCs, and D+C+ RBCs
- Anti-G is pretty easy to manage in most transfusion patients: Almost all D-negative RBCs will be compatible
- Identifying anti-G is most important for prenatal patients and will make all the difference in getting such a patient the RhIg they need, or saving them from an RhIg dose if not needed
- Teasing out a patient’s antibody specificity is time-consuming, but is valuable for ensuring RhIg is used when indicated, and not unnecessarily
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