Here’s an interesting article: A 49-year-old woman presented immediately on return from a 2-week visit to Tanzania
· Malaise
· Fatigue
· Arthralgia
· high fever (39°C).
Physical examination revealed signs of an arthropod bite on the neck.
Hepatosplenomegaly and lymphadenopathy were absent. Blood analysis showed
· leukopenia (2.3 × 109/L)
· thrombocytopenia (55 × 109/L)
· low prothrombin index expressed as a percentage (66%)
· increased lactate dehydrogenase (622 IU/L; normal, 250-450 IU/L), aspartate aminotransferase: 159 IU/L; normal, 5-40 IU/L
· alanine aminotransferase: 207 IU/L; normal, 5-40 IU/L.
· Cerebrospinal analysis and an abdominal computed tomography scan were normal.
The peripheral blood film was diagnostic for trypanosome infection, showing the presence of extracellular flagellated parasites
I
found this particularly relevant as I’d missed these in a recent NEQAS survey…
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