20 November 2023 (Monday) - Platelet Satellites

I saw some platelet satellites today. We often see platelets clumping in EDTA (at least once every day, but seeing them satellite around neutrophils is a relatively rare occurrence. Interestingly (and something I didn’t realise) is that demonstrably the platelets don’t form satellites around every neutrophil.
I wonder why not.
Anyway, here’s a couple of references on the matter:
The second reference says “The clinical importance of this phenomenon is that in some cases it may result in spurious thrombocytopenia or pseudothrombocytopenia leading to further unnecessary investigations. Thus, recognition of this in vitro phenomenon only re-emphasizes the necessity of age old practice of peripheral blood film examination".
Written by an old-timer like me!!!


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