25 June 2023 (Sunday) - Transfusion Evidence Alert update


The nice people at Transfusion Evidence Alert sent their update today. I can’t pretend to have done more than quickly skimmed it as there was so much, but some of it has stuck. Interestingly the phrase “cost effective” appeared several times…


Cost-effectiveness of cell salvage in trauma blood transfusions.Beeton, G., et al. (2023). The American Surgeon. [Record in progress].

Systematic review highlights high risk of bias of clinical prediction models for blood transfusion in patients undergoing elective surgery.Dhiman, P., et al. (2023). Journal of Clinical Epidemiology. [Record in progress]. 

Prehospital tranexamic acid is associated with a dose-dependent decrease in syndecan-1 after trauma: A secondary analysis of a prospective randomized trial.Gruen, D.S., et al. (2023). The Journal of Trauma and Acute Care Surgery. [Record in progress].Convalescent plasma for people with COVID-19: a living systematic review.Iannizzi, C., et al. (2023). The Cochrane Database of Systematic Reviews.

Prophylactic epinephrine attenuates severe bleeding in lung transplantation patients undergoing transbronchial lung biopsy: Results of the PROPHET randomized trial.Kalchiem-Dekel, O., et al. (2023). The Journal of Heart and Lung Transplantation. [Record in progress].

Efficacy of plasmapheresis in neutropenic patients suffering from cytokine storm because of severe COVID-19 infection.Sadeghi, A., et al. (2023). Blood Research. [Record in progress].

Platelet transfusion before CVC placement in patients with thrombocytopenia.Van Baarle, F.L.F., et al. (2023). The New England Journal of Medicine.

Cost-effectiveness of thrombopoietin mimetics in patients with thrombocytopenia: a systematic review.Van Remoortel, H., et al. (2023). PharmacoEconomics. [Record in progress].

Efficacy of eltrombopag with immunosuppressive therapy versus immunosuppressive therapy alone on severe aplastic anaemia: a systematic review and meta-analysis.Zhang, S., et al. (2023). Clinical Drug Investigation.


Randomized trial of early detection and treatment of postpartum hemorrhage.Gallos, I., et al. (2023). The New England Journal of Medicine. [Record in progress].PICO Summary available


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