20 August 2019 (Tuesday) - Stem Cell Evidence Alert

I subscribe to the Stem Cell Evidence Alert. Like quite a few of the mailing lists I follow it doesn’t come up with amazingly relevant and directly useful stuff, but background reading is always useful…

Article of the Month: Addition of sirolimus to standard cyclosporine plus mycophenolate mofetil-based graft-versus-host disease prophylaxis for patients after unrelated non-myeloablative haemopoietic stem cell transplantation: a multicentre, randomised, phase 3 trial Sandmaier, B. M., Kornblit, B., et al.  The Lancet. Haematology 2019 PICO Summary available

Selected new publications, including PICO Summaries! Transplantation in children and adolescents with acute lymphoblastic leukemia from a matched donor versus an hla-identical sibling: Is the outcome comparable? Results from the international bfm all sct 2007 study Balduzzi, A., Dalle, J. H., et al., Biology of blood and marrow transplantation 2019 Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial Bastidas, A., de la Serna, J., et al. JAMA 2019 Selection of Unrelated Donors and Cord Blood Units for Hematopoietic Cell Transplantation: Guidelines from NMDP/CIBMTR Dehn, J., Spellman, S., et al. Blood 2019. Tandem autologous stem cell transplantation improves outcome in newly diagnosed multiple myeloma with extramedullary disease and high-risk cytogenetics: a study from the Chronic Malignancies Working Party of EBMT Gagelmann, N., Eikema, D. J., et al. Biology of blood and marrow transplantation 2019 Effect of sirolimus on immune reconstitution following myeloablative allogeneic stem-cell transplantation: An ancillary analysis of a randomized controlled trial comparing Tacrolimus/Sirolimus with Tacrolimus/Methotrexate (Blood and Marrow Transplant Clinical Trials Network/BMT CTN 0402) Gooptu, M., Kim, H. T., et al. Biology of blood and marrow transplantation 2019. Comparison of tacrolimus and cyclosporine combined with methotrexate for graft-versus-host disease prophylaxis after allogeneic hematopoietic cell transplantation Huang, B., Lin, X., et all. Transplantation 2019. Survival Outcomes of Allogeneic Hematopoietic Cell Transplants with EBV positive or EBV negative Post Transplant Lymphoproliferative Disorder (PTLD), A CIBMTR Study Naik, S., Riches, M., et al. Transplant infectious disease 2019. Immune recovery after in vivo T-cell depletion myeloablative conditioning hematopoietic stem cell transplantation in severe beta-thalassemia children Qin, F., Shi, L., et al. European journal of haematology 2019.