Higher Hematocrit Levels Are Associated with Increased Thrombosis Risk and Reduced Bleeding
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May 10, 2017
A growing number of recent studies have observed an association between elevated hematocrit levels and thrombosis. However, the mechanism behind this pathway has remained elusive. A recent study induced an elevation of hematocrit levels in otherwise healthy mice to tease apart the etiology of the thrombosis formation under increased RBC levels. Compared with control mice [Read More]
A growing number of recent studies have observed an association between elevated hematocrit levels and thrombosis. However, the mechanism behind this pathway has remained elusive. A recent study induced an elevation of hematocrit levels in otherwise healthy mice to tease apart the etiology of the thrombosis formation under increased RBC levels. Compared with control mice [Read More]
Early Administration of Tranexamic Acid Reduces Maternal Deaths Due to Bleeding
Administration of tranexamic acid, an antifibrinolytic drug, has been shown to reduce bleeding in trauma and surgery patients. The results of the WOMAN (World Maternal Antifibrinolytic) trial recently published in The Lancet show that tranexamic acid also reduces the risk of maternal death due to bleeding. Between 2010 and 2016, over 20,000 women with post-partum [Read More]
Transfusion of Red Blood Cells from Younger Donors Is Not Associated with Improved Survival
Animal models suggest that blood from younger donors may provide revitalizing benefits, but findings from observational cohort studies on this topic have been inconsistent. Investigators in Scandinavia recently performed a retrospective cohort study following 968,264 red blood cell (RBC) transfusion recipients for 10 years. Since multiple transfusions can confound results, researchers used multiple approaches to [Read More]
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