Here’s
something new to me. Two references on the matter – Pubmed and Blood – both respected
publications.
Apparently
green neutrophil inclusions have been reported as a sign of impending patient
death. In a series of twenty patients in whom green inclusions were identified
in neutrophils or monocytes thirteen died within days of the detection of the
inclusions.
A
common feature to almost all patients was ischaemic or hypoxic hepatitis which,
in fatal cases, was associated with lactic acidosis.
What
are the inclusions?
Light
and electron microscopy indicated that the inclusions were lipid-rich, probably
derived from lipofuscin-like material released from necrotic liver parenchymal
cells.
It
is recommended that that the detection of green inclusions, referred to as 'critical green inclusions', is
acknowledged and reported by laboratories and correlated with clinical
findings.
I’ve
never seen them…
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