This is (supposed to be) a reflective diary by a (not very) anonymous biomedical scientist who works somewhere in the south of England. One day this diary may well be submitted to the Health and Care Professions Council as evidence of ongoing continual professional development....
The nice people at Oncology Central sent their update today. You can read it by clicking here. I can’t pretend that I hung on every word. There’s no denying that much of it went over my head. But some of it made some sense, and if only one percent has filtered through my thick head, that’s one per cent more than if I hadn’t had a look at it, isn’t it?
The nice
people at the Transfusion Evidence Library sent their update today… or their “quarterly
Transfusion Evidence Round-Up” to be precise…
All good
stuff…
Top Article
The efficacy of Roxadustat for the treatment of anemia in dialysis dependent chronic kidney disease patients: an updated systematic review and meta-analysis of randomized clinical trials.Abdelazeem, B., et al. (2021). Annals of Translational Medicine.PICO SUMMARY
Selected Articles
The efficacy and safety of roxadustat for the treatment of anemia in non-dialysis dependent chronic kidney disease patients: An updated systematic review and meta-analysis of randomized clinical trials.Abdelazeem, B., et al. (2022). PloS One.
Thrombopoietin receptor agonists and rituximab for treatment of pediatric immune thrombocytopenia: A systematic review and meta-analysis of prospective clinical trials.Ayad, N., Grace, R.F., and Al-Samkari, H., (2021). Pediatric Blood & Cancer.
Intravenous Iron Supplementation for the Treatment of Chemotherapy-Induced Anemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Buchrits, S., et al. (2022). Journal of Clinical Medicine.
Comparative Efficacy and Safety of Thrombopoietin Receptor Agonists in Adults With Thrombocytopenia: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials.Deng, J., et al. (2021). Frontiers in Pharmacology.
Promoting awareness of donation-related iron depletion among high risk blood donors.France, J.L., et al. (2021). Transfusion.
Efficacy and Safety of Daprodustat Vs rhEPO for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis.Fu, Z., et al. (2022). Frontiers in Pharmacology.
Serum or plasma ferritin concentration as an index of iron deficiency and overload.Garcia-Casal, M.N., et al. (2021). The Cochrane Database of Systematic Reviews.
Sustained low-dose prophylactic early erythropoietin for improvement of neurological outcomes in preterm infants: A systematic review and meta-analysis.Liang, L., et al. (2021). Journal of Affective Disorders.
Comparative efficacy of 19 drug therapies for patients with idiopathic thrombocytopenic purpura: a multiple-treatments network meta-analysis.Zhou, H., et al. (2022). Annals of Hematology.
46738 - A fifty-five year-old woman in theatre requiring group and saveShe grouped as O Rh(D) Positive with a negative antibody screen.59043 - an eighty year old chap in A&E al;so requiring group and save.The date of birth on the sample was wrong (27-7-1990 compared with 1-1-42) so I rejected it.
A
question in the Facebook Haematology Interest Group: “Can I ask how others deal with clumped platelets in EDTA”. There was
an interesting discussion… I say “interesting
discussion”: most of the contributors just repeated what others had said, and
of the rest the majority were showing their ignorance, but a couple of useful
links appeared:
https://www.captodayonline.com/qa-column-1114/
together
with the tip to replace plasma with warmed saline. There was also talk of “thromboexact
tubes” which use magnesium sulphate
as an anticoagulant.
Time for a
BTLP-TACT exercise. I was presented with one case; a sixty-eight year-old chap
in the out-patients department requiring group & save for a hip
replacement.
He grouped
as O Rh(D) Positive with a negative
antibody screen.
I got the green
light.
