6 July 2018 (Friday) - Cooked

Here’s an interesting case. I walked in to a night shift to be told about an amazing unexpected thrombocythaemia…

I’ve written it up as a Google document.


1 July 2018 (Sunday) - Morphology

The other day I mentioned about a discussion on the Facebook Haematology Interest Group about standardisation of blood film morphology.
Here’s a far more readable article on the subject…


30 June 2018 (Saturday) - Back in the Day...

A question appeared on the Facebook Haematology Interest Group “Is there any lab still using The Lee and White Test for Coagulation Time?

It rang a vague bell… I had to look it up. Whole blood clotting time… Does anyone still do it? I can remember people laughing at it nearly forty years ago.
In the subsequent discussion it turned out that some people still do perform that test.
I wonder why…


27 June 2018 (Wednesday) - Morphology

Someone posted a flippant comment on the Facebook Haematology Interest Group about “squashed duck” cells. One of the more normal people on that group took umbrage with the “non-standardised” morphological comments being used.
But after all the sighs and “get a life” comments had been made, this article emerged from the dust.


It makes for dry reading, but some sort of consistency in the reporting of blood film morphology is really needed.

27 June 2018 (Wednesday) - Transfusion News Update

The nice people at Transfusion News sent out their update today...



Perioperative RBC Transfusions Linked to Increased Risk of Blood Clots
June 20, 2018
Venous thromboembolism (VTE) is associated with 5-10% of all hospital deaths, or about 100,000 to 200,000 deaths each year in the United States. However, many of these deaths may be preventable. In order to gain a better understanding of the association between VTE and RBC transfusions, researchers used data gathered [Read More]
Patient Blood Management: What Are You Missing? with Aryeh Shander
June 25, 2018 | BBGuy Podcast
Modified transfusion thresholds? Got 'em! "Why give 2 when 1 will do?" Sure. But many patients are in trouble even before they arrive! Dr. Shander explains why preoperative anemia is a HUGE issue. [Listen Now]

26 June 2018 (Tuesday) - Lymphoma in Myelofibrosis?

The British Society of Haematology sent out an email telling me of an article outlining a possible increase in lymphoma risk for people taking Janus kinase (JAK) inhibitors to treat myelofibrosis.


Something to bear in mind when looking down the microscope at all those already odd-looking cells…

25 June 2018 (Monday) - Extra Medullary Haemopoesis


The nice people at Lablogatory sent this article today – two apparently dissimilar cases, but both with a common factor – extra-medullary haemopoesis.
I must admit that isn’t something to which I’ve given a lot of thought for some time.

This is why we do CPD…


24 June 2018 (Sunday) - And There's More...

Here’s food for thought. Plasmodium cynomolgi has been identified in humans. That is now eight species of malaria known to infect humans.
It was only four back in the day…


Since this latest discovery has a range somewhat more extensive than that of those previously known to be a threat to humans, I can’t help but wonder how many people will be infected before the maps finally get re-drawn…

22 June 2018 (Friday) - How True...

Here’s something I read on the Facebook Hematology Interest Group; It struck me as incredibly wise, incredibly true, and explains why after thirty years of looking down a microscope I am still hesitant about the thing…


“"Don't complain if the cell doesn't look like in the atlas, you don't look like your profile photo either!!!!


22 June 2018 (Friday) - Transfusion Evidence Alert Update

The nice people at “Transfusion Evidence Alert” sent their update today:

Article of the Month (June 2018)

Selected new publications
Measuring coagulation in burns: an evidence-based systematic review
Marsden NJ, Van M, Dean S, et al. Scars, Burns & Healing 2018. Free Full Text



 

21 June 2018 (Thursday) - Pathology Outlines Update


The nice people at “pathology outlines” sent their update today. It would be nice if it was as a web page rather than all on an email, but I’m grateful for anything I can get.


There wasn’t *loads* of import in this email, but they have a blog and a Facebook page. I’ve subscribed to both, and am hoping for the best…


19 June 2018 (Tuesday) - Oncologist Update


The nice people at “The Oncologist” sent their update today. As always it isn’t of immediate direct impact to what I do, but it helps keep me up to date on what is going on in what is “behind the scenes” in my world.

I’m grateful for these updates…

19 June 2018 (Tuesday) - Case Study



The nice people at Lablogatory sent a case study today. It was about someone with malaria rolling up at a hospital. It was not earth-shattering, or ground-breaking. But it was a true-life description of something  that actually happened.

This is the sort of thing form which I learn…

19 June 2018 (Tuesday) - BTLP - TACT

I had my appraisal today. As well as building up experience with the new works automation and helping with cross-site harmonisation, I’m to be a guinea-pig for the BTLP-TACT wotsit.


I’ve heard great things about the BTLP-TACT – I’m looking forward to getting involved with it.

18 June 2018 (Monday) - The Lewis Blood Group System



Here’s an interesting little article form the nice people at Lablogatory about the Lewis blood group system and how it can be a nuisance during a pregnancy




16 June 2018 (Saturday) - On-Line Atlas

One of my (many) on-line projects is an unashamed attempt to create the ultimate and definitive on-line Atlas of Haematology; an atlas so immensely impressive that all others will pale into insignificance when compared with it…
Is that *such* an ambition?

About eight years ago I made a start on one, and rather forgot all about it. You can see it by clicking here. There’s no denying that it has still got a little way to go before being heralded as the ultimate and definitive on-line Atlas of Haematology, but it is a start…

This week we had two interesting cases in work; a new case of AML, and a hypochromic microcytic anaemia with basophilic stippling.
I’ve added those two cases onto this atlas.

Seriously though… is this atlas worth continuing?
On the one hand there are endless case studies on-line which are presented far better.
On the other hand these are cases that *I*  have personally experienced.

I’ll look to beefing the atlas up a little…


15 June 2018 (Friday) - Thyroid

The other day I subscribed to Pathology Outlines dot com. They sent their first missive today. It was an update on what’s new in thyroid medicine and disease.

Maybe not as directly relevant to my day to day practice as some stuff, but nonetheless it is interesting. I shall continue this subscription and hope for the best…

14 June 2018 (Thursday) - Updated Transfusion Guideleines

The Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee sent me an email. They’ve updated some of their guidelines:



This is another mailing llist to which I shall remain subscribed. This is “proper” CPD – directly relevant to what I do…



13 June 2018 (Wednesday) - Safety


Another mailing list of which I’ve remained a member is the one from the nice people at “Lablogatory”. Today’s missive was focussed on safety in the laboratory.
It is easy to be flippant, but when you think exactly what it is we do (we examine and investigate body fluids of seriously ill people), personal safety is something which *must* be paramount in our minds.


You can read the article they sent by clicking here. It was interesting… but just lately the nice people at Lablogatory seem to have taken a new direction and are becoming very “strange-school-of-management” focussed. “Gather a team of “Safety Avengers” “ ?  Seriously? 

13 June 2018 (Wednesday) - Transfusion News Update

The Transfusion News email arrived in my inbox this morning. Having unsubscribed from some rather irrelevant mailing lists earlier in the week, Transfusion News remains to be useful to me. Particularly the podcast from the Blood Bank Guy…

Transfusion Dependence for Leukemia Patients Shortens Hospice Stay
June 6, 2018
Approximately 25,000 individuals in the United States die annually from leukemia. These individuals often require transfusions; however, hematologic oncologists have differing beliefs about transfusions near the end of life, which may delay or hinder these patients from enrolling in hospice. In order to gain a better understanding, researchers examined data [Read More]
Typing Blood Group Variants from Whole-Genome Sequencing Data
May 30, 2018
Serological testing for ABO and RhD blood group compatibility has been standard practice for at least 60 years. ABO and RhD blood group antigen matching between blood donors and recipients decreases the risk of hemolytic transfusion reactions, alloimmunization, and other serious complications including death. However, more than 300 other RBC [Read More]
Product Choice and Compatibility Testing with Sue Johnson
June 12, 2018 | BBGuy Podcast
Sue Johnson finishes the Pretransfusion Testing discussion with how to select products and test them for compatibility. She also tackles six cases showing “classic” issues in pretransfusion testing. [Listen Now]

11 June 2018 (Monday) - Reviewing Mailing Lists


A good way to do CPD is to have someone else put in the effort for you, and so periodically I scan the Internet looking for mailing lists to join.

I’ve joined the ones at http://www.pathologyoutlines.com  and the European School of Hematology – I’m hoping these will pay dividends.
However a little while ago I joined “Daily Biomedical Discovery” and “Bioanalysis Zone”– today I unsubscribed from them. Neither proved useful.

Being a naturally lazy person I’ve found out that being truly lazy takes a little effort. What’s the point of having endless emails to plough through if not every single one is worth having?

10 June 2018 (Sunday) - Richter Transformation


An interesting case appeared in the Hematology Interest Group Facebook page today. You can see it by clicking here. It is a case of Richter transformation.

Richter transformation – it rings a vague bell… CPD is invaluable sometimes for keeping me up to date. After all, that’s why we all do it…