This is (supposed to be) a reflective diary by a (not very) anonymous biomedical scientist who works somewhere in the south of England. One day this diary may well be submitted to the Health and Care Professions Council as evidence of ongoing continual professional development....
11 December 2025 (Thursday) - BTLP-TACT Exercise
Having had another email about how I’m
not doing enough BTLP-TACT exercises, I suppose I ought to do one…
I was presented with two cases:
18493 – a seventy-two year-old chap who is tired all the time who needs a group and save.
He grouped as O Rh(D) Positive with a negative antibody screen.
08556 – an eighty-four year-old chap in A&E needing four units of blood for a GI bleed.He also grouped as O Rh(D) Positive but with antibody screen positive in cell 2. I performed antibody panels. The IAT and enzyme panels were positive in cells 3 and 5 corresponding with anti-E.I issued four units of O Rh(D) Positive E-negative blood.
I got it right…
10 December 2025 (Wednesday) - Unexplained (?) Neutropenia
I had a case of unexpected neutropenia
today. The given diagnosis was “MS on Lemtrada”.
Lemtrada is a brand name for alemtuzumab,
a known side effect of which is neutropenia.
Rather than laying an egg and running
screaming to the consultant, I didn’t end up setting off a totally unnecessary red
alert.
Here’s an article on the
matter.
I learned something today.
8 December 2025 (Monday) - BTLP-TACT Exercise
Time for another BTLP-TACT
exercise. I was given two cases:
14406 – a forty-nine year-old woman with a ruptured ectopic pregnancy needing six units of blood tomorrow (?).She grouped as O Rh(D) Positive with a negative antibody screen. I selected six units of O Rh(D) Positive K Negative blood.03592 – a thirty-two year-old woman in the ante-natal clinic needing group and save.She grouped as O Rh(D) Positive with antibody screen positive in cell 2. I performed antibody panels. The enzyme and IAT panels were positive in cells 2 and 6 corresponding with anti-K
8 December 2025 (Monday) - Learning Monday
It’s aplastic anaemia…
In hypocellular MDS you’d expect to see blasts in the bone marrow.
Mycobacterial infection doesn’t result in hypocellularity.
Haemophagocytosis wasn’t seen.
It’s not pure red cell aplasia as other cell lines are affected.
In hypocellular MDS you’d expect to see blasts in the bone marrow.
Mycobacterial infection doesn’t result in hypocellularity.
Haemophagocytosis wasn’t seen.
It’s not pure red cell aplasia as other cell lines are affected.
7 December 2025 (Sunday) - Parvovirus
Parvovirus infection can seriously adversely affect erythropoiesis. I didn’t realise that. One lives and learns… through doing CPD.
Here’s an article
on the matter.
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