10 January 2019 (Thursday) -Transfusion News email


The Transfusion News email came today. My last two posts were grumbles. This one - not so. Ironically the works IT people have blocked the web domain used by the nice people at Transfusion News…


Locus on Chromosome 5 Associated with Alloimmunization
January 9, 2019
Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with SCD do not form alloantibodies even after several transfusions, other “responder” SCD patients are more susceptible. While pro-inflammatory conditions have been shown to increase the risk for [Read More]
The “Transfusion Medicine Question of the Day” is now available in Spanish for the first time. “Question of the Day” is a free interactive resource that helps professionals in transfusion medicine stay up to date on vital information in their field. [Read More]
Restrictive RBC Transfusions Safe for Patients Long-Term
January 2, 2019
Several randomized clinical trials demonstrated restrictive RBC transfusion approaches are safe for patients over the short-term. Many patients with moderate anemia (hemoglobin between 7 g/dL and 10 g/dL) no longer receive RBC transfusions, and the long-term consequences of restrictive RBC transfusions have not [Read More]
Whole Blood Transfusions on the Battlefield
December 26, 2018
Uncontrolled hemorrhage is life threatening for trauma victims, and transfusion of blood products along with hemorrhage control is critical for patient survival. Whole blood (WB) transfusions have been used in the military setting since [Read More]
Electronic Scanning of Patient Wristbands Reduces Chance of ABO-Incompatible Transfusions
December 19, 2018
ABO-incompatible transfusions can be life-threatening to patients and are often attributable to human errors. Wrong blood in tube (WBIT) errors lead to an ABO-incompatible transfusion about 1% of the time, and these errors are preventable. WBIT errors occur when [Read More]

10 January 2019 (Thursday) - IBMS Newsletter


The IBMS newsletter came today. Yesterday I was whinging about how I’ve signed up to so many mailing lists and how few of them are of any actual use to me.

I’m not going to run down my own professional body, but perhaps their missives might be more useful if they had a few less generic ones, and a few more discipline-specific ones.

9 January 2019 (Wednesday) - The Oncologist Newsletter



The Oncologist” newsletter appeared in my inbox today. I won’t lie. I perused it briefly and then pressed the “delete” button. The thing is useful... but is really only of peripheral interest. None of the articles caught my eye.

This newsletter isn’t alone. I’ve signed up to a *lot* of mailing lists which aren’t really much use to me. The “bioanalysis zone” is one such, as is the regular update from NHS England and loads of others. They keep me vaguely of general health-related  matters but I can’t help but wonder just how much benefit I get from them. Would the time I spend deciding not to bother with each of these snippets be better spent concentrating on stuff which *is* useful?

Perhaps I need to revisit exactly just what I’ve signed up to?

8 January 2019 (Tuesday) - Blood Film NEQAS


I looked at the December NEQAS films on 12 December... the information given was rather lacking as it usually is.

The results came back on today - I did good.

1808 BF1

Left shifted neutrophilia   (3)/(5)
Metamyelocytes
myelocytes​                      (2)
Thrombocytopenia          (1)

?? reactive  ? CML          (CML)

1808 BF2

Lymphocytosis (1)
Smear cells​      (6)
Sezary cells     (5)
Hypochromia   (4)
Pencil cells      (10)

?? Sezary       (Sezary syndrome)


That’s four out of the top five comments on 1808 BF1 and five out of the top ten comments on 1808 BF2, and both conditions recognised correctly.

7 January 2019 (Tuesday) - An Algorithm



Something from the Facebook Haematology Interest Group - a CBC algorithm combined with immature platelet fraction is able to identify JAK2 V617F mutationpositive polycythaemia vera patients.

There was a lot of “blah blah” on the original post on Facebook. Science can often be dry “blah blah”. No one picked up on the fact tha this is about an algorithm based on the very numbers our analysers churn out every day in thousands. Would it take much effort to run this algorithm with every blood count? After all this is why we do screening, isn’t it?

7 January 2019 (Tuesday) - A Reflection on a Career in EQA

Here's something thought-provking...

7 January 2019 (Monday) - Segmented or Band?


An interesting post Medical Laboratory Science group over on Facebook: “So I got written up recently for over calling bands because the NICU uses the IT ratio to determine if the babies need continued antibiotic treatment. Apparently the top one here would actually be considered a seg, according to my hospital. I don't recall learning this in school. Do you guys?

Band” neutrophils as opposed to “segmented” neutrophils… ? Both are American terms, aren’t they? The subsequent discussion was interesting. Over here in the UK we’d never mess about trying to differentiate between segmented and band forms. We’d just report “left shift” and leave it at that.
Wouldn’t we…?