tag:blogger.com,1999:blog-56614718697888499462024-03-17T21:34:41.014+00:00A Dull Day At Work...?This is (supposed to be) a reflective diary by a (not very) anonymous biomedical scientist who works somewhere in the south of England.
One day this diary may well be submitted to the Health and Care Professions Council as evidence of ongoing continual professional development....Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.comBlogger2411125tag:blogger.com,1999:blog-5661471869788849946.post-42957398270575321722024-03-17T21:33:00.009+00:002024-03-17T21:33:45.119+00:0017 March 2024 (Sunday) - BTLP-TACT Exercise<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgrO7t5mfjA2vIOZ7MZULph6dMeWe_3poh8hKclwjzBWOGNqJOsPekNB1EZWldRoTkFiY_UdjCqKoMpzY_jL8G0JXtGRHdLihIRQfBqCWduMco7NQsCvwlxMJU0LJjH1gRNqo8jBipXwpaQ2hlBq1qiTV2MMKMlJzoQTDxUk1m1t5gLIRNuUag5BaTheAc/s700/btlptact.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="248" data-original-width="700" height="141" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgrO7t5mfjA2vIOZ7MZULph6dMeWe_3poh8hKclwjzBWOGNqJOsPekNB1EZWldRoTkFiY_UdjCqKoMpzY_jL8G0JXtGRHdLihIRQfBqCWduMco7NQsCvwlxMJU0LJjH1gRNqo8jBipXwpaQ2hlBq1qiTV2MMKMlJzoQTDxUk1m1t5gLIRNuUag5BaTheAc/w400-h141/btlptact.jpg" width="400" /></a></div><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif;">Time for another BTLP-TACT exercise. The
software gave me two cases:</span></div><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span></div><p></p><blockquote style="border: none; margin: 0px 0px 0px 40px; padding: 0px; text-align: left;"><p></p><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"><b><u>38895</u></b> – a sixty-nine year-old woman needing
group and save. She grouped as A Rh(D) Positive with antibody screen positive
in all three cells.</div></span></div><p></p><p></p><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I requested panels.</div></span></div><p></p><p></p><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">The IAT panel was positive in cells 1, 3,
4, 6, 7, 9 and 10 - possible anti-Cw anti-Lu(a)
anti-Fy(a) anti-Jk(a)</div></span></div><p></p><p></p><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">The enzyme panel was positive in cells
1, 3, 4, 6, 7 - possible anti-Cw anti-Jk(a)</div></span></div><p></p><p></p><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">So – this patient has anti-Fy(a) and anti-Jk(a)
but anti-Cw cannot be excluded. </div></span></div><p></p><p></p><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"><b><u>17765</u></b> – a seventy-four year-old woman
also needing group and save. She too grouped as A Rh(D) Positive with a
negative antibody screen.</div></span></div><p></p></blockquote><p></p><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I got the green light.</div></span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-42129759362794827292024-03-17T21:08:00.001+00:002024-03-17T21:08:06.949+00:0014 March 2024 (Thursday) - Transfusion Evidence Alert Update<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjDJS2T5ofjzgxdO6PY32DySZX1PBPlFHL5-CmMz-N3_GBSzZT8hetd-Mfz_XyCRjmkdSufGGTk7h1nwy_mpwhQzOvc_wkgcDsAmM_lKVcWbJHbepgwoV04wuyQQdV1-gy61AjmQvUlyN6EjKBxTTIqR-zDiNtj_xdCMsIIPLQF_OO4OUQUJfLgDL1x_1M/s634/tea.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="137" data-original-width="634" height="86" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjDJS2T5ofjzgxdO6PY32DySZX1PBPlFHL5-CmMz-N3_GBSzZT8hetd-Mfz_XyCRjmkdSufGGTk7h1nwy_mpwhQzOvc_wkgcDsAmM_lKVcWbJHbepgwoV04wuyQQdV1-gy61AjmQvUlyN6EjKBxTTIqR-zDiNtj_xdCMsIIPLQF_OO4OUQUJfLgDL1x_1M/w400-h86/tea.jpg" width="400" /></a></div><p></p><p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: Arial, sans-serif;">The Transfusion Evidence Library update
arrived today. Bearing World Kidney Day in mind, the focus was on renal
involvement:<span style="font-size: 12pt;"><o:p></o:p></span></span></p><p> <strong style="background-color: white; color: inherit; font-family: inherit; font-size: 17px; font-style: inherit; font-variant-caps: inherit; font-variant-ligatures: inherit; line-height: inherit;"><span style="border: 0px; color: rgb(220, 53, 69) !important; font: inherit; margin: 0px; padding: 0px; text-decoration: inherit; vertical-align: baseline;">Top article</span></strong></p><div style="background-color: white; border: 0px; color: #565656; font-family: sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 14px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; margin: 0px 20px; padding: 0px; vertical-align: baseline;"><div style="border: 0px; color: inherit; font: inherit; margin: 0px; padding: 0px; vertical-align: middle;"><p style="line-height: inherit; margin-bottom: 20px; margin-top: 0px;"><a data-auth="Verified" data-linkindex="6" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-i%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242897681%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=%2BwNDsMzN3iKVxk%2Fii1M79HCeF9W%2FHYTBOchOQxVNI7A%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-i/" rel="noopener noreferrer" shash="FdkrOSDdlgVXOqD1fKSxM2Kz41RgxrQrog4QDYMLKGBGOyT8rKD85dAxi49tJUQMG0sU3J73TnG7CaHFXlMZVsBcvOiOIFUeeUK3AIGNAujZqSk492YvIOSolgpu/HfYZ0cfJAo/ewwLzkDIc6ErjqasTpZ5KwB/DDnr3WNkaDE=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-i/. Click or tap if you trust this link.">Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT.</a><br aria-hidden="true" style="line-height: inherit;" />Jayne, D., et al. (2022). <em style="line-height: inherit;">Health Technology Assessment.</em><br aria-hidden="true" style="line-height: inherit;" /><a data-auth="Verified" data-linkindex="7" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-d%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242905050%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=U0PA%2B7ol1bzQt6pNNLwcforsuh7VPacGddtAHrtLo1U%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-d/" rel="noopener noreferrer" shash="a92E3mJM2mNRaz4fdKPZ6maPQMcHBzEN5mRcy0WJFth6sQz5U7CeQHh0fTHRa/BxjR841tVjPQtIZPs1w7DgGhXu218aLK8NoZDM15VEcCRiGmCS7ozeMPF/FegYRw1d5ZmBNIgUD+FO0dbXgXMorBDaYlp5uZ+hZDkTMHcjakg=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-d/. Click or tap if you trust this link."><strong style="line-height: inherit;"><span style="border: 0px; color: rgb(220, 53, 69) !important; font: inherit; margin: 0px; padding: 0px; text-decoration: inherit; vertical-align: baseline;">PICO SUMMARY</span></strong></a></p></div></div><div style="background-color: white; border: 0px; color: #565656; font-family: sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 14px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; margin: 0px 20px; padding: 0px; vertical-align: baseline;"><div aria-hidden="true" class="x_divider" style="background-color: rgb(200, 200, 200) !important; border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 2px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: 2px; margin: 0px auto 20px; padding: 0px; vertical-align: baseline; width: 40px;"> </div></div><div style="background-color: white; border: 0px; color: #565656; font-family: sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 14px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; margin: 0px 20px; padding: 0px; vertical-align: baseline;"><div style="border: 0px; color: inherit; font: inherit; margin: 0px; padding: 0px; vertical-align: middle;"><p class="x_size-18" lang="x-size-18" style="font-size: 17px; line-height: 26px; margin-bottom: 20px; margin-top: 0px;"><strong style="line-height: inherit;"><span style="border: 0px; color: rgb(220, 53, 69) !important; font: inherit; margin: 0px; padding: 0px; text-decoration: inherit; vertical-align: baseline;">Selected articles</span></strong></p></div></div><div style="background-color: white; border: 0px; color: #565656; font-family: sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 14px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; margin: 0px 20px; padding: 0px; vertical-align: baseline;"><div style="border: 0px; color: inherit; font: inherit; margin: 0px; padding: 0px; vertical-align: middle;"><p style="line-height: inherit; margin-bottom: 0px; margin-top: 0px;"><a data-auth="Verified" data-linkindex="8" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-h%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242912274%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=GHEUKt%2FT8s4TRDo4ISA8Gtk8ZIsrrOcT1jVOwrN3L2o%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-h/" rel="noopener noreferrer" shash="w15gJR2T9d0oQDBnjS6gBt85DAgoU7Z27NNaB+ZJzFmOotkpdS7xJPmPg++58vHl4ZNxuEjO4KWTD1mhpA2GieuN/DHHDoaLMdaOXZ3fyJozurD0pAj/ugSHHQB/WTrktEe+/WONQyaEHZAfN7XhrNQKaR5cai7+5zemwgeIck4=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-h/. Click or tap if you trust this link.">Safety and efficacy of hypoxia-inducible factor-prolyl hydroxylase inhibitors vs. erythropoietin-stimulating agents in treating anemia in renal patients (with or without dialysis): a meta-analysis and systematic review.</a><br aria-hidden="true" style="line-height: inherit;" />Damarlapally, N., et al. (2023). <em style="line-height: inherit;">Cureus.</em></p><p style="line-height: inherit; margin-bottom: 0px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="9" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-k%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242919702%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=8JM%2FHA6ItajsBugYHJdDlRz0m%2BcPbUT%2BDqSF3gXODAw%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-k/" rel="noopener noreferrer" shash="VLv28Q+JHLvj0HlYWgKwmc7OZSMy756YOhrmelgeto9IcF5gTMAlcA9n1et6CaFBQBHffOKsgT6vqhL/jThyTwGP1f01SrUM9Ygy3+uC8jkwZdvk7QKrGHclESZIKyK50bgpLr2lb+W3dWHE6ifffrYjGv3LWfU0CBiTYJ7GsdM=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-k/. Click or tap if you trust this link.">Acute respiratory distress syndrome, acute kidney injury, and mortality after trauma are associated with increased circulation of syndecan-1, soluble thrombomodulin, and receptor for advanced glycation end products.</a><br aria-hidden="true" style="line-height: inherit;" />Dixon, A., et al. (2023). <em style="line-height: inherit;">The Journal of Trauma and Acute Care Surgery.</em></p><p style="line-height: inherit; margin-bottom: 0px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="10" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-u%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242927463%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=UAmEdMRdEtpRbEw9OlzW8hpC25QDfKFF6ToT%2Bn4cm2A%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-u/" rel="noopener noreferrer" shash="cdt2DTnr/sEF8QZU70IDSnF9qFpRTMKSbmHYhBcReVFh6zfVnJqEvgdbU4zUSAK7vGlwxV7Es37acNgYy+6lMhmccRvsByZQTkL+OKzWfyrNDKfxwkCvC2Nf4ni7FJLxwMJ8bO6gximirRrbL1Czwpn+gO6hivrhEIhcgQI1eL4=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-u/. Click or tap if you trust this link.">Can trajectory nor-epinephrine infiltration reduce blood loss during percutaneous nephrolithotomy? A double-blinded randomized controlled trial.</a><br aria-hidden="true" style="line-height: inherit;" />El-Shaer, W., et al. (2022). <em style="line-height: inherit;">International Journal of Urology.</em></p><p style="line-height: inherit; margin-bottom: 0px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="11" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-o%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242935214%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=4V9VKt6hUuuQScezlFQ%2B8JVHgejEcPLdGCqUixOgusM%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-o/" rel="noopener noreferrer" shash="mo5rBmwqJIN1nHMfqPjpMDaupm6nJYo6vz4n0ESxyaS23rifE1F6nf+pL+KnRJzoZhU6istb/fn0psUE9NvyB//pPIQSPnQDkIRxCKAbh3mhcvvQCQpchWq01igbZuPUBdHBpbzb06UxvlSqWlxjcycsJwOLBE6y4wPbHmVBjPs=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-o/. Click or tap if you trust this link.">Prevention of cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis of non-pharmacological interventions.</a><br aria-hidden="true" style="line-height: inherit;" />Hariri, G., et al. (2023). <em style="line-height: inherit;">Critical Care.</em></p><p style="line-height: inherit; margin-bottom: 0px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="12" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-b%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242943204%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=PjLrcK5HJVgHqo4l%2FTNC%2FbGzVdgm1ceV5Dxi54h0wZc%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-b/" rel="noopener noreferrer" shash="BaAaSkg8zJcfvM36LngWuPnb4QKXAJEfTm1qh4k7neVZFxm5cAGQjk1pLWvrQag8srjOetKpos/LYB0zwrNPBe3Lecqbf7ZnJ7+wo3+aQBB0Uvc/Fv5C2JkonUPDj9mgauWyBAfy7PcxQL2MMk0EkgLJFq5osHA556TuFtQp0lU=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-b/. Click or tap if you trust this link.">Effect of blood transfusion post kidney transplantation on de novo human leukocytes antigen donor-specific antibody development and clinical outcomes in kidney transplant recipients: a systematic review and meta-analysis.</a><br aria-hidden="true" style="line-height: inherit;" />Kang, Z.Y., et al. (2023). <em style="line-height: inherit;">Transplant Immunology.</em></p><p style="line-height: inherit; margin-bottom: 0px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="13" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-p%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242950399%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=dA52OwgjbAHWFC5yVRQH6llDX0fLxdGmEyZfKIQ4dG0%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-p/" rel="noopener noreferrer" shash="SNPXojwKyhz7DPNHIu1ku/Mw5Yv2a1Z9wUOf3s5Naef1XVKMpU6O9udP/lzJ/a3o1NWshgyJXJiBS33u/3qsgI56/lB0Dd4zRSZsZfYFI7ky9fn6l3DybqXTHrriyuYToFX/TMOa4I8TiWlG8n5l9Vjs9Tk01I6hCHMgdd4vdVc=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-p/. Click or tap if you trust this link.">Ferric citrate for the treatment of hyperphosphatemia and anemia in patients with chronic kidney disease: a meta-analysis of randomized clinical trials.</a><br aria-hidden="true" style="line-height: inherit;" />Li, L., et al. (2022). <em style="line-height: inherit;">Renal Failure.</em></p><p style="line-height: inherit; margin-bottom: 0px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="14" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-x%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242957504%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=Dc7MUWH97RP6s26vH5ehi%2B6i44o7xDD5vatOULR5Us0%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-x/" rel="noopener noreferrer" shash="CsJ7Ba+YQnzygebiLFgiIH5uzxMma2mhiy3usYGMREJTLJ6Z2JhqJqn/Cq26avz+pt8VWB+Tb/NmMtmO92eZtW4O68aiRmRBQORu0mN2Waqz5mPav69M+dNnXeRQI70aIWLZXTHryUJfeWRuT3wR/6piVGRweGiiGzq8shg3Bt0=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-x/. Click or tap if you trust this link.">The effect of perioperative blood transfusion on survival after renal cell carcinoma nephrectomy: a systematic review and meta-analysis.</a><br aria-hidden="true" style="line-height: inherit;" />Liu, Y., et al. (2023). <em style="line-height: inherit;">Frontiers in Oncology.</em></p><p style="line-height: inherit; margin-bottom: 0px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="15" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-m%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242964733%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=0%2FiOikdmuGjP%2BpX%2Bn%2FVo%2B5Jf6eDxr9WJHsxXORje8YM%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-m/" rel="noopener noreferrer" shash="zBEFwBRlcz4tknD2U+MzFbsusDhOm4524q6wX9as4XtIkuO9aL9SPI+NoXBmjj7yivPMewEbm1MBdOlyTotTUua6joEyDaA1J7Bken5k+CcFzaZyhaztLElSEJoK10y2oJcwcb3PmiVX5VwzVcNh7osmJUZRB+bCYaAFvoZpHio=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-m/. Click or tap if you trust this link.">Efficacy of therapeutic apheresis for cryoglobulinemic vasculitis patients with renal involvement: a systematic review.</a><br aria-hidden="true" style="line-height: inherit;" />Miao, J., et al. (2023). <em style="line-height: inherit;">Blood Purification.</em></p><p style="line-height: inherit; margin-bottom: 20px; margin-top: 20px;"><a data-auth="Verified" data-linkindex="16" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-eydluky-btjdykrlh-c%2F&data=05%7C02%7Cd.styles%40nhs.net%7C2101ab551cee45009eba08dc44070b31%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638460044242976338%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=kjerK3OFvdMrhOTzzOiMypLrZCcEvil5vdF7KxXp7n0%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-c/" rel="noopener noreferrer" shash="LMH6eQcFrUjbsW2ZXcNxxZqxoPpUQkH1NxBm5+YyDV06cQdMkdUoWglqEZgffAlCrF2MNj6yMMBR/gB1FvfBonVqyj1VbxS5lTKwEm7TFUT6tbi6I/7XVuo2GYF71DT0GKZ9GuyTXWfTbYAHxBuvWrl75XwpPHf3Zq3kpJ2tr6E=" style="border: 0px; color: rgb(65, 99, 126) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-eydluky-btjdykrlh-c/. Click or tap if you trust this link.">Two phase 3 studies on ophthalmologic effects of roxadustat versus darbepoetin.</a><br aria-hidden="true" style="line-height: inherit;" />Sepah, Y.J., et al. (2022). <em style="line-height: inherit;">Kidney International Reports.</em></p></div></div>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-80188225986457904532024-03-17T10:18:00.005+00:002024-03-17T10:18:36.342+00:0013 March 2024 (Wednesday) - Hyperthyroidism<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgkC7FHkIVj4o63Z2a9ruSaymy7SpWP1tl1foB9t-g7Sm98SDc2_So1LGYZZDgMVfK3KfkXHK5HEx5IZZidEohhWeqbzkPjYP2ltu-jeu2T-fnMy5XZuP5qXR0Xvo55OWWrzTmXoRmnNQMlnyhHqEJn8H052aCAaFHLXmmvGQn-3Uf6cIUF_FuG_GQ0Zyw/s140/me1.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="139" data-original-width="140" height="318" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgkC7FHkIVj4o63Z2a9ruSaymy7SpWP1tl1foB9t-g7Sm98SDc2_So1LGYZZDgMVfK3KfkXHK5HEx5IZZidEohhWeqbzkPjYP2ltu-jeu2T-fnMy5XZuP5qXR0Xvo55OWWrzTmXoRmnNQMlnyhHqEJn8H052aCAaFHLXmmvGQn-3Uf6cIUF_FuG_GQ0Zyw/w320-h318/me1.jpg" width="320" /></a></div><p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">We had a patient today with a mild
neutropenia. The patient’s diagnosis was hyperthyroidism.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><a href="https://www.thyroid.org/wp-content/uploads/publications/ctfp/volume14/issue2/ct_public_v142_11_12.pdf">It
transpires that</a> treatment of hyperthyroidism often causes a neutropenia
which resolves on cessation of treatment.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">Something to bear in mind.<o:p></o:p></span></p><div style="text-align: justify;"><br /></div><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-21316870985833391312024-03-17T10:12:00.001+00:002024-03-17T10:12:11.569+00:0012 March 2024 (Tuesday) - IBMS Newsletter<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh3H_HU__OGQviDPzhTGWWsM3SZQyixq4-jVSnPRJnDHI-zTGlfArX8hqwECVIQ1F9YQu7LzSruGUyCvYpFiB3zvmRcrSNcvC4bFQBpT80oCZYUHokyjLr0t8VmPGjxIqCyEzRve40bNpUEV6gBNUgY2_Hq8i0ksK7Df5Y2xlwc11X4Sv12l_LnEg6vcwQ/s281/ibms.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="229" data-original-width="281" height="229" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh3H_HU__OGQviDPzhTGWWsM3SZQyixq4-jVSnPRJnDHI-zTGlfArX8hqwECVIQ1F9YQu7LzSruGUyCvYpFiB3zvmRcrSNcvC4bFQBpT80oCZYUHokyjLr0t8VmPGjxIqCyEzRve40bNpUEV6gBNUgY2_Hq8i0ksK7Df5Y2xlwc11X4Sv12l_LnEg6vcwQ/s1600/ibms.jpg" width="281" /></a></div><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif;">The IBMS Newsletter appeared in my
in-box this morning. You can read it </span><a href="https://mailchi.mp/ibms.org/ibms-monthly-newsletter-1674403?e=824a6c66b2" style="font-family: Arial, sans-serif;">by
clicking here</a><span style="font-family: Arial, sans-serif;">.</span></div><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">It is widely said that in this life <a href="https://dictionary.cambridge.org/dictionary/english/come-go-turn-full-circle">things
go full-circle</a>. I suspect that in thirty years’ time a future issue of the
IBMS gazette will feature articles on the latest advances on blood testing
analysers and reagent kits, and tutorials on cell morphology and
interpretations of haemoglobinopathy traces. And the olduns of that era (<i>today’s
trainees</i>) will hark back to the halcyon days of 2024 when the IBMS focused on
what mattered to them; committees and awards and strange catchphrases.</div></span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-10859967988846513442024-03-17T10:03:00.002+00:002024-03-17T10:03:38.540+00:0012 March 2024 (Tuesday) - Oncology Central<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjW1Nm-l13NR6suNLHlMZjqsRIX3gcTE3Q9_8G96Z2OayrWpnXP-4C8eo02HBZIr2OCQf4QjFInB5vXXkKLvZYHnmFlohrZ-Lx9FQgg_qjPb2Aawx16PzynNxegdzQSbYYUdscREqye2sCS-0T6MrbR23b2oh7ASmVkFZcHI4NQRT8XhftVBQl4yD77Sp0/s531/oncology%20central.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="71" data-original-width="531" height="86" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjW1Nm-l13NR6suNLHlMZjqsRIX3gcTE3Q9_8G96Z2OayrWpnXP-4C8eo02HBZIr2OCQf4QjFInB5vXXkKLvZYHnmFlohrZ-Lx9FQgg_qjPb2Aawx16PzynNxegdzQSbYYUdscREqye2sCS-0T6MrbR23b2oh7ASmVkFZcHI4NQRT8XhftVBQl4yD77Sp0/w640-h86/oncology%20central.jpg" width="640" /></a></div><p></p><p class="MsoNormal"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">The nice people at Oncology Central sent
their update today. Much (<i>most</i>) of it went over my head, but one or two
things stuck<o:p></o:p></span></p><div class="x_hse-section" id="x_module_1707386692814" style="background-color: #eaf0f6; border: 0px; font-family: Helvetica, Arial, sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 15px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; margin: 0px; padding: 0px 10px; vertical-align: baseline;"><div bgcolor="#ffffff" class="x_hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; border: 0px; color: inherit; font: inherit; margin: 0px auto; max-width: 600px; min-width: 280px; padding: 10px 0px; vertical-align: baseline; width: 600px !important;"><div class="x_hse-column x_hse-size-6" id="x_module_1707386692814_0" style="border: 0px; color: inherit; display: table-cell; font: inherit; margin: 0px; max-width: 300px !important; padding: 0px; vertical-align: top; width: 300px !important;"><div class="x_hs_cos_wrapper x_hs_cos_wrapper_widget x_hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="x_hs_cos_wrapper_module_17073866927691" style="border: 0px; color: inherit; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"><table cellpadding="0" cellspacing="0" class="x_hse-image-wrapper" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; font: inherit; width: 100%;"><tbody><tr><td align="center" class="x_hs_padded" style="border-collapse: collapse; font-size: 0px; padding: 0px 20px; text-align: center; word-break: break-word;" valign="top"><a data-auth="Verified" data-hs-link-id="0" data-linkindex="5" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Finfo.future-science-group.com%2Fe3t%2FCtc%2F5D%2B113%2FcQP5s04%2FVV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3H5nR32W50kH_H6lZ3njW6w7QCM34wttyW79grky7llMZQW61Qgp-3cR7ptVL98-H3Kzj0XW5M0B0L10vbK5MTQKPYlnSVmN8MPD5G9G9z5VDHthq50r-jzW6cMrlC21rc-xVMHHFm3fjZQhW73ttFx2hrqKvMPSVx8lSCYpW42FxcT7s7jVcW4Rv6Wy2YXTTXW8gxqld3lJXYLW39Hk956M9gymW8Dmgrt8rj-qXW9cQFNl1H9jZVW5ykbjw184YX7W5z8b2r3QSK9HW1_8NSX2f3hx-W5gWVDY1lQ-2dW81kfCj8xz1TCW7VQGQ97vvn4rN23zRzbbjRHYW7vNx6q5x2HvRW3y1HxT7pqp2bW1tsx567NYf67W5hrXLH8JN9MzN7HzvpC-M3MzW3jBY341TN762W6K_pJX9jvKtJd7k2sC04&data=05%7C02%7Cd.styles%40nhs.net%7Ca55142915d714bea901e08dc3f6b1cd9%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638454976493000835%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=YDFXDDyKBOnhaMaqbuOriKSIgNy5%2FBAQYXqTbVU%2BLxQ%3D&reserved=0" originalsrc="https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3H5nR32W50kH_H6lZ3njW6w7QCM34wttyW79grky7llMZQW61Qgp-3cR7ptVL98-H3Kzj0XW5M0B0L10vbK5MTQKPYlnSVmN8MPD5G9G9z5VDHthq50r-jzW6cMrlC21rc-xVMHHFm3fjZQhW73ttFx2hrqKvMPSVx8lSCYpW42FxcT7s7jVcW4Rv6Wy2YXTTXW8gxqld3lJXYLW39Hk956M9gymW8Dmgrt8rj-qXW9cQFNl1H9jZVW5ykbjw184YX7W5z8b2r3QSK9HW1_8NSX2f3hx-W5gWVDY1lQ-2dW81kfCj8xz1TCW7VQGQ97vvn4rN23zRzbbjRHYW7vNx6q5x2HvRW3y1HxT7pqp2bW1tsx567NYf67W5hrXLH8JN9MzN7HzvpC-M3MzW3jBY341TN762W6K_pJX9jvKtJd7k2sC04" rel="noopener noreferrer" shash="wFF6XNVDUh2TQGV7hBMAwXOYupIsnNVkTu67LwhngfyYC1HCjJKxNfPL3x28rCPtYxUbrEGg/s16g54YAtDif9Ae0sJDksXdTm7cFvNAqKqcLDrvhNqCGvzd3xbGb9BFfSkKNDo3MT52G1O0yEiJ/DWX7lbI3GTtIkw9PGI+Pao=" style="border: 0px; color: #00a4bd; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3H5nR32W50kH_H6lZ3njW6w7QCM34wttyW79grky7llMZQW61Qgp-3cR7ptVL98-H3Kzj0XW5M0B0L10vbK5MTQKPYlnSVmN8MPD5G9G9z5VDHthq50r-jzW6cMrlC21rc-xVMHHFm3fjZQhW73ttFx2hrqKvMPSVx8lSCYpW42FxcT7s7jVcW4Rv6Wy2YXTTXW8gxqld3lJXYLW39Hk956M9gymW8Dmgrt8rj-qXW9cQFNl1H9jZVW5ykbjw184YX7W5z8b2r3QSK9HW1_8NSX2f3hx-W5gWVDY1lQ-2dW81kfCj8xz1TCW7VQGQ97vvn4rN23zRzbbjRHYW7vNx6q5x2HvRW3y1HxT7pqp2bW1tsx567NYf67W5hrXLH8JN9MzN7HzvpC-M3MzW3jBY341TN762W6K_pJX9jvKtJd7k2sC04. 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Click or tap if you trust this link.">Championing diversity and inclusion in neuro-oncology</a></span></h1><p style="line-height: 30px; margin: 0px;"><a data-auth="Verified" data-hs-link-id="2" data-linkindex="7" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Finfo.future-science-group.com%2Fe3t%2FCtc%2F5D%2B113%2FcQP5s04%2FVV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3H5nR32W50kH_H6lZ3ndW2ppxQQ8SRwG1W2r_P-55kmJ8ZW8lPM5d5J0f53W4k6Z1l1y6VtDN6-D26rrMYcHVjQn3y8Qz7b-W4x0FHt94cLwQW1BYjf-4sZwNHW3-DF_F5w9wNdW2cRp3q5vhsG1W7c6JH37spM0kN5wSJKC2dKVNN6wn7G95Y-_nW7LN8SS46cm_cW78Tkm52f8gMcN5gHlJVng4N0W7BmB5H6RBrl8W1F_sQ32w-6QSW5whTWH4xzS6bVp_k0m5RT7McW3KV3624jq388W6n0n3M2RQ7QxW6YphRc7SFwz9W4GJHCD6jJkbfW67F1w96B_50jVzC5S22sP3YlW6jFcsD8WD6b3W92Ps023XhFSnW93gRxx3c1BVWW6B6YWN5HP-QSW1y4N4k2Bp42-W5Vs8ZK6V8_WVf5T-Djx04&data=05%7C02%7Cd.styles%40nhs.net%7Ca55142915d714bea901e08dc3f6b1cd9%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638454976493020802%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=7nJvBSrQXNYM8n6MulSbKIr2gTkCf6NVvDjfuvnMn%2Fs%3D&reserved=0" originalsrc="https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3H5nR32W50kH_H6lZ3ndW2ppxQQ8SRwG1W2r_P-55kmJ8ZW8lPM5d5J0f53W4k6Z1l1y6VtDN6-D26rrMYcHVjQn3y8Qz7b-W4x0FHt94cLwQW1BYjf-4sZwNHW3-DF_F5w9wNdW2cRp3q5vhsG1W7c6JH37spM0kN5wSJKC2dKVNN6wn7G95Y-_nW7LN8SS46cm_cW78Tkm52f8gMcN5gHlJVng4N0W7BmB5H6RBrl8W1F_sQ32w-6QSW5whTWH4xzS6bVp_k0m5RT7McW3KV3624jq388W6n0n3M2RQ7QxW6YphRc7SFwz9W4GJHCD6jJkbfW67F1w96B_50jVzC5S22sP3YlW6jFcsD8WD6b3W92Ps023XhFSnW93gRxx3c1BVWW6B6YWN5HP-QSW1y4N4k2Bp42-W5Vs8ZK6V8_WVf5T-Djx04" rel="noopener noreferrer" shash="QBGnlUGhDySB6mQ0LOwq8gPR3/hhAEs5ZvZZypJD158fOgnVnsT1wcnmJ7fhpfi76gHg8CvBXTxe5DVT8NT6hQ1/28AAsPFQmp9lS4LedFltnYhn7qKbrTnpQbLJfWJKQj/r0YX7vWmk2yjV7yCWKl83pl2KzINQ4FObb7TWKRs=" style="border: 0px; color: #00a4bd; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3H5nR32W50kH_H6lZ3ndW2ppxQQ8SRwG1W2r_P-55kmJ8ZW8lPM5d5J0f53W4k6Z1l1y6VtDN6-D26rrMYcHVjQn3y8Qz7b-W4x0FHt94cLwQW1BYjf-4sZwNHW3-DF_F5w9wNdW2cRp3q5vhsG1W7c6JH37spM0kN5wSJKC2dKVNN6wn7G95Y-_nW7LN8SS46cm_cW78Tkm52f8gMcN5gHlJVng4N0W7BmB5H6RBrl8W1F_sQ32w-6QSW5whTWH4xzS6bVp_k0m5RT7McW3KV3624jq388W6n0n3M2RQ7QxW6YphRc7SFwz9W4GJHCD6jJkbfW67F1w96B_50jVzC5S22sP3YlW6jFcsD8WD6b3W92Ps023XhFSnW93gRxx3c1BVWW6B6YWN5HP-QSW1y4N4k2Bp42-W5Vs8ZK6V8_WVf5T-Djx04. 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Click or tap if you trust this link.">How can AI help provide real-time insights into glioblastoma?</a></p><p style="line-height: 30px; margin: 0px;"><a data-auth="Verified" data-hs-link-id="2" data-linkindex="11" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Finfo.future-science-group.com%2Fe3t%2FCtc%2F5D%2B113%2FcQP5s04%2FVV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd4g5nR32W69t95C6lZ3mGN7TGFwBSZP4ZW301pLB2Kdx_0VmTSCY5hyqC3N43MR4NgW11TW4d5Mb62t25xnW5ljdsd3Yk3TfW19dJkl503qPKW8Br4Gz41kPfhW71rlX812lRY8W7GmYGF5gfTvyW4YD-l17z_ZLrN925fTq61BnBW2dMsSQ3xRbTGW843H-B7LsgMvW5Z8lgP6_9BFdW8qpSzD76pJd1W2hV4yZ29MGYlVTW8LY7ZJJ42W6wNTlg7nRLY7W6J9HLC7qXCdWW3L0DwL1TgG-GVmdDvv8jH-8gW8JQsT-4L1yB7W8C-w_N92yjBvN44C6VCQq489N5BdthlmXnpYW3pxcq86jqQjrVcnvKZ66f0R6W6zxY131Lj1zwW7Kqd7r4jG-W7W3gXVTB3kfMR5W3MqTG07hWgsDW76fhX89f3QflW5w71Ml3nyttTW2rpFfj5PSmBmW6L-F0K1kfcq7f6r-8WW04&data=05%7C02%7Cd.styles%40nhs.net%7Ca55142915d714bea901e08dc3f6b1cd9%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638454976493060482%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=P9t6fYycZxR4mcCct8Z660lqbcHCc30aII5LKZcRlUs%3D&reserved=0" originalsrc="https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd4g5nR32W69t95C6lZ3mGN7TGFwBSZP4ZW301pLB2Kdx_0VmTSCY5hyqC3N43MR4NgW11TW4d5Mb62t25xnW5ljdsd3Yk3TfW19dJkl503qPKW8Br4Gz41kPfhW71rlX812lRY8W7GmYGF5gfTvyW4YD-l17z_ZLrN925fTq61BnBW2dMsSQ3xRbTGW843H-B7LsgMvW5Z8lgP6_9BFdW8qpSzD76pJd1W2hV4yZ29MGYlVTW8LY7ZJJ42W6wNTlg7nRLY7W6J9HLC7qXCdWW3L0DwL1TgG-GVmdDvv8jH-8gW8JQsT-4L1yB7W8C-w_N92yjBvN44C6VCQq489N5BdthlmXnpYW3pxcq86jqQjrVcnvKZ66f0R6W6zxY131Lj1zwW7Kqd7r4jG-W7W3gXVTB3kfMR5W3MqTG07hWgsDW76fhX89f3QflW5w71Ml3nyttTW2rpFfj5PSmBmW6L-F0K1kfcq7f6r-8WW04" rel="noopener noreferrer" shash="x2eWQL9Ry7w6qhoYqQZz2VtYd6RZlCclokVhW5nAYiqglosW0rjN5Dral7jZjfQ67y1ZTl9TE7wsFGTC3bjT4CQRduO8g+NLtYgX00994L4lgijjzySMdfXF8yZZzO1rysvFOo5bJg2vIx1R8/c08gvT2AI2iG8RiEsfR/IShrE=" style="border: 0px; color: #00a4bd; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd4g5nR32W69t95C6lZ3mGN7TGFwBSZP4ZW301pLB2Kdx_0VmTSCY5hyqC3N43MR4NgW11TW4d5Mb62t25xnW5ljdsd3Yk3TfW19dJkl503qPKW8Br4Gz41kPfhW71rlX812lRY8W7GmYGF5gfTvyW4YD-l17z_ZLrN925fTq61BnBW2dMsSQ3xRbTGW843H-B7LsgMvW5Z8lgP6_9BFdW8qpSzD76pJd1W2hV4yZ29MGYlVTW8LY7ZJJ42W6wNTlg7nRLY7W6J9HLC7qXCdWW3L0DwL1TgG-GVmdDvv8jH-8gW8JQsT-4L1yB7W8C-w_N92yjBvN44C6VCQq489N5BdthlmXnpYW3pxcq86jqQjrVcnvKZ66f0R6W6zxY131Lj1zwW7Kqd7r4jG-W7W3gXVTB3kfMR5W3MqTG07hWgsDW76fhX89f3QflW5w71Ml3nyttTW2rpFfj5PSmBmW6L-F0K1kfcq7f6r-8WW04. 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Click or tap if you trust this link.">Navigating opportunities in pancreatic cancer</a></p><p style="line-height: 30px; margin: 0px;"><a data-auth="Verified" data-hs-link-id="2" data-linkindex="14" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Finfo.future-science-group.com%2Fe3t%2FCtc%2F5D%2B113%2FcQP5s04%2FVV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd4z5nR32W6N1X8z6lZ3kyW7sxS9p1K6MMCN3-FztCP2R81W29cY3f8V9rpHW7k2yXn2qlm7ZW4PCqWx3QkCB3W4Zccj06yXddCW5m4zTT6fLrsNN6Kbp7Hgq6YHW6PlnNH7CLq8ZW8t5Rlp8S_PM_W8C74LP4l23BSW5B_47H2d7yx0W3FJY1D83v6nmW2V6QH15yWG-lW6dpW7r1Vc8XfW1JHw7f932mV-N894t7zcrnQsN1bScQHh6z85W2dZTx03M0GspW9b6Bcg3V6qPWW4_-KsM3x83x0W4D24_S5HLpqjW36H4sS90NbwFW5x4YQw2qsGmPN2-rr55qXHKkW1LRtmQ4lQHZ7W52gh6H94XltGVS88JF7TXWMGW45M8pr2Nv6Q1W7wrr5D31YssgW8sHVKN2Dsmw6W2_jwjH7F6bWxW2BDvRY9cmDPMW8w8lKD2P3x73W2cb8jR2VKfNvW2s9T657cZVVHW5Hf_tC7ysfxnW2SQ84p4vLWp2f4J-4Nv04&data=05%7C02%7Cd.styles%40nhs.net%7Ca55142915d714bea901e08dc3f6b1cd9%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638454976493091598%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=l748Jze0BgqQhy%2BVdyjLdGzJR70kMwdASDd7kbvQz%2F4%3D&reserved=0" originalsrc="https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd4z5nR32W6N1X8z6lZ3kyW7sxS9p1K6MMCN3-FztCP2R81W29cY3f8V9rpHW7k2yXn2qlm7ZW4PCqWx3QkCB3W4Zccj06yXddCW5m4zTT6fLrsNN6Kbp7Hgq6YHW6PlnNH7CLq8ZW8t5Rlp8S_PM_W8C74LP4l23BSW5B_47H2d7yx0W3FJY1D83v6nmW2V6QH15yWG-lW6dpW7r1Vc8XfW1JHw7f932mV-N894t7zcrnQsN1bScQHh6z85W2dZTx03M0GspW9b6Bcg3V6qPWW4_-KsM3x83x0W4D24_S5HLpqjW36H4sS90NbwFW5x4YQw2qsGmPN2-rr55qXHKkW1LRtmQ4lQHZ7W52gh6H94XltGVS88JF7TXWMGW45M8pr2Nv6Q1W7wrr5D31YssgW8sHVKN2Dsmw6W2_jwjH7F6bWxW2BDvRY9cmDPMW8w8lKD2P3x73W2cb8jR2VKfNvW2s9T657cZVVHW5Hf_tC7ysfxnW2SQ84p4vLWp2f4J-4Nv04" rel="noopener noreferrer" shash="Ta9jzEoCCsM0XvGO471yCVBQTAQMtb8TwKd45hbegDhzyi61OHvPNmn0Idv/FpaQuRSIRqLmdWjXQfIN5I9cMg+400l8UUleBP0nV1cHYHlljYRBrgPv7PlTr9akphkfAqhHZ6GYZyVT+wpRp0RjXa7OIHAgTxzYBPRuasmcbJ4=" style="border: 0px; color: #00a4bd; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd4z5nR32W6N1X8z6lZ3kyW7sxS9p1K6MMCN3-FztCP2R81W29cY3f8V9rpHW7k2yXn2qlm7ZW4PCqWx3QkCB3W4Zccj06yXddCW5m4zTT6fLrsNN6Kbp7Hgq6YHW6PlnNH7CLq8ZW8t5Rlp8S_PM_W8C74LP4l23BSW5B_47H2d7yx0W3FJY1D83v6nmW2V6QH15yWG-lW6dpW7r1Vc8XfW1JHw7f932mV-N894t7zcrnQsN1bScQHh6z85W2dZTx03M0GspW9b6Bcg3V6qPWW4_-KsM3x83x0W4D24_S5HLpqjW36H4sS90NbwFW5x4YQw2qsGmPN2-rr55qXHKkW1LRtmQ4lQHZ7W52gh6H94XltGVS88JF7TXWMGW45M8pr2Nv6Q1W7wrr5D31YssgW8sHVKN2Dsmw6W2_jwjH7F6bWxW2BDvRY9cmDPMW8w8lKD2P3x73W2cb8jR2VKfNvW2s9T657cZVVHW5Hf_tC7ysfxnW2SQ84p4vLWp2f4J-4Nv04. Click or tap if you trust this link."><span style="border: 0px; color: #e37d22; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">READ MORE >>></span></a></p><p aria-hidden="true" style="font-size: 14px; line-height: 17.5px; margin: 0px;"> </p></div></div></td></tr></tbody></table></div></div></div><p class="MsoNormal"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"></span></p><div class="x_hse-section" id="x_module_1709899735843" style="background-color: #eaf0f6; border: 0px; font-family: Helvetica, Arial, sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 15px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; margin: 0px; padding: 0px 10px; vertical-align: baseline;"><div bgcolor="#ffffff" class="x_hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; border: 0px; color: inherit; font: inherit; margin: 0px auto; max-width: 600px; min-width: 280px; padding: 10px 0px; vertical-align: baseline; width: 600px !important;"><div class="x_hse-column x_hse-size-6" id="x_module_1709899735843_0" style="border: 0px; color: inherit; display: table-cell; font: inherit; margin: 0px; max-width: 300px !important; padding: 0px; vertical-align: top; width: 300px !important;"><div class="x_hs_cos_wrapper x_hs_cos_wrapper_widget x_hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="x_hs_cos_wrapper_module_17098997357943" style="border: 0px; color: inherit; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;"><table cellpadding="0" cellspacing="0" class="x_hse-image-wrapper" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; font: inherit; width: 100%;"><tbody><tr><td align="center" class="x_hs_padded" style="border-collapse: collapse; font-size: 0px; padding: 0px 20px; text-align: center; word-break: break-word;" valign="top"><a data-auth="Verified" data-hs-link-id="0" data-linkindex="15" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Finfo.future-science-group.com%2Fe3t%2FCtc%2F5D%2B113%2FcQP5s04%2FVV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3-5nR32W5BWr2F6lZ3nlN7pbWYr4k5V3VrVxdS6V0LtzW6VCdsv6bXj5mW1gX1M1921jvSW77pHCw1rPCCZW7wcc3G5flvHZVZ7zGp924QvRW124c5b7VHdYbN4xwcxnFFGDNVKktCs8C2zyLW8NBrkW8zpNhBN2f6g056wm3JW8CF8hf8mtF9VW5hY5LV7LGMndW1GqtSZ6GGV6pW1LHGDJ498YXGW24Y1tc3snKg2W40dRhX98vTP-W6h34n74NtJSxW9dYLWh3bSb7xW2gM3Wk6nJc8yW9b72sd1Gn9TtW6mNjvy7_qhXkW81cmL-2MhHf0VTVP6m8wHMLJW6qgjvW8FMD0nW7v4rvM7HDRTnW998ShP4JcHsPW6H41gg5VkPf2W6x5SgF9dd-KkW86JfhF7ZRH09W9kQdxn7NdLYmW2qD7sh91WrlZW44QCxy6sRDTcf6VrF6x04&data=05%7C02%7Cd.styles%40nhs.net%7Ca55142915d714bea901e08dc3f6b1cd9%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638454976493102447%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=V5X4%2FSRVKrnQwMakO4Mx86thwQoi1YUZwjQ1X3Hryr4%3D&reserved=0" originalsrc="https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3-5nR32W5BWr2F6lZ3nlN7pbWYr4k5V3VrVxdS6V0LtzW6VCdsv6bXj5mW1gX1M1921jvSW77pHCw1rPCCZW7wcc3G5flvHZVZ7zGp924QvRW124c5b7VHdYbN4xwcxnFFGDNVKktCs8C2zyLW8NBrkW8zpNhBN2f6g056wm3JW8CF8hf8mtF9VW5hY5LV7LGMndW1GqtSZ6GGV6pW1LHGDJ498YXGW24Y1tc3snKg2W40dRhX98vTP-W6h34n74NtJSxW9dYLWh3bSb7xW2gM3Wk6nJc8yW9b72sd1Gn9TtW6mNjvy7_qhXkW81cmL-2MhHf0VTVP6m8wHMLJW6qgjvW8FMD0nW7v4rvM7HDRTnW998ShP4JcHsPW6H41gg5VkPf2W6x5SgF9dd-KkW86JfhF7ZRH09W9kQdxn7NdLYmW2qD7sh91WrlZW44QCxy6sRDTcf6VrF6x04" rel="noopener noreferrer" shash="Hp9icSiDW78ir6v/d1P3u3yicgQaasPp8aHZJGDU8GmFbBvw0fezx290MxNoB1OrmVQDkzbcVlrRWMXFode8dBL62n3dYj62uq47q1d8VBmmxzrvYKBj90Zgms4EiH7IsaukwYx7d156wcrxtg5oF0tCdTGkMZQVDNAfI1YDo/g=" style="border: 0px; color: #00a4bd; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3-5nR32W5BWr2F6lZ3nlN7pbWYr4k5V3VrVxdS6V0LtzW6VCdsv6bXj5mW1gX1M1921jvSW77pHCw1rPCCZW7wcc3G5flvHZVZ7zGp924QvRW124c5b7VHdYbN4xwcxnFFGDNVKktCs8C2zyLW8NBrkW8zpNhBN2f6g056wm3JW8CF8hf8mtF9VW5hY5LV7LGMndW1GqtSZ6GGV6pW1LHGDJ498YXGW24Y1tc3snKg2W40dRhX98vTP-W6h34n74NtJSxW9dYLWh3bSb7xW2gM3Wk6nJc8yW9b72sd1Gn9TtW6mNjvy7_qhXkW81cmL-2MhHf0VTVP6m8wHMLJW6qgjvW8FMD0nW7v4rvM7HDRTnW998ShP4JcHsPW6H41gg5VkPf2W6x5SgF9dd-KkW86JfhF7ZRH09W9kQdxn7NdLYmW2qD7sh91WrlZW44QCxy6sRDTcf6VrF6x04. 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Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: Helvetica, Arial, sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Frontiers in brain tumor research and empowering women in STEM</span></a></h1><p style="line-height: 30px; margin: 0px;"><a data-auth="Verified" data-hs-link-id="2" data-linkindex="17" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Finfo.future-science-group.com%2Fe3t%2FCtc%2F5D%2B113%2FcQP5s04%2FVV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3-5nR32W5BWr2F6lZ3mKW330VCn2DkdWhW5R8Grc6hSFxSW16CVGd5rW9rXW954WlS5kx606W7Wkndn4qmtTPW1zK_668K3qDcW454lC38cH2sZW8NQ1VD23Yzs0W9gvPKw3GgkTpTM7ZV4HkZ0bW94V1xM5d_lQcW4Nqf134qV6QPW2k4fQ39kCpqKW4TwCQ945rMnVW4_q1wW8PSqqKW1DzJ5v8JVXCGW5X5Dln3wknkwW4mXmtd7Yn5LbW7jS-Cf3MXCGLW8nSRqK5_7H3JW7_xVYy9hWxQTW5bBlPb1nGTmlW6b3fpx1wGTccW4M7M4g9ls3SMN82q3hL3PlY4VRnrVK3LtbPzVkz5yD3SqM1pW22KmMR7gpt2fVMPnkG1s0pspS76H2jsww0W7tlMrz4rDmFYW8nG0gp6qcNsDW2QxGmd129NflMqsP0pNQrdrf30S9y604&data=05%7C02%7Cd.styles%40nhs.net%7Ca55142915d714bea901e08dc3f6b1cd9%7C37c354b285b047f5b22207b48d774ee3%7C0%7C0%7C638454976493123688%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=p3M9xZ5WfFb%2BSxZBu86eYaNABbzuxnyHvliyiZZoR%2BE%3D&reserved=0" originalsrc="https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3-5nR32W5BWr2F6lZ3mKW330VCn2DkdWhW5R8Grc6hSFxSW16CVGd5rW9rXW954WlS5kx606W7Wkndn4qmtTPW1zK_668K3qDcW454lC38cH2sZW8NQ1VD23Yzs0W9gvPKw3GgkTpTM7ZV4HkZ0bW94V1xM5d_lQcW4Nqf134qV6QPW2k4fQ39kCpqKW4TwCQ945rMnVW4_q1wW8PSqqKW1DzJ5v8JVXCGW5X5Dln3wknkwW4mXmtd7Yn5LbW7jS-Cf3MXCGLW8nSRqK5_7H3JW7_xVYy9hWxQTW5bBlPb1nGTmlW6b3fpx1wGTccW4M7M4g9ls3SMN82q3hL3PlY4VRnrVK3LtbPzVkz5yD3SqM1pW22KmMR7gpt2fVMPnkG1s0pspS76H2jsww0W7tlMrz4rDmFYW8nG0gp6qcNsDW2QxGmd129NflMqsP0pNQrdrf30S9y604" rel="noopener noreferrer" shash="swgnV8ReF8bYskMCwZtHipJKgREGoEQ4X4qcNCFx1yRio2eDYrloiTqDErN9mK3MgW1Rx19ddyO3gG40DZZBMipqozGnYCaj3CgFYpyOfVsK0SRnsf5DAuvdmk1QOI78Z+B9LElwa9LNllQlR4ILEXAfBP2sVkQMagkB+VOC6QI=" style="border: 0px; color: #00a4bd; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;" target="_blank" title="Original URL: https://info.future-science-group.com/e3t/Ctc/5D+113/cQP5s04/VV-gPl1W1brmW1W41qb3-71bCW2z6fd_5bq4gdN2_Qd3-5nR32W5BWr2F6lZ3mKW330VCn2DkdWhW5R8Grc6hSFxSW16CVGd5rW9rXW954WlS5kx606W7Wkndn4qmtTPW1zK_668K3qDcW454lC38cH2sZW8NQ1VD23Yzs0W9gvPKw3GgkTpTM7ZV4HkZ0bW94V1xM5d_lQcW4Nqf134qV6QPW2k4fQ39kCpqKW4TwCQ945rMnVW4_q1wW8PSqqKW1DzJ5v8JVXCGW5X5Dln3wknkwW4mXmtd7Yn5LbW7jS-Cf3MXCGLW8nSRqK5_7H3JW7_xVYy9hWxQTW5bBlPb1nGTmlW6b3fpx1wGTccW4M7M4g9ls3SMN82q3hL3PlY4VRnrVK3LtbPzVkz5yD3SqM1pW22KmMR7gpt2fVMPnkG1s0pspS76H2jsww0W7tlMrz4rDmFYW8nG0gp6qcNsDW2QxGmd129NflMqsP0pNQrdrf30S9y604. Click or tap if you trust this link."><span style="border: 0px; color: #e37d22; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">READ MORE >>></span></a></p></div></div></td></tr></tbody></table></div></div></div><p> </p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-63759365710176563002024-03-10T19:03:00.003+00:002024-03-10T19:03:18.530+00:0010 March 2024 (Sunday) - BTLP-TACT Exercise<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEheRIviW8HY4cQAIBlVEbWUROVXfNoBpTjZ_LNRLVGnzTUFU03aK7-bhi7k4UtJ7H8hTq1bpGsLmzPia77YhGtpuVxm16_ngDIHXl80My-IHvYp-5n5yVo0Wt7bPLsTvryTYgx3b7HD7bJU7dVrHowhfU1l659rO_JlDWi52VL-Nc1gvx4No9fgQFJeN7g/s700/btlptact.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="248" data-original-width="700" height="141" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEheRIviW8HY4cQAIBlVEbWUROVXfNoBpTjZ_LNRLVGnzTUFU03aK7-bhi7k4UtJ7H8hTq1bpGsLmzPia77YhGtpuVxm16_ngDIHXl80My-IHvYp-5n5yVo0Wt7bPLsTvryTYgx3b7HD7bJU7dVrHowhfU1l659rO_JlDWi52VL-Nc1gvx4No9fgQFJeN7g/w400-h141/btlptact.jpg" width="400" /></a></div><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif;">Time for another BTLP-TACT exercise. I
had one case – a thirty-four year-old woman in the out patients department needing
group & save for “</span><i style="font-family: Arial, sans-serif;">maternal alloantibody</i><span style="font-family: Arial, sans-serif;">”.</span></div><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">She grouped as O Rh(D) Negative with a
negative antibody screen.</div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><i><div style="text-align: justify;"><i><span lang="EN-US" style="font-family: Arial, sans-serif;">“maternal alloantibody</span></i><span lang="EN-US" style="font-family: Arial, sans-serif;">” negative
(!)</span></div></i><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I got the green light</div><span style="font-size: 12pt;"><o:p></o:p></span></span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-66146691731747240022024-03-10T18:52:00.002+00:002024-03-10T18:52:21.393+00:008 MArch 2024 (Friday) - NEQAS 2401 DM<p style="text-align: left;"></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhL6L7yr5GWpA_mt2hyCtwIlx8m84XO2CKGcUNSWzEv63o88_fUkmE_B2670ejpRw6cH2-DyZrmVCnyEL2oPVbRGtdtwGI7FLm9AVmo0jYKbXfiA6dtgPgUL7zmrWhgP5hPzQLm54Bi8IX8boA8aAyo9O6Y-kd_mfSyIuvIx2AtgrtocXmeLDWB9LDezA8/s165/digital%20morphology.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="89" data-original-width="165" height="216" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhL6L7yr5GWpA_mt2hyCtwIlx8m84XO2CKGcUNSWzEv63o88_fUkmE_B2670ejpRw6cH2-DyZrmVCnyEL2oPVbRGtdtwGI7FLm9AVmo0jYKbXfiA6dtgPgUL7zmrWhgP5hPzQLm54Bi8IX8boA8aAyo9O6Y-kd_mfSyIuvIx2AtgrtocXmeLDWB9LDezA8/w400-h216/digital%20morphology.jpg" width="400" /></a></div><div style="text-align: left;"><span style="border: none windowtext 1.0pt; color: black; font-family: "Arial",sans-serif; font-size: 10.0pt; mso-ansi-language: EN-GB; mso-border-alt: none windowtext 0cm; mso-fareast-font-family: "Times New Roman"; mso-fareast-language: EN-GB; padding: 0cm;"><br /></span></div><div style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">“<i>This image
is taken from a blood film of a man aged 61 years. A blood count sent by the GP
showed that the white cell count was 40 x 10^9/L, Hb of 79 g/L and platelets of
118 x 10^9/L. What are your findings?</i>” <br /></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><o:p> <br /></o:p></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><o:p> </o:p></span><table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" style="border-collapse: collapse; border: none; mso-border-alt: solid windowtext .5pt; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt; mso-yfti-tbllook: 1184;">
<tbody><tr style="mso-yfti-firstrow: yes; mso-yfti-irow: 0; mso-yfti-lastrow: yes;">
<td style="border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 155.8pt;" valign="top" width="208">
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;"> <b><u>Rbc </u></b></span><b><u><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></u></b></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;"> </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Anisopoikilocytosis </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Nucleated red
cells </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Polychromasia </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Spherocytes </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Tear drop
cells </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><o:p> </o:p></span></p>
</td>
<td style="border-left: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 155.85pt;" valign="top" width="208">
<p class="MsoNormal" style="text-align: left;"><b><u><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Wbc </span></u></b><b><u><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></u></b></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;"> </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Auer
rods </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Blast
cells </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Dohle
bodies </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Dysplastic
neutrophils </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Hypersegmented
neutrophils </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Left shifted
neutrophils </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Myelocytes </span></p>
</td>
<td style="border-left: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 155.85pt;" valign="top" width="208">
<p class="MsoNormal" style="text-align: left;"><b><u><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Plts </span></u></b><b><u><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></u></b></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;"> </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Grian
plts </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Grey
plts </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: left;"><span style="border: 1pt none windowtext; color: black; font-family: Arial, sans-serif; padding: 0cm;">Megakaryocyte
fragments </span><span style="color: black; font-family: Arial, sans-serif;"><o:p></o:p></span></p>
<p class="MsoNormal" style="tab-stops: 361.5pt;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><o:p> </o:p></span></p>
</td>
</tr>
</tbody></table><span lang="EN-US" style="font-family: Arial, sans-serif;"><o:p> <br /></o:p></span><span lang="EN-US" style="font-family: Arial, sans-serif;">In the absence of any useful clinical
information I felt this was a case of primary myelofibrosis transforming into
something nasty.<br /></span><span lang="EN-US" style="font-family: Arial, sans-serif;">It was.<br /></span><span lang="EN-US" style="font-family: Arial, sans-serif;">However I feel I must ask myself what I
meant by “<i>Grian plts</i>” Bearing in mind nearly two months passed between
my looking at the film and getting the results I have no recollection.</span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-83082986227386647282024-03-10T18:39:00.006+00:002024-03-10T18:39:32.215+00:008 March 2024 (Friday) - NEQAS Parasitology<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhibgnaEvKzgYogAgOa3ORCRzJkA9P4NDnQgqftYA9xAfeSlaUrIB2ZKx8UGkUIfWO5SIS6MUNp-EQenMJ69Wr3xI3KHmbshg9q3suqAuRi9wOfgv2Rz0mP_bhkBHDBpcgJpcE0tiDsFnEoqCkvtC9IeVApH51VraaNl31J7xLjuO2tNa6mJuIOQulF3AI/s572/me%20microscope.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="400" data-original-width="572" height="224" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhibgnaEvKzgYogAgOa3ORCRzJkA9P4NDnQgqftYA9xAfeSlaUrIB2ZKx8UGkUIfWO5SIS6MUNp-EQenMJ69Wr3xI3KHmbshg9q3suqAuRi9wOfgv2Rz0mP_bhkBHDBpcgJpcE0tiDsFnEoqCkvtC9IeVApH51VraaNl31J7xLjuO2tNa6mJuIOQulF3AI/s320/me%20microscope.jpg" width="320" /></a></div><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif; font-size: 12pt;">2401 PA1</span></div><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;"> </span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;">In my notes I actually wrote “</span><i style="font-size: 12pt;">odd
things… probably parasites</i><span style="font-size: 12pt;">”. They were parasites of P malariae.</span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;"> </span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;">But this was a thick film… I saw what
could have been parasites, but I don’t pretend to be an expert at thick films.</span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;">In reality I would have asked for a
second opinion. It wouldn’t have been missed, and that is the main thing.</span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;"> </span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;"> </span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;">2401 PA2</span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;"> </span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;">I saw parasites of P. falciparum with a
parasitaemia of 4%. The consensus opinion was that the parasitemia was 1.5%. I’m
over-estimating, but better over than under.</span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;"> </span></div></span><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;">I’ll claim that as a success.</span></div></span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-32285649111584843932024-03-07T21:21:00.011+00:002024-03-07T21:21:56.299+00:007 March 2024 (Thursday) - BTLP-TACT Exercise<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgqdgmw8V77VjFFaiPXYHQ3n7EaBf87H6-KOg-sYw3PFLppdKI0NDuJrzBAhzmPP2b5Y62FGajJ-DdkvveJjpz0fiKQEXnxIj3PGKlkLVneeXeU2ZsX2yeZUiL3d-j2eInQyaf1BYABEmefagYPk8IFfYskZbUH0f3y9rN2o7Zag_qCers_NcmwtEQHCJo/s700/btlptact.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="248" data-original-width="700" height="141" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgqdgmw8V77VjFFaiPXYHQ3n7EaBf87H6-KOg-sYw3PFLppdKI0NDuJrzBAhzmPP2b5Y62FGajJ-DdkvveJjpz0fiKQEXnxIj3PGKlkLVneeXeU2ZsX2yeZUiL3d-j2eInQyaf1BYABEmefagYPk8IFfYskZbUH0f3y9rN2o7Zag_qCers_NcmwtEQHCJo/w400-h141/btlptact.jpg" width="400" /></a></div><div style="text-align: left;"><div style="text-align: justify;"><span style="font-size: medium;"><span style="font-family: Arial, sans-serif;">Time for another BTLP-TACT exercise. I
must admit I approached this with a sense of “</span><i style="font-family: Arial, sans-serif;">how will I fail this time?</i><span style="font-family: Arial, sans-serif;">”</span></span></div><span style="font-size: medium;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I had one case – a forty-four yar-old
woman in the out-patients department needing group and save. She grouped as O
Rh(D) Positive with a negative antibody screen.</div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I got the green light.</div></span></span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-30723190419323067282024-03-07T21:11:00.004+00:002024-03-07T21:11:31.808+00:007 March 2024 (Thursday) - Sample Transport<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhkdQf03rLDXduLiyOqZQG8LwuSl906dMeVrF2-jKSqP_1MEMMpnlg0XcpdrUYoQJLlr5va64ZNKsh6eWMgup8D5rpcH0rQdpc-cxNf8CUbpq-oNamkT8xI2r5rQQ43AcTAm4PL6Bbn_-0rvoGGFxwSeC40qGfZmHZilnRKfsh9_tXdMVziszNk7pdQxic/s1000/lablogatory.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="217" data-original-width="1000" height="86" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhkdQf03rLDXduLiyOqZQG8LwuSl906dMeVrF2-jKSqP_1MEMMpnlg0XcpdrUYoQJLlr5va64ZNKsh6eWMgup8D5rpcH0rQdpc-cxNf8CUbpq-oNamkT8xI2r5rQQ43AcTAm4PL6Bbn_-0rvoGGFxwSeC40qGfZmHZilnRKfsh9_tXdMVziszNk7pdQxic/w400-h86/lablogatory.jpg" width="400" /></a></div><p></p><div style="text-align: justify;"><span style="font-size: medium;"><span lang="EN-US" style="font-family: Arial, sans-serif;">Here’s <a href="https://labmedicineblog.com/2024/03/07/beam-me-up-scotty/">another
interesting thought</a> from the nice people at Lablogatory. The results we
produce can only be as good as the samples with which we operate.<br /></span><span lang="EN-US" style="font-family: Arial, sans-serif;">For example… you won’t see *<i>that</i>*
many unexpected massively high platelet counts tomorrow. However in a few
months time you may well do so. And you will have a batch pf them… the samples
that were laying in the sun on the dashboard of the car which drove them to the
lab…<br /></span><span lang="EN-US" style="font-family: Arial, sans-serif;">Packaging of samples is important.</span></span></div><p>
</p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-17396507244794829212024-03-07T21:02:00.005+00:002024-03-07T21:02:53.964+00:004 March 2024 (Monday) - Fritsma Factor Newsletter<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiIlercchjxyd_F90DYDJeAaRGAMs0bOBUCBkGBgxmw1sOXtOeh0x4wo0y6ZsB3X8VXWuVhC8cDEO-bewtITUd7cC_wRwWa_EuBAGmGso8sn9AxAsUwtQzU7qDOyOxG-zaAQ_2OePMF5QUW5cTiUhlqgXz5wv5XV6r3SEUAYvIOjySHOkMbjcr6VDt4MnI/s600/fritsma.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="150" data-original-width="600" height="100" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiIlercchjxyd_F90DYDJeAaRGAMs0bOBUCBkGBgxmw1sOXtOeh0x4wo0y6ZsB3X8VXWuVhC8cDEO-bewtITUd7cC_wRwWa_EuBAGmGso8sn9AxAsUwtQzU7qDOyOxG-zaAQ_2OePMF5QUW5cTiUhlqgXz5wv5XV6r3SEUAYvIOjySHOkMbjcr6VDt4MnI/w400-h100/fritsma.jpg" width="400" /></a></div><p></p><div style="text-align: left;"><div style="text-align: justify;"><span style="font-size: medium;"><span style="font-family: Arial, sans-serif;">The </span><a href="https://mailchi.mp/fritsmafactor/6xcd2q5thj-10690937?e=9d23f80dce" style="font-family: Arial, sans-serif;">Fritsma
Factor newsletter</a><span style="font-family: Arial, sans-serif;"> appeared in my in-box today. As always a very useful
source of information…</span></span></div><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"><span style="font-size: medium;">This month there was quite the focus on
mixing studies. These days that is the closest to specialist haemostatic
testing that I do.</span><span style="font-size: 12pt;"> </span></div></span></div><p>
</p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-58892706356644462692024-03-07T20:55:00.005+00:002024-03-07T20:55:40.243+00:004 March 2024 (Monday) - Cold Agglutinins<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhvgy3RCkqe_RVA1W_IVDP78jiTvEgZbK650k2ZvaNTPPwCchM0CPfeOV37Hk_Wi5XKoTiZHVvU0oK4_f0Ga3A24dS-y4FDBgfFaiE6bRbMIu-eLhIjTFqCAjPX37Xa63uGIp-TxREUNix6uK5uLUDu-95zQgABqV4Oxfntafu_I76XpEna4Xe78a6PSTo/s1000/lablogatory.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="217" data-original-width="1000" height="86" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhvgy3RCkqe_RVA1W_IVDP78jiTvEgZbK650k2ZvaNTPPwCchM0CPfeOV37Hk_Wi5XKoTiZHVvU0oK4_f0Ga3A24dS-y4FDBgfFaiE6bRbMIu-eLhIjTFqCAjPX37Xa63uGIp-TxREUNix6uK5uLUDu-95zQgABqV4Oxfntafu_I76XpEna4Xe78a6PSTo/w400-h86/lablogatory.jpg" width="400" /></a></div><p></p><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif;">The nice people at Lablogatory sent a
rather interesting case study on cold agglutinins today. You can read it </span><a href="https://labmedicineblog.com/2024/03/04/hematology-case-study-brrrr-its-cold-outside/" style="font-family: Arial, sans-serif;">by
clicking here</a><span style="font-family: Arial, sans-serif;">.</span></div><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">It illustrates the importance of a high
MCHC, but never forget that the MCHC might be high in absolute terms, or
relative to what it had been previously.</div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">All of which begs the question should we
be running blood counts in a lower temperature than that which we normally do
to pick these up, or should we be running them in a higher temperate so that
this isn’t an issue (<i>assuming that the condition would be picked up on
clinical grounds</i>).</div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">And here’s a tip – when you warm your
samples to run them warmed, don’t use the analyser directly underneath the air
conditioning’s cold air blower. Not that I ever got told to shut up for
pointing that out ten years ago…</div></span></div>
Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-88159597428236036422024-03-01T12:40:00.005+00:002024-03-01T12:40:26.634+00:001 March 2024 (Friday) - BTLP-TACT Exercise<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj9zMf4JWnhbZ-VF_z74LHoQx8h74B0BEEIqZ5hbW9wp_Ukgxl52csOb9iI82lQCtGEfcm6MXB8hhvDEo9nImlfUUdtVRRNYOUKnLjpc_i9M5LR-N7DPol6Zk243o_uB_D40LykSUk77e3pakGnEQrM6KVnwOuTaHqBBXB99esiH8IoA2WDKLy0disGh-I/s700/btlptact.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="248" data-original-width="700" height="141" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj9zMf4JWnhbZ-VF_z74LHoQx8h74B0BEEIqZ5hbW9wp_Ukgxl52csOb9iI82lQCtGEfcm6MXB8hhvDEo9nImlfUUdtVRRNYOUKnLjpc_i9M5LR-N7DPol6Zk243o_uB_D40LykSUk77e3pakGnEQrM6KVnwOuTaHqBBXB99esiH8IoA2WDKLy0disGh-I/w400-h141/btlptact.jpg" width="400" /></a></div><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif;">It has to be said that I get rather
frustrated with the </span><a href="https://tact.ukneqasbtlp.org.uk/" style="font-family: Arial, sans-serif;">BTLP-TACT
simulator</a><span style="font-family: Arial, sans-serif;">. It could be such a good thing but it is most definitely a work
in progress on which all work seems to have stopped. As was illustrated today.</span></div><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">But I had a go… It gave me one case – a nineteen
year old woman with factor VIII deficiency needing cryoprecipitate tomorrow.</div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">She grouped as O Rh(D) Positive with a
negative antibody screen.</div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">But section 5.5.3 of <a href="https://haemophilia.org.uk/wp-content/uploads/pdf/WFH-Guidelines-for-the-Management-of-Hemophilia-3rd-edition.pdf">the
latest guidelines</a> says “<i>For patients with hemophilia, cryoprecipitate is
not recommended due to concerns about the safety and quality… The use of
cryoprecipitate can only be justified in situations where clotting factor
concentrates are not available as there is no proven advantage for their use
over CFCs. It is strongly encouraged that viral-inactivation procedures be
used, if available</i>”.</div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">So bearing in mind the stuff wasn’t
needed until tomorrow I didn’t issue cryoprecipitate. Plenty of time to get the
proper stuff.</div> </span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">But how was I supposed to put this onto
the exercise? I chose not to select the issue at all as I’ve not seen any
option to cancel it once requested. In reality we would have a conversation
with the requestor.</div><div style="text-align: justify;"><br /></div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">It would seem not requesting the stuff
was the right option as I got the green light.</div></span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-40392796933742002282024-03-01T10:28:00.004+00:002024-03-01T10:28:22.038+00:0029 February 2024 (Thursday) - UKAS Update<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi_U5rNggYMZs5OJKR_9-FK-JQtAp9z7qryiTmlIp_O7g9blVNOAB8Wf0eXf5FyG26rfdzcjCaQeBZAQ4pGLt0asGcOW7QZCrL2QCDV34dcawHo5LgJZ8leXKDK17cLEGYZNSL1XZ2BGj3eZRw6uUUOI3cnu8wTkPq7_OSn-5EQSrQXjAaj8_3uXNPqVgo/s259/ukas1.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="131" data-original-width="259" height="131" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi_U5rNggYMZs5OJKR_9-FK-JQtAp9z7qryiTmlIp_O7g9blVNOAB8Wf0eXf5FyG26rfdzcjCaQeBZAQ4pGLt0asGcOW7QZCrL2QCDV34dcawHo5LgJZ8leXKDK17cLEGYZNSL1XZ2BGj3eZRw6uUUOI3cnu8wTkPq7_OSn-5EQSrQXjAaj8_3uXNPqVgo/s1600/ukas1.jpg" width="259" /></a></div><p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">The UK Accreditation Service sent their
update today… You can <a href="https://e-ukas.com/cr/AQigjBUQ57gQGOmH4xKldU6KJ_yByMzxqnrQa61jgtmC4SNOVP_pShTK1ZEK0A">see
it here</a>. Am I being incredibly cynical in wondering if they might benefit
from taking that <a href="https://www.coursera.org/learn/quality-healthcare/home/week/1">quality
management course</a> I did recently?<o:p></o:p></span></p><div style="text-align: justify;"><br /></div><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-672953264047679272024-03-01T10:23:00.003+00:002024-03-01T10:23:32.267+00:0026 February 2024 (Tuesday) - Transfusion Evidence Alert Update<div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjJ-1zQbe4_DU3MxFIAsT5-4x03KDpL6qaA9K8PhhoMdUJ5n8-SqP3y_tWZgh6ZCgWQdfwvn_61SXq7eXSOEZIDetflKjvlPbMbPHVmH9gH0udP201rNsWHxpJFM_ex6MM-CblyaoNOIOVK7buzxsR4ZYznvJHXBYOmNVsl8LqqduIMl5KygZ4EBjBQdu4/s634/tea.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="137" data-original-width="634" height="86" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjJ-1zQbe4_DU3MxFIAsT5-4x03KDpL6qaA9K8PhhoMdUJ5n8-SqP3y_tWZgh6ZCgWQdfwvn_61SXq7eXSOEZIDetflKjvlPbMbPHVmH9gH0udP201rNsWHxpJFM_ex6MM-CblyaoNOIOVK7buzxsR4ZYznvJHXBYOmNVsl8LqqduIMl5KygZ4EBjBQdu4/w400-h86/tea.jpg" width="400" /></a></div><p class="MsoNormal"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">The people at Transfusion Evidence Alert
sent their update today. In a novel break with tradition there was no mention
of tranexamic acid…<o:p></o:p></span></p><table border="0" cellpadding="0" cellspacing="0" class="x_w580" style="background-color: white; color: #242424; font-family: HelveticaNeue, sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 15px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; width: 580px;"><tbody><tr style="border-collapse: collapse;"><td class="x_w580" style="border-collapse: collapse;" width="580"><p align="left" class="x_article-title" style="color: rgb(217, 43, 52) !important; font-size: 18px; font-weight: bold; line-height: 24px; margin-bottom: 18px; margin-top: 0px;">ARTICLE OF THE MONTH</p><div align="left" class="x_article-content" style="border: 0px; color: rgb(68, 68, 68) !important; font-family: HelveticaNeue, sans-serif, serif, EmojiFont; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 13px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: 18px; margin: 0px 0px 18px; padding: 0px; vertical-align: baseline;"><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="12" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-x%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857905262%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=lTgS%2Bu2XhO2eqiU1S5joU6Pb3O1po0wRxD3%2FqnHQCA4%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-x/" rel="noopener noreferrer" shash="IS9xHuwy4vlVpguVYuHJRq/ump7K+QgS2ISVe9hQkoTCdpzSPNkGWnna32cQH9zj4BnauyXSUKGS4UAJwNsmH0oPufW2Yrj9bm0MGj/drFpQrKqo0X9LyGqIjuQ+AWI8VR3GY4QQRVHxDiFC6MVjcTRmehMg+Vp86CjJJxE5sEg=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-x/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta-analysis.</span></a><br aria-hidden="true" style="line-height: 13px;" />Gibbs, V.N., et al. (2024). <em>The Cochrane Database of Systematic Reviews.</em><br aria-hidden="true" style="line-height: 13px;" /><a data-auth="Verified" data-linkindex="13" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-m%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857912272%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=5wDi6YVaNTylsDolyoc68yv5YKD9f7fIHVsc26LZvr8%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-m/" rel="noopener noreferrer" shash="zEwxIBo1wciMeDaAvpfzM2yRUrCaN5TyxWrR/8TnIr4nY4NW2R87aQ8RODZz66omnr7I+bgdggnl7T9OPMdfH+PUptVebPgN5EjSdqFpKbLmFSTS35i6jzjRsTz9na3TJ2yuWMJo9y+Pa76cJFPYWPloepPAILA8lYHtwFzaevA=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-m/. Click or tap if you trust this link."><span style="border: 0px; color: rgb(255, 0, 0) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">PICO Summary available</span></a></p><p style="margin-bottom: 15px; text-align: center;"><span style="border: 0px; color: rgb(0, 0, 0) !important; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">+++++</span></p></div></td></tr><tr style="border-collapse: collapse;"><td class="x_w580" height="10" style="border-collapse: collapse;" width="580"></td></tr></tbody></table><p class="MsoNormal"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"></span></p><table border="0" cellpadding="0" cellspacing="0" class="x_w580" style="background-color: white; color: #242424; font-family: HelveticaNeue, sans-serif; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 15px; font-stretch: inherit; font-variant-alternates: inherit; font-variant-east-asian: inherit; font-variant-numeric: inherit; font-variant-position: inherit; font-variation-settings: inherit; line-height: inherit; width: 580px;"><tbody><tr style="border-collapse: collapse;"><td class="x_w580" style="border-collapse: collapse;" width="580"><p align="left" class="x_article-title" style="color: rgb(217, 43, 52) !important; font-size: 18px; font-weight: bold; line-height: 24px; margin-bottom: 18px; margin-top: 0px;">TOP ARTICLES</p><div align="left" class="x_article-content" style="border: 0px; color: rgb(68, 68, 68) !important; font-family: HelveticaNeue, sans-serif, serif, EmojiFont; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 13px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: 18px; margin: 0px 0px 18px; padding: 0px; vertical-align: baseline;"><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="14" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-c%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857919410%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=gl95scsS91rlee5rPFS21Y27U9qprnrbnytpRI44Xoo%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-c/" rel="noopener noreferrer" shash="X5ez07siOJ9TNlqrbluHuAf13zu0yM821G9DB9d2L+myr08BJxutG1OSWRcdcmcwWEws81Maq16Z/sS9AyjynPMjDNtEJtuDuQILCJQUeppHpZ6naQQ3kcznbSAGRxeVB0DCpACRrhVRmUxi1CeIyRhI/rih3xkXRuKlwY+UTzQ=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-c/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Standard of care versus octreotide in angiodysplasia-related bleeding (the OCEAN study): a multicenter randomized controlled trial.</span></a><br aria-hidden="true" style="line-height: 13px;" />Goltstein, L., et al. (2023). <em>Gastroenterology. [Record in progress].</em><br aria-hidden="true" style="line-height: 13px;" /><br aria-hidden="true" style="line-height: 13px;" /><a data-auth="Verified" data-linkindex="15" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-q%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857926440%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=J9soVJkhyWZIR43Opqlk5C0yXyr9B0n1YtYEih3XooY%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-q/" rel="noopener noreferrer" shash="UyYCj7FcQoBKfS2f8xyFBxRJiTjg1+DntwQDlsEaNOThr3atIrHkK+qpO5UnLsLnLtVSCNWgpO/CcvVvqPHBqqP2niW8AceTPzRMeUsZj1mBhozjLWy7XyJuI5vHDeYJjNsPihZUBgyadiGQwLz1kzB2K9y7+SQCZOhQjjt/e3c=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-q/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Long-term outcomes of plasma exchange versus intravenous immunoglobulin for the treatment of Guillain-Barré Syndrome: a double-blind, randomized clinical trial.</span></a><br aria-hidden="true" style="line-height: 13px;" />Haridy, N.A., Shehab, M.M., and Khedr, E.M., (2024). <em>Restorative Neurology and Neuroscience.</em></p><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="16" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-a%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857933440%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=eYTXHI6K4iTEHdYP4fXosvLAIm9Hc%2B9zvOkfBVbcS3s%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-a/" rel="noopener noreferrer" shash="FAjdv0DUWV6qeWq/NS0t3096sh977qfMb4VufJ263NiVXCje37aW7VVqtPlBKvqzVNwKuzgfolneVdcvK/ZwiUTY2xAf7WqkNRSbys9R5WUUtehvgM3c1kbHmY/Eqaw5PygJ71DoWOcBX6cjed7CrhWFSKY0cdj++XsJi2PzfJw=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-a/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Iron and erythropoietin to heal and recover after intensive care (ITHRIVE): a pilot randomised clinical trial.</span></a><br aria-hidden="true" style="line-height: 13px;" />Litton, E., et al. (2023). <em>Critical Care and Resuscitation.</em></p><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="17" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-yh%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857940439%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=Hu1LWIn7Z7dVsoxy01vxOTI%2BrV0kSqVaZHuwmUCoe6A%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-yh/" rel="noopener noreferrer" shash="qIZMg5zZjXB7Hxbfo+6A7CCQuoJ4HmUmNsXMwj8eELbosR2bi97HlopG7nstx4Kh7mus0bsQ8mE4yKhgrczbkTT7YY/FTAadiwcSXYYX1YI63ItkFDIlytXcr53ZerNNON3cja/licp3Z2xfcKOowmW7k8gKkBkLQJI0pCRQOZo=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-yh/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Prevention strategies for vasovagal reaction in whole blood donors: a quadri-armed randomised control trial.</span></a><br aria-hidden="true" style="line-height: 13px;" />Meher, R., et al. (2024). <em>Transfusion Medicine. [Record in progress].</em><br aria-hidden="true" style="line-height: 13px;" /><br aria-hidden="true" style="line-height: 13px;" /><a data-auth="Verified" data-linkindex="18" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-yk%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857947446%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=OqoM2bvb3cSpWGcUw2cMUWOEofCansBdNVtWILNM0aQ%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-yk/" rel="noopener noreferrer" shash="W7tzkrYr1Am4bSwfbD9xl4nyPICO9ENzB6qQAuJFdoEQzx9rEuvLresZL5MqJv5mfRCMkh5+cofMiXFh9ctT8IafcxnVMHynGz/s3YAJ3k+TroBGhIA4f+gaCAeuM/RUIuSBjLGQCXWS6ECU8LEDjyvvoLoqup7TRWPmh9N4pLo=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-yk/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Efficacy and cost-effectiveness of darbepoetin alfa once every 4 weeks versus continuous erythropoietin receptor activator once every 4 weeks for anemia correction in patients with chronic kidney disease not on dialysis.</span></a><br aria-hidden="true" style="line-height: 13px;" />Park, G.N., et al. (2024). <em>Kidney Research and Clinical Practice. [Record in progress].</em></p><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="19" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-yu%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857954451%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=vGYH7fqjH0fWvx7vmaegEXXsiv4TZSlqDQOKJ1vNHfE%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-yu/" rel="noopener noreferrer" shash="POFgTxfrojLorKMu0pAbzPSmeooXuijqUL3xE2tWrrTm7+pJADECIDIE4f6gw2zkD4CBpQOL7lkEm1r3MuWHZXz0HLFtmPzf3vdAuYVLtDqEKqV8RRwkU9EGWkvl0i5pJGveUUXah8aTdwdW4sPhfC2weopKGQ+q1T/GJ2XciVU=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-yu/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Effective management of foetal anaemia in Rh(D) alloimmunised pregnant women with intrauterine transfusion: a systematic review.</span></a><br aria-hidden="true" style="line-height: 13px;" />Prescott, B. and D.E. Jackson (2023). <em>Hematology, Transfusion and Cell Therapy. [Record in progress].</em></p><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="20" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-jr%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857961462%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=0K3KPrRotOGhG%2Fr9pnw2ZNn8t8swlMi63VP3ovTXLWg%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-jr/" rel="noopener noreferrer" shash="fDvmwF0PjySbHPOZqFn6Q8IZXI0ijwQqBA81KW1vr9LU1a7L2szMhm6jnFb3rwmti0msKSKuGeJ4dA+X7+vHUyVKD5wtqROcWkcTfHAZMHffZJl32+zoKDyN1j0BdWquuWF9G503qLKz0YxpwRw/76+C7CSLS6W6u3G+5mDc3XM=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-jr/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Reported outcomes in patients with iron deficiency or iron deficiency anemia undergoing major surgery: a systematic review of outcomes.</span></a><br aria-hidden="true" style="line-height: 13px;" />Stangl, S., et al. (2024). <em>Systematic Reviews.</em></p><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="21" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-jy%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857968466%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=7%2Bc%2BUPbdNj7HBjRRGN9yAVuiTEth%2Bc1fDSr4oFpMu18%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-jy/" rel="noopener noreferrer" shash="OMLLw6xjjCFEPl/W7x2kCe4E9BYHFhcZmhFkMzzhRWilJBvpKYuxdiRbgiwWEPahArmxa6oh+l8wbaZReKn7cXG46fFKInbOtUjEXgPJO2rqtBKawL8tzGcLivsOm2iOKbE4IILwAXxr5rEEHUrJmEeE0MmCm86dqE/2YqHfAhU=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-jy/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Desmopressin to reduce periprocedural bleeding and transfusion: a systematic review and meta-analysis.</span></a><br aria-hidden="true" style="line-height: 13px;" />Wang, C., et al. (2024). <em>Perioperative Medicine.</em></p><p style="margin-bottom: 15px;"><a data-auth="Verified" data-linkindex="22" href="https://gbr01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fevidentiapublishing.cmail19.com%2Ft%2Ft-l-ezijid-btjdykrlh-jj%2F&data=05%7C02%7Cd.styles%40nhs.net%7C1d49dad830b74927149508dc377093fb%7C37c354b285b047f5b22207b48d774ee3%7C0%7C1%7C638446203857975502%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C60000%7C%7C%7C&sdata=hfBpJ3t2iBPrPsTxd%2BMH%2Fcsf1RP0YB8gIfaNrR0cNNA%3D&reserved=0" originalsrc="https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-jj/" rel="noopener noreferrer" shash="DcOTkn7Uy3IuIajSasKdOJTvEspp+XRsRQDZ2QZi2np+UAmsMtONuX/FLQVdNJZttL7Bm0nCBUN+gpTAQ0xKfdUWtccwLE8pv9vgQNfQyyjn+HTi2pYzbREd+LQuRYujYw5euaLryXM7Q5iCp9WkMUYedR1CEuuLIRkuNTpItk0=" style="border: 0px; color: rgb(34, 87, 153) !important; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: inherit; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: bold; line-height: inherit; margin: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank" title="Original URL: https://evidentiapublishing.cmail19.com/t/t-l-ezijid-btjdykrlh-jj/. Click or tap if you trust this link."><span style="border: 0px; color: inherit; font-family: inherit; font-feature-settings: inherit; font-kerning: inherit; font-optical-sizing: inherit; font-size: 16px; font-stretch: inherit; font-style: inherit; font-variant: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">Effects of albumin and crystalloid priming strategies on red blood cell transfusions in on-pump cardiac surgery: a network meta-analysis.</span></a> Wang, T., et al. (2024). <em>BMC Anesthesiology.</em></p><p style="margin-bottom: 15px; text-align: center;"><span style="border: 0px; color: inherit; font: inherit; margin: 0px; padding: 0px; vertical-align: baseline;">+++++</span></p></div></td></tr></tbody></table><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-79402439475566164442024-03-01T10:18:00.001+00:002024-03-01T10:18:08.519+00:0023 February 2024 (Friday) - Oncology Central Update<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi6F0StBwDkWhdUskGuGMZPyGw_Uct3iZs5MsyU7GSxQ_5ddJVLfcFHxzL61opMUog2eG3UqSbY5uKsqEccIElW6xwvBnELcVHuODmPytvPdXgyAviz6Uf5LO8CqZsNilT7ISLooGMjAQtZ-HzQ0PUFnRe_hwWSo0-OooZ-ZVpEVgCZzjbaS-17ZERKb7g/s531/oncology%20central.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="71" data-original-width="531" height="86" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi6F0StBwDkWhdUskGuGMZPyGw_Uct3iZs5MsyU7GSxQ_5ddJVLfcFHxzL61opMUog2eG3UqSbY5uKsqEccIElW6xwvBnELcVHuODmPytvPdXgyAviz6Uf5LO8CqZsNilT7ISLooGMjAQtZ-HzQ0PUFnRe_hwWSo0-OooZ-ZVpEVgCZzjbaS-17ZERKb7g/w640-h86/oncology%20central.jpg" width="640" /></a></div><div style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">The nice people at Oncology Central sent
their update today. All a bit over my head, but stuff I need to be aware of… </span></div><br /><p></p><div class="hse-section" id="module_1697031113143" style="background-color: #eaf0f6; font-family: Helvetica, Arial, sans-serif; font-size: 15px; padding-left: 10px; padding-right: 10px;"><div bgcolor="#ffffff" class="hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; margin-left: auto; margin-right: auto; max-width: 600px; min-width: 280px; width: 600px !important;"><div class="hse-column hse-size-6" id="module_1697031113143_1" style="display: table-cell; max-width: 300px !important; vertical-align: top; width: 300px !important;"><table cellpadding="0" cellspacing="0" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td class="hs_padded" style="border-collapse: collapse; font-size: 15px; padding: 10px 15px 10px 20px; word-break: break-word;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="hs_cos_wrapper_module_16970311131173" style="color: inherit; font-size: inherit; line-height: inherit;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_rich_text" data-hs-cos-general-type="widget" data-hs-cos-type="rich_text" id="hs_cos_wrapper_module_16970311131173_" style="color: inherit; font-size: inherit; line-height: inherit;"><p style="line-height: 26.25px; margin: 0px;"><a data-hs-link-id="0" href="https://www.oncology-central.com/podcasts/uncovering-the-link-between-cancer-disparities-and-climate-change/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd; font-weight: bold;" target="_blank">Uncovering the link between cancer disparities and climate change</a></p><p style="line-height: 26.25px; margin: 0px;"> </p><p style="line-height: 26.25px; margin: 0px;">What disparities exist in cancer screening and how does this impact patient outcomes? Listen to our latest podcast episode with Dr Kilan Ashad-Bishop from the American Cancer Society to find out.</p></div></div></td></tr></tbody></table></div><div class="hse-column hse-size-6" id="column_1707203418155_1" style="display: table-cell; max-width: 300px !important; vertical-align: top; width: 300px !important;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="hs_cos_wrapper_module_17072034181152" style="color: inherit; font-size: inherit; line-height: inherit;"><table cellpadding="0" cellspacing="0" class="hse-image-wrapper" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td align="center" class="hs_padded" style="border-collapse: collapse; font-size: 0px; padding: 10px 20px; text-align: center; word-break: break-word;" valign="top"><a data-hs-link-id="1" href="https://www.oncology-central.com/podcasts/uncovering-the-link-between-cancer-disparities-and-climate-change/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" style="color: #00a4bd;" target="_blank"><img align="middle" alt="climate change disparities" sizes="(max-width: 200px) 100vw, 200px" src="https://info.oncology-central.com/hs-fs/hubfs/Jade%20OC%20NL%20feature%20image.png?upscale=true&width=400&upscale=true&name=Jade%20OC%20NL%20feature%20image.png" srcset="https://info.oncology-central.com/hs-fs/hubfs/Jade%20OC%20NL%20feature%20image.png?upscale=true&width=400&upscale=true&name=Jade%20OC%20NL%20feature%20image.png 200w, https://info.oncology-central.com/hs-fs/hubfs/Jade%20OC%20NL%20feature%20image.png?upscale=true&width=800&upscale=true&name=Jade%20OC%20NL%20feature%20image.png 400w" style="border: none; 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font-weight: bold;" target="_blank"><span style="color: #e37d22;">READ MORE >>></span></a></p><p style="font-size: 14px; line-height: 17.5px; margin: 0px;"> </p></div></div></td></tr></tbody></table></div></div></div><div class="hse-section" id="module_1686753552064" style="background-color: #eaf0f6; font-family: Helvetica, Arial, sans-serif; font-size: 15px; padding-left: 10px; padding-right: 10px;"><div bgcolor="#ffffff" class="hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; margin-left: auto; margin-right: auto; max-width: 600px; min-width: 280px; width: 600px !important;"><div class="hse-column hse-size-12" id="module_1686753552064_0" style="display: table-cell; max-width: 600px !important; vertical-align: top; width: 600px !important;"><table cellpadding="0" cellspacing="0" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td class="hs_padded" style="border-collapse: collapse; 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border-collapse: collapse; border-spacing: 0px; margin-left: auto; margin-right: auto; max-width: 600px; min-width: 280px; width: 600px !important;"><div class="hse-column hse-size-12" id="column_1706105949799_0" style="display: table-cell; max-width: 600px !important; vertical-align: top; width: 600px !important;"><table cellpadding="0" cellspacing="0" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td class="hs_padded" style="border-collapse: collapse; font-size: 15px; padding: 10px 20px; word-break: break-word;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="hs_cos_wrapper_module_16818973914444" style="color: inherit; font-size: inherit; line-height: inherit;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_rich_text" data-hs-cos-general-type="widget" data-hs-cos-type="rich_text" id="hs_cos_wrapper_module_16818973914444_" style="color: inherit; font-size: inherit; line-height: inherit;"><p style="line-height: 26.25px; margin: 0px;"><a data-hs-link-id="0" href="https://www.futuremedicine.com/doi/10.2217/fon-2023-0421?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd; font-weight: bold;" target="_blank">Real-world clinical scenarios during introduction of trastuzumab biosimilar for HER2-positive breast cancer in the European Union</a></p><p style="line-height: 26.25px; margin: 0px;">Trastuzumab-anns is a biosimilar to trastuzumab, which is approved by the EMA and US FDA for treatment of HER2+ early and metastatic breast cancer. Read about its use in seven clinical oncology practices in the EU.</p><p style="line-height: 26.25px; margin: 0px;"><a data-hs-link-id="1" href="https://www.futuremedicine.com/doi/10.2217/fon-2023-0421?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd; font-weight: bold;" target="_blank"><span style="color: #e37d22;">MORE >>></span></a></p></div></div></td></tr></tbody></table></div></div></div><div class="hse-section" id="module_1692781429580" style="background-color: #eaf0f6; font-family: Helvetica, Arial, sans-serif; font-size: 15px; padding-left: 10px; padding-right: 10px;"><div bgcolor="#ffffff" class="hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; margin-left: auto; margin-right: auto; max-width: 600px; min-width: 280px; width: 600px !important;"><div class="hse-column hse-size-12" id="module_1692781429580_1" style="display: table-cell; max-width: 600px !important; vertical-align: top; width: 600px !important;"><table cellpadding="0" cellspacing="0" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td class="hs_padded" style="border-collapse: collapse; font-size: 15px; padding: 10px 20px; word-break: break-word;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="hs_cos_wrapper_module_16927814295534" style="color: inherit; font-size: inherit; line-height: inherit;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_rich_text" data-hs-cos-general-type="widget" data-hs-cos-type="rich_text" id="hs_cos_wrapper_module_16927814295534_" style="color: inherit; font-size: inherit; line-height: inherit;"><p style="line-height: 22.5px; margin: 0px;"><a data-hs-link-id="0" href="https://www.oncology-central.com/how-are-patients-being-put-first-in-a-new-era-of-common-sense-oncology/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" style="color: #00a4bd;" target="_blank"></a></p><p style="line-height: 26.25px; margin: 0px;"><a data-hs-link-id="0" href="https://www.oncology-central.com/bipoc-involvement-in-oncological-research-insights-from-future-oncology/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd; font-weight: bold;" target="_blank">BIPOC involvement in oncological research: insights from Future Oncology</a></p><p style="line-height: 26.25px; margin: 0px;">In this special edition of editor’s highlights, Michael Bell Managing Editor, looks at three articles published over the last 12 months in <em>Future Oncology</em>, concerning greater engagement and representation for Black, Indigenous and People of Colour (BIPOC) people in oncological research.</p><p style="line-height: 26.25px; margin: 0px;"><a data-hs-link-id="1" href="https://www.oncology-central.com/bipoc-involvement-in-oncological-research-insights-from-future-oncology/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank"><span style="color: #ff9100;"><span style="color: #e37d22;"><span style="font-weight: bold;">MORE</span> >>></span></span></a></p></div></div></td></tr></tbody></table></div></div></div><div class="hse-section" id="module_1700647409338" style="background-color: #eaf0f6; font-family: Helvetica, Arial, sans-serif; font-size: 15px; padding-left: 10px; padding-right: 10px;"><div bgcolor="#ffffff" class="hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; margin-left: auto; margin-right: auto; max-width: 600px; min-width: 280px; width: 600px !important;"><div class="hse-column hse-size-12" id="module_1700647409338_0" style="display: table-cell; max-width: 600px !important; vertical-align: top; width: 600px !important;"><table cellpadding="0" cellspacing="0" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td class="hs_padded" style="border-collapse: collapse; font-size: 15px; padding: 10px 20px; word-break: break-word;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="hs_cos_wrapper_module_17006474092791" style="color: inherit; font-size: inherit; line-height: inherit;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_rich_text" data-hs-cos-general-type="widget" data-hs-cos-type="rich_text" id="hs_cos_wrapper_module_17006474092791_" style="color: inherit; font-size: inherit; line-height: inherit;"><p style="line-height: 26.25px; margin: 0px;"><a data-hs-link-id="0" href="https://www.futuremedicine.com/doi/10.2217/fon-2022-1192?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd; font-weight: bold;" target="_blank">P-REALITY X: prolonging metastatic breast cancer survival by adding palbociclib to an aromatase inhibitor</a></p><p style="line-height: 26.25px; margin: 0px;">Find out details of a real-world database analysis exploring how adding palbociclib to an aromatase inhibitor could prolong the life of people with metastatic HR+/HER2– breast cancer in routine clinical practice. </p><p style="line-height: 26.25px; margin: 0px;"><span style="color: #e37d22;"><a data-hs-link-id="1" href="https://www.futuremedicine.com/doi/10.2217/fon-2022-1192?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #e37d22; font-weight: bold;" target="_blank">MORE >>></a></span></p></div></div></td></tr></tbody></table></div></div></div><div class="hse-section" id="section_1707209261007" style="background-color: #eaf0f6; font-family: Helvetica, Arial, sans-serif; font-size: 15px; padding-left: 10px; padding-right: 10px;"><div bgcolor="#ffffff" class="hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; margin-left: auto; margin-right: auto; max-width: 600px; min-width: 280px; width: 600px !important;"><div class="hse-column hse-size-12" id="column_1707209261007_0" style="display: table-cell; max-width: 600px !important; vertical-align: top; width: 600px !important;"><table cellpadding="0" cellspacing="0" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td class="hs_padded" style="border-collapse: collapse; font-size: 15px; padding: 10px 20px; word-break: break-word;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="hs_cos_wrapper_module_17072092609468" style="color: inherit; font-size: inherit; line-height: inherit;"><table align="center" border="0" cellpadding="0" cellspacing="0" role="presentation" style="border-spacing: 0px !important;"><tbody><tr><td align="center" bgcolor="#00a4bd" style="background-color: #00a4bd; border-collapse: collapse; border-radius: 8px; cursor: auto; font-size: 15px; word-break: break-word;" valign="middle"><a data-hs-link-id="0" href="https://www.oncology-central.com/journal-articles/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" style="color: #00a4bd; display: block; font-family: Arial, sans-serif; font-size: 16px; margin: 0px; padding: 12px 18px; text-decoration-line: none;" target="_blank"><span style="color: white;">Discover more journal content</span></a></td></tr></tbody></table></div></td></tr></tbody></table></div></div></div><div class="hse-section" id="section_1707203364823" style="background-color: #eaf0f6; font-family: Helvetica, Arial, sans-serif; font-size: 15px; padding-left: 10px; padding-right: 10px;"><div bgcolor="#ffffff" class="hse-column-container" style="background-color: white; border-collapse: collapse; border-spacing: 0px; margin-left: auto; margin-right: auto; max-width: 600px; min-width: 280px; width: 600px !important;"><div class="hse-column hse-size-12" id="column_1707203364824_0" style="display: table-cell; max-width: 600px !important; vertical-align: top; width: 600px !important;"><div class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" data-hs-cos-general-type="widget" data-hs-cos-type="module" id="hs_cos_wrapper_module_16976438069101" style="color: inherit; font-size: inherit; line-height: inherit;"><table cellpadding="0" cellspacing="0" class="hse-image-wrapper" role="presentation" style="border-collapse: collapse; border-spacing: 0px !important; width: 100%;"><tbody><tr><td align="center" class="hs_padded" style="border-collapse: collapse; font-size: 0px; padding: 10px 20px; text-align: center; word-break: break-word;" valign="top"><a data-hs-link-id="0" href="https://www.accc-cancer.org/home/about/awards/accc-innovator-awards/accc-innovator-awards-2024?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" style="color: #00a4bd;" target="_blank"><img align="middle" alt="ACCC awards" sizes="(max-width: 560px) 100vw, 560px" src="https://info.oncology-central.com/hs-fs/hubfs/ACCC%20awards.jpg?upscale=true&width=1120&upscale=true&name=ACCC%20awards.jpg" srcset="https://info.oncology-central.com/hs-fs/hubfs/ACCC%20awards.jpg?upscale=true&width=1120&upscale=true&name=ACCC%20awards.jpg 560w, https://info.oncology-central.com/hs-fs/hubfs/ACCC%20awards.jpg?upscale=true&width=2240&upscale=true&name=ACCC%20awards.jpg 1120w" style="border: none; font-size: 16px; max-width: 100%; outline: none; text-decoration-line: none;" width="560" 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href="https://www.oncology-central.com/clinical-trials/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Clinical trials</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/drug-approvals/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Drug approvals</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/drug-development/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Drug development</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/diagnostics/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Diagnostics</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/epidemiology/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Epidemiology</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/genetics-and-genomics/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Genetics and genomics</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/immuno-oncology/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Immuno- oncology</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/industry-and-business/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Industry and business</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/patient-perspective/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Patient perspective</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/personalized-and-precision-medicine/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Personalized medicine</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/preclinical-research-and-trials/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Preclinical research and trials</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/prevention-and-screening/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Prevention and screening</a> | <a data-hs-link-id="0" href="https://www.oncology-central.com/targerted-therapies/?utm_campaign=Oncology%20Central%20-%20weekly%20newsletters&utm_source=hs_email&utm_medium=email&utm_content=295054023&_hsenc=p2ANqtz-8-k7A_amrESpWAPfQ6Uh9KB3vkh-oLKuntQF0zCy99-rQ7-_-EbMxEofW8JYvC9cl4BALlQOkxZ1l3alHP2M29skSOyQ" rel="noopener" style="color: #00a4bd;" target="_blank">Targeted therapies</a> |</p></div></div></td></tr></tbody></table></div></div></div>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-42641840243250032892024-03-01T10:13:00.004+00:002024-03-01T10:13:29.526+00:0020 February 2024 (Tuesday) - Westgard QC Update<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhGK4n9chgddzyOaT9Kagg56UGdK5N-O9n1PhXcY77_e0cdCS3RCHslz7SXeSuCzI3TfchsvnWGUxoTUjnT_0OtiPdbJ3Rv7Wm6AyOtC5AQgxWuCBJhgUhYjvY8ur2G-Xlfe8AfW8GsSP4Y7YSE-R9V12gqQthKWHw_LGDx8o2F_t3oH1kcfCOO24yCnao/s1860/wesgard.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="200" data-original-width="1860" height="43" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhGK4n9chgddzyOaT9Kagg56UGdK5N-O9n1PhXcY77_e0cdCS3RCHslz7SXeSuCzI3TfchsvnWGUxoTUjnT_0OtiPdbJ3Rv7Wm6AyOtC5AQgxWuCBJhgUhYjvY8ur2G-Xlfe8AfW8GsSP4Y7YSE-R9V12gqQthKWHw_LGDx8o2F_t3oH1kcfCOO24yCnao/w400-h43/wesgard.jpg" width="400" /></a></div><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt; mso-ansi-language: EN-US; mso-bidi-language: AR-SA; mso-fareast-font-family: SimSun; mso-fareast-language: EN-US;"><div style="text-align: justify;"><span style="font-size: 12pt;">The nice people at Westgard
</span><a href="https://mailchi.mp/westgard/2024-lowering-standards?e=f360010e84" style="font-size: 12pt;">sent
out their update</a><span style="font-size: 12pt;"> today. All perhaps a tad dull, but this is the sort of
thing which is relevant to my daily round. The article on the measurement of
uncertainty was rather useful. A shame that not everyone who needs to read it
will read it.</span></div></span><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-34239335416248164802024-03-01T10:07:00.003+00:002024-03-01T10:07:16.517+00:0019 February 2024 (Monday) - European Hematology Association Update<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgSirBYvnqrnNiiew33lmPJ5bA9iSbvhwE7wyDIREVqC_BWWIJDH8rrRkYwWS3X_tkkDyKutIgYJgfXUED9Rswy-W72Wb46Jv1Eyw4O1g5WGyC713YcSMX1nE8Ucd1NjmnoOxNuhHcRMF3XGMHnfgU4-iQk4F-WaomwUvHRvc1geR4twqw1zcQ-MHnP9aU/s1466/EHA1.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="1466" data-original-width="1038" height="320" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgSirBYvnqrnNiiew33lmPJ5bA9iSbvhwE7wyDIREVqC_BWWIJDH8rrRkYwWS3X_tkkDyKutIgYJgfXUED9Rswy-W72Wb46Jv1Eyw4O1g5WGyC713YcSMX1nE8Ucd1NjmnoOxNuhHcRMF3XGMHnfgU4-iQk4F-WaomwUvHRvc1geR4twqw1zcQ-MHnP9aU/s320/EHA1.jpg" width="227" /></a></div><p></p><p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">On the one hand following the European
Hematology Association’s Facebook feed is a good move as they send out things
like this. On the other hand what with the vagaries of Facebook, there’s very
little point in doing a morphology quiz on-line as when the answer comes out,
the Facebook algorithms will decide to show me pictured of Lego or dogs instead…<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">In this instance platelet clumping
should warrant performing<span style="mso-spacerun: yes;"> </span>blood count on
a citrated sample.<o:p></o:p></span></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-61969282731689590802024-03-01T09:58:00.001+00:002024-03-01T09:58:07.003+00:0015 February 2024 (Thursday) - Horiba update<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjPT_dOGdtqJAuGxAWqSd0uSF_tgpWLxdOEMdiOvRK5b4XnzZjD2dN1804uXuWuyC1ab72xRxXUL4DoUgjmSgEsdY5iKy83gQgs6ojSCe9HZiUN-CQS1An2eAp8cJ2TTUa6Ko-HSxXJK1tKMMbxkrK7J3D_kd_XsO71O8YnRC5Q5layZ_e8sodZuyJ-hrM/s615/horiba.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="128" data-original-width="615" height="84" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjPT_dOGdtqJAuGxAWqSd0uSF_tgpWLxdOEMdiOvRK5b4XnzZjD2dN1804uXuWuyC1ab72xRxXUL4DoUgjmSgEsdY5iKy83gQgs6ojSCe9HZiUN-CQS1An2eAp8cJ2TTUa6Ko-HSxXJK1tKMMbxkrK7J3D_kd_XsO71O8YnRC5Q5layZ_e8sodZuyJ-hrM/w400-h84/horiba.jpg" width="400" /></a></div><p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">The nice people at Horiba sent their
monthly <a href="https://myemail.constantcontact.com/QSP-Blood-Cell-Morphology-Newsletter---Issue-43.html?soid=1113948681393&aid=qrKMyN4WpGk">morphology
update today</a>. There were loads of answers to previous quizzes… not that I
can remember having seen any previous quizzes. I wonder if I’m missing
something here…<o:p></o:p></span></p><div style="text-align: justify;"><br /></div><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-78367496436817519862024-02-14T10:53:00.000+00:002024-02-14T10:53:11.332+00:0014 February 2024 (Wednesday) - Getting the BTLP-TACT Wrong. Again.<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhGhvL2-CqgRmv0NB1aePVeA1_W9QOyl5NioHkSjnKX0ktqDS8iuaD-ifaTZHn9YOHonuYhMHnVtLib7Wlq3TMw9wX4OAw9r_R2ccPvy417BH5qgIgKr57DVLYmcMhGagi5reiFGSAgJ3MO6-yLScIj4tAlbLLoBCS0bsiwe24EvMJI-lRs9JW730auMHk/s700/btlptact.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="248" data-original-width="700" height="141" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhGhvL2-CqgRmv0NB1aePVeA1_W9QOyl5NioHkSjnKX0ktqDS8iuaD-ifaTZHn9YOHonuYhMHnVtLib7Wlq3TMw9wX4OAw9r_R2ccPvy417BH5qgIgKr57DVLYmcMhGagi5reiFGSAgJ3MO6-yLScIj4tAlbLLoBCS0bsiwe24EvMJI-lRs9JW730auMHk/w400-h141/btlptact.jpg" width="400" /></a></div><p></p><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif;">Time for another BTLP-TACT exercise… It
gave me two cases.</span></div><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span></div><blockquote style="border: none; margin: 0px 0px 0px 40px; padding: 0px; text-align: left;"><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"><b>00403</b> – a fifty-eight year-old woman
needing group & save for a hernia repair.</div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">Her blood group was indeterminate as a
positive result in the control tube invalidated the entire blood group.
Apparently.</div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">Fortunately the antibody screen was
negative.</div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"><b>92445</b> – a seventy-six year old woman
needing four units of FFP for reversal of warfarin therapy. Personally I wouldn’t
have used FFP for reversal of warfarin therapy, but presumably the nice people
at BTLP-TACT had already had that argument.</div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">She grouped as A Rh(D) Negative with
antibody panel positive in cell 3. I requested antibody panels. The IAT and
enzyme panels were positive in cell 8 corresponding with anti-Kp(a)</div></span></div><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I issued two units of A Rh(D) Negative
FFP, and two units of A Rh(D) Positive FFP as there was no more A Rh(D)
Negative FFP or any AB Rh(D) Negative FFB</div></span></div></blockquote><div style="text-align: left;"><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I got the thumbs-down. I wasn’t supposed
to issue any plasma at all. Well, I know that. But when I said “<i>presumably
the nice people at BTLP-TACT had already had that argument</i>”, clearly they
hadn’t.</div> </span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;"> </div></span><span lang="EN-US" style="font-family: Arial, sans-serif;"><div style="text-align: justify;">I’m getting fed up trying to
second-guess this software…</div></span></div><p>
</p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-89051199524883178412024-02-13T22:00:00.004+00:002024-02-13T22:01:42.046+00:0013 February 2024 (Tuesday) - Eighty Four Point Five Per Cent<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhDJPka5gLWiBlTbagiAM-xyVsttPYoBpDwG7gMnme0uIKVxKGQfVzW6uqaeM2_vyPJv5s7kVQGsUdqn4oZBXR0ryNM36curG0yT5i-A0Tk428CBBp7qWqCNXWPm94ZrXdmjcdQtgAuuklgYs-d12DI0wGbX4KHKkLaQDqCuB2-yXeSvM6D1UmxUYquwro/s774/quality%20course%20result.jpg" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="318" data-original-width="774" height="164" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhDJPka5gLWiBlTbagiAM-xyVsttPYoBpDwG7gMnme0uIKVxKGQfVzW6uqaeM2_vyPJv5s7kVQGsUdqn4oZBXR0ryNM36curG0yT5i-A0Tk428CBBp7qWqCNXWPm94ZrXdmjcdQtgAuuklgYs-d12DI0wGbX4KHKkLaQDqCuB2-yXeSvM6D1UmxUYquwro/w400-h164/quality%20course%20result.jpg" width="400" /></a></div><p></p><div style="text-align: left;"><div style="text-align: justify;"><span style="font-size: medium;"><span face="Arial, sans-serif">I started this quality management course
three weeks ago when I said “</span><i style="font-family: Arial, sans-serif;">I’ve always considered “Quality Management” to
be a load of blah-blah-blah that gets in the way of doing my job, and for years
I’ve been wondering just what I’m missing. I must be missing something.</i></span></div><span style="font-size: medium;"><span face="Arial, sans-serif" lang="EN-US"><div style="text-align: justify;"><i><span lang="EN-US">So far the course has
been nothing but blah-blah-blah, and all it is doing is confirming my
preconceptions.</span></i><span lang="EN-US">”</span></div></span><span face="Arial, sans-serif" lang="EN-US"><div style="text-align: justify;"> </div><o:p><div style="text-align: justify;">I finished the course today and got
eighty four point five per cent. I’ve clearly learned something during this
time, but it has to be said there was a *<i>lot</i>* of “<i>blah-blah-blah”</i>.
It really could have done with a whole lot less general theoretical and a whole
lot more specific practical examples.</div></o:p></span><span face="Arial, sans-serif" lang="EN-US"><div style="text-align: justify;"> </div></span><span face="Arial, sans-serif" lang="EN-US"><div style="text-align: justify;">But eighty four point five per cent is eighty
four point five per cent, isn’t it? There’s something tangible I can stick in a
CPD audit should the need arise.</div></span><span face="Arial, sans-serif" lang="EN-US"><div style="text-align: justify;">The course I’ve just done made it quite
clear that a CPD audit of the sort I’m talking about here in no way contributes
to workplace quality. And that’s why I’m still cynical.</div></span></span></div>
Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-72345228126779031212024-02-13T21:46:00.005+00:002024-02-13T21:46:25.865+00:008 February 2024 (Thursday) - MDS<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhUumI5ipEio_i6j8TDoDn7hiFMh5NJjZ4WJ47C9di8k4VUWe9QRPeSYdCfgXBi1yKsWD4m4G-3G_OmcUqCt1XrJJ3AhZGODHTxhmG0wfcEvwJ1omEdlRNreTsHaEtZQ_i-Z0oi3FrdFkxjEjxgNlB33kGIA9Ffohm5uwv4jKO6KoFAT7YMyjq27sOIxsE/s531/oncology%20central.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="71" data-original-width="531" height="54" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhUumI5ipEio_i6j8TDoDn7hiFMh5NJjZ4WJ47C9di8k4VUWe9QRPeSYdCfgXBi1yKsWD4m4G-3G_OmcUqCt1XrJJ3AhZGODHTxhmG0wfcEvwJ1omEdlRNreTsHaEtZQ_i-Z0oi3FrdFkxjEjxgNlB33kGIA9Ffohm5uwv4jKO6KoFAT7YMyjq27sOIxsE/w400-h54/oncology%20central.jpg" width="400" /></a></div><p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">The nice people at Oncology Central sent
their update today. As always, much of it went over my head, but there was one <a href="https://www.oncology-central.com/does-that-mds-diagnosis-need-a-second-opinion-an-interview-with-mikkael-sekeres/">rather
interesting article</a> about the diagnosis of myelodysplastic syndrome. <o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;">Back in the day MDS was something of a
catch-all labelling of pre-leukaemic conditions. Things are getting a tad more
specific these days<o:p></o:p></span></p><div style="text-align: justify;"><br /></div><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-92091570622579722002024-02-13T21:37:00.007+00:002024-02-13T21:37:48.947+00:007 February 2024 (Wednesday) - Placental Growth Factor<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjK1ZpCpLeKxRFBa77WmOfKWjrs6-Il9abND2dTvTetCDzskAzhqCbcZXa8GRgQvz42GxEFoh3shknLUdMN_rYCMC5PtHp5YiML2TCBU0i7ch4pylEFYsE3wnXcn0AmR7FSpt9jTpwxN65gliNOZbo3aKQcfgJ4lhw8N0KD77HixJ79elNvzxHo5ilpE6s/s249/oxford.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="136" data-original-width="249" height="175" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjK1ZpCpLeKxRFBa77WmOfKWjrs6-Il9abND2dTvTetCDzskAzhqCbcZXa8GRgQvz42GxEFoh3shknLUdMN_rYCMC5PtHp5YiML2TCBU0i7ch4pylEFYsE3wnXcn0AmR7FSpt9jTpwxN65gliNOZbo3aKQcfgJ4lhw8N0KD77HixJ79elNvzxHo5ilpE6s/w320-h175/oxford.jpg" width="320" /></a></div><p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: Arial, sans-serif;">The future? <a href="https://www.healthinnovationoxford.org/our-work/building-on-a-decade-of-health-innovation/safer-pregnancies-pre-eclampsia-test-brings-better-experience-and-productivity-gains/">Here’s
an article</a> about a quick, accurate new blood test for pre-eclampsia which
is contributing to safer pregnancies and better outcomes for tens of thousands
of women and their unborn babies every year.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align: justify;"><span lang="EN-US" style="font-family: Arial, sans-serif;">How long will it be before I’m performing
placental growth factor assays?<o:p></o:p></span></p><div style="text-align: justify;"><br /></div><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-45004899040123005872024-02-13T21:31:00.010+00:002024-02-13T21:31:59.731+00:006 February 2024 (Tuesday) - Fritsma Factor Newsletter<p></p><div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj7rQOQI1Ze1lh4zRLT-VAMyz644HtsUm2EvPwhLzo5Xkvu6LzSJHe9MBdhy4cI5HejvqrJdFr32mb3EiOkE_ELmB1GmxyFMI6TD1IwHIosOOa7AImdCzD8yfkPpmAwv-9DK2IJQ28HKgxtsjNgc_0dGPZKiH3xkWEUscLcypKuioVrfkyhES1FPCyyqUU/s600/fritsma.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="150" data-original-width="600" height="100" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj7rQOQI1Ze1lh4zRLT-VAMyz644HtsUm2EvPwhLzo5Xkvu6LzSJHe9MBdhy4cI5HejvqrJdFr32mb3EiOkE_ELmB1GmxyFMI6TD1IwHIosOOa7AImdCzD8yfkPpmAwv-9DK2IJQ28HKgxtsjNgc_0dGPZKiH3xkWEUscLcypKuioVrfkyhES1FPCyyqUU/w400-h100/fritsma.jpg" width="400" /></a></div><div style="text-align: left;"><div style="text-align: justify;"><span style="font-family: Arial, sans-serif; font-size: 12pt;"><br /></span></div><div style="text-align: justify;"><span style="font-family: Arial, sans-serif; font-size: 12pt;">Cryoprecipitate, platelet function tests…
again the Fritsma Factor newsletter comes up trumps.</span></div><span lang="EN-US" style="font-family: "Arial",sans-serif; font-size: 12.0pt;"><div style="text-align: justify;"><span style="font-size: 12pt;">You can read it </span><a href="https://mailchi.mp/fritsmafactor/6xcd2q5thj-10688073?e=9d23f80dce" style="font-size: 12pt;">by
clicking here</a><span style="font-size: 12pt;">. There’s not lots, but what there is, is good.</span></div></span></div>
<br /><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0tag:blogger.com,1999:blog-5661471869788849946.post-89892518804046029022024-02-03T11:23:00.002+00:002024-02-03T11:24:40.168+00:003 February 2024 (Saturday) - More Quality Management<div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEitX-FZSEBnIMecmVWaZXDAEK15GUCdhoG2oF2yzTRwzZKjMSPpKaxF5sjeS_CgiZZ3ZTbUSQbvaowd5J86OYo80Z145DUQGAwUnZ93hU4JO2vUxvWQTxEI_XAI32zJ6qbQQZlERo85n4DHwoHgf8msjC92ta3WkWEOui4im0AE1-I8lNLiXZZ3j7BcQ28/s795/quality%20course.jpg" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="181" data-original-width="795" height="146" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEitX-FZSEBnIMecmVWaZXDAEK15GUCdhoG2oF2yzTRwzZKjMSPpKaxF5sjeS_CgiZZ3ZTbUSQbvaowd5J86OYo80Z145DUQGAwUnZ93hU4JO2vUxvWQTxEI_XAI32zJ6qbQQZlERo85n4DHwoHgf8msjC92ta3WkWEOui4im0AE1-I8lNLiXZZ3j7BcQ28/w640-h146/quality%20course.jpg" width="640" /></a></div><div style="text-align: justify;"><span style="font-family: arial; font-size: medium;">Having identified a problem... is it really a problem? Was there an error that came to light? Has there been a complaint? Or is there something in the workplace that could be changed easily and that would be used to tick a quality management box?</span></div><div style="text-align: justify;"><span style="font-family: arial; font-size: medium;">Having identified a real (<i>as opposed to imagined or made up for a paperwork exercise</i>) problem, is this one that can be readily rectified? And exactly how can we be sure that what changes we make actually eliminate or reduce the percieved problem?</span></div><div style="text-align: justify;"><span style="font-family: arial; font-size: medium;"><br /></span></div><div style="text-align: justify;"><span style="font-family: arial; font-size: medium;">An example was given from a well-known manucaturer of office equipment who felt they were paying far too much in transport costs when getting stuff in from their suppliers. At the end of the process they cut a list of three thousand suppliers down to three hundred; thereby eliminating the transport and administration costs of dealing with two thousand seven hundred companies. </span></div><div style="text-align: justify;"><span style="font-family: arial; font-size: medium;"><br /></span></div><div style="text-align: justify;"><span style="font-family: arial; font-size: medium;">Suddenly quality management is all making sense.</span></div><p></p>Manky Badgerhttp://www.blogger.com/profile/16051056595105608662noreply@blogger.com0