17 November 2025 (Monday) - Getting the BTLP-TACT Wrong (again)

Time for another BTLP-TACT exercise…
I was presented with two cases:
 

57466 – a forty-two year-old woman needing group and save for a PV bleed.

She grouped as O Rh(D) Negative with a negative antibody screen.

24369 – a sixty-eight year-old chap with hypofibrinogenaemia needing two units of cryo as he was bleeding.

He grouped as A Rh(D) Positive with antibody screen positive in all three cells. I performed antibody panels. The IAT panel was positive in cells 1, 2, 3, 5, 6, 7, 9 and 10 but the enzyme panel was negative throughout. Ideally I’d want to send this off, but from what I could see this was probably anti- S with anti-Fy(a) but I couldn’t exclude anti-K

Cryo *is* recommended in hypofribrinogenaemia so I issued two units of cryo.

 
I got the thumbs down… supposedly a clinically significant antibody was masked by not noted… I’d love to know what it was.

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