29 August 2025 (Friday) - Transfusion Evidence Library Update

Albumin from rice, and two more articles about tranexamic acid. The monthly update from the Transfusion Evidence Library is certainly worth having.

ARTICLE OF THE MONTH

Mitapivat in adults with non-transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE): a phase 3, international, randomised, double-blind, placebo-controlled trial.
Taher, A.T., et al. (2025). Lancet.
PICO SUMMARY

 

 

TOP ARTICLES

Enhancing bleeding reporting in acute coronary syndrome clinical trials: a systematic review of the ABC guidelines adherence.
García-Campa, M., et al. (2025). BMC Cardiovascular Disorders.

Efficacy and safety of tranexamic acid administration for subarachnoid hemorrhage: a systematic review and meta-analysis.
Imai, E., et al. (2025). Frontiers in Neurology.

Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions.
Karafin, M.S., et al. (2025). The Journal of Clinical Investigation. 

Leveraging behavioral sciences to augment voluntary blood donation in China: a randomized control trial and latent class analysis.
Li, B., et al. (2025). International Journal of Behavioral Medicine. [Record in progress].

Inhospital coagulation management and fluid replacement therapy in patients with multiple and/or severe injuries - a systematic review and clinical practice guideline update.
Lier, H., et al. (2025). European Journal of Trauma and Emergency Surgery.

Rice-derived recombinant human serum albumin as an alternative to human plasma for patients with decompensated liver cirrhosis: a randomised, double-blind, positive-controlled and non-inferiority trial.
Niu, J., et al. (2025). Gut.

Randomized double-blind placebo-controlled trial of desmopressin for post-kidney biopsy bleeding.
Prasad, N., et al. (2025). Kidney International Reports.

Effectiveness of prophylactic tranexamic acid in reducing blood loss in children undergoing open nephrectomy for Wilms tumor: a randomized controlled study.
Verma, S., et al. (2025). Cureus.

Comparative efficacy and safety of rhTPO, romiplostim, and eltrombopag in the treatment of pediatric primary immune thrombocytopenia: a systematic review and network meta-analysis.
Zhang, X., et al. (2025). Frontiers in Immunology.