The nice people at the Transfusion
Evidence Library sent their update today. As ever there were a load of
articles, but one caught my eye…
Chantepie, S.P., et al. (2023). Leukemia Research. [Link opens in Transfusion Evidence Library].
A comparison was made between people receiving
two-unit blood transfusions as opposed to single unit transfusions. Back in the
day it was common knowledge that the hazards of a single unit transfusion
outweighed the benefits of that transfusion.
More recently this has been thrown out
as being about as true as the flat earth theory…
However this trial has found that a
single unit transfusion policy is not inferior to a double unit transfusion
policy.
However, the single unit transfusion
policy did not reduce the total number of units transfused per stay. Presumably
people just have smaller transfusions more often.
Is that good or bad? Presumably this
reduces TACO?

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