26 May 2025 (Monday) - Transfusion Evidence Update

The nice people at the Transfusion Evidence Library sent their update today. As always there was a lot to take in. And as ever, that which seems to be showing interesting results today is totally contradicting that which was a complete no-no of ten to fifteen years ago and was standard practice thirty to forty years ago.
Transfusion science really does seem to see-saw between utterly opposed viewpoints. Whole blood transfusions? Good or bad? They can’t have been good forty years ago and good today, but totally wrong twenty years ago?
Iron tablets… how can surveys now show they don’t improve post operative anaemia these days when they always used to?

ARTICLE OF THE MONTH

TOP ARTICLES

The cost-effectiveness of interventions used for the screening, diagnosis and management of anaemia in pregnancy: a systematic review.
Allen, C.L., et al. (2025). PLOS Global Public Health.

Intravenous ferric carboxymaltose in heart failure with iron deficiency: the FAIR-HF2 DZHK05 randomized clinical trial.
Anker, S.D., et al. (2025). JAMA. [Record in progress].

Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency.
Anker, S.D., et al. (2025). Nature Medicine. [Record in progress]. 

Blood transfusion strategies for major bleeding in trauma.
Brunskill, S.J., et al. (2025). The Cochrane Database of Systematic Reviews.

Examining the role of voluntary reciprocal altruism and collectivism interventions in enhancing intentions to donate blood among young non-donors: an experimental study.
Duffy, C. and Molloy, G.J., (2025). Psychology & Health. [Record in progress].

Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis.
Gallos, I.D., et al. (2025). The Cochrane Database of Systematic Reviews.

The use of iron after surgery: a systematic review and meta-analysis.
Lim, J., et al. (2025). Anaesthesia. [Record in progress].               

How low can we go? Comparison of liberal and restrictive red cell transfusion thresholds in paediatric allogeneic haematopoietic stem cell transplantation: A randomized multicentre feasibility trial.
New, H.V., et al. (2025). British Journal of Haematology. [Record in progress].               

Pragmatic O-Positive Whole-blood RandoMizaTion in male trauma Patients (POWeR-MTP).
Strada, A.M., et al. (2025). European Journal of Trauma and Emergency Surgery: official publication of the European Trauma Society.

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