The nice people at the Transfusion
Evidence Library sent their update today. Again tranexamic acid featured several
times, as did the cold storage of platelets….
Top article
Topical versus intravenous tranexamic acid in patients undergoing cardiac surgery: the DEPOSITION randomized controlled trial.
Lamy, A., et al. (2024). Circulation.
PICO SUMMARY
Selected articles
Delayed cold-stored vs. room temperature stored platelet transfusions in bleeding adult cardiac surgery patients-a randomized multicentre pilot study (PLTS-1).
Bartoszko, J., et al. (2024). Pilot and Feasibility Studies.
Hypovolaemic phlebotomy in patients undergoing hepatic resection at higher risk of blood loss (PRICE-2): a randomised controlled trial.
Martel, G., et al. (2025). The Lancet Gastroenterology & Hepatology.
Safety and efficacy of tranexamic acid in general surgery.
Park, L.J., et al. (2025). JAMA Surgery.
A randomised controlled trial assessing the effect of tranexamic acid on post-operative blood transfusions in patient with intra-capsular hip fractures treated with hemi- or total hip arthroplasty.
Khatib, Y., et al. (2024). Archives of Orthopaedic and Trauma Surgery.
Tranexamic acid during radical cystectomy: a randomized clinical trial.
Breau, R.H., et al. (2024). JAMA Surgery.
Evaluating the safety and efficacy of a novel polysaccharide hemostatic system during surgery: a multicenter multispecialty prospective randomized controlled trial.
House, M.G., et al. (2024). Surgery Open Science.
Hospital policy of tranexamic acid to reduce transfusion in major non-cardiac surgery (TRACTION): protocol for a phase IV randomised controlled trial.
Houston, B.L., et al. (2024). BMJ Open.
The effect of perioperative sequential application of multiple doses of tranexamic acid on postoperative blood loss after PLIF: a prospective randomized controlled trial.
Dong, W., et al. (2024). International Journey of Surgery.
Tranexamic acid in patients undergoing liver resection: the HeLiX randomized clinical trial.
Karanicolas, P.J., et al. (2024). JAMA.
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