20 May 2025 (Tuesday) - Transfusion Evidence Library

The nice people at the Transfusion Evidence Library sent their update today. Again tranexamic acid featured several times, as did the cold storage of platelets….

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Selected articles

Delayed cold-stored vs. room temperature stored platelet transfusions in bleeding adult cardiac surgery patients-a randomized multicentre pilot study (PLTS-1).
Bartoszko, J., et al. (2024). Pilot and Feasibility Studies.

Hypovolaemic phlebotomy in patients undergoing hepatic resection at higher risk of blood loss (PRICE-2): a randomised controlled trial.
Martel, G., et al. (2025). The Lancet Gastroenterology & Hepatology.

Safety and efficacy of tranexamic acid in general surgery.
Park, L.J., et al. (2025). JAMA Surgery.

A randomised controlled trial assessing the effect of tranexamic acid on post-operative blood transfusions in patient with intra-capsular hip fractures treated with hemi- or total hip arthroplasty.
Khatib, Y., et al. (2024). Archives of Orthopaedic and Trauma Surgery.

Tranexamic acid during radical cystectomy: a randomized clinical trial.
Breau, R.H., et al. (2024). JAMA Surgery.

Evaluating the safety and efficacy of a novel polysaccharide hemostatic system during surgery: a multicenter multispecialty prospective randomized controlled trial.
House, M.G., et al. (2024). Surgery Open Science.

Hospital policy of tranexamic acid to reduce transfusion in major non-cardiac surgery (TRACTION): protocol for a phase IV randomised controlled trial.
Houston, B.L., et al. (2024). BMJ Open.

The effect of perioperative sequential application of multiple doses of tranexamic acid on postoperative blood loss after PLIF: a prospective randomized controlled trial.
Dong, W., et al. (2024). International Journey of Surgery.

Tranexamic acid in patients undergoing liver resection: the HeLiX randomized clinical trial.
Karanicolas, P.J., et al. (2024). JAMA.

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