13 February 2025 (Thursday) - Transfusion Evidence LIbrary Update

The Transfusion Evidence Library sent its update today. Am I imagining it, or is the move against having blood transfusions gathering momentum?

Top article

Safety and efficacy of hypoxia-inducible factor-prolyl hydroxylase inhibitors vs. erythropoietin-stimulating agents in treating anemia in renal patients (with or without dialysis): a meta-analysis and systematic review.
Damarlapally, N., et al. (2023). Cureus.
PICO SUMMARY

 

Selected articles

Intravenous versus oral iron for anaemia among pregnant women in Nigeria (IVON): an open-label, randomised controlled trial.
Afolabi, B.B., et al. (2024). The Lancet Global Health.

Effect of minimization of early blood sampling losses among extremely premature neonates: a randomized clinical trial.
Balasubramanian, H., et al (2024). The Journal of Pediatrics.

Luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndromes (COMMANDS): primary analysis of a phase 3, open-label, randomised, controlled trial.
Della Porta, M.G., et al. (2024). The Lancet Haematology.

Effects of individualized anemia therapy on hemoglobin stability: a randomized controlled pilot trial in patients on hemodialysis.
Fuertinger, D.H., et al. (2024). Clinical Journal of the American Society of Nephrology. [Record in progress].

Standard of care versus octreotide in angiodysplasia-related bleeding (the OCEAN Study): a multicenter randomized controlled trial.
Goltstein, L.C.M.J., et al. (2024). Gastroenterology.

Effect of preoperative recombinant human erythropoietin on the need for blood transfusion and surgical outcomes in adult patients undergoing cardiac surgery: a systematic review and meta-analysis with trial sequential analysis.
Hakim, S.M., Ahmad, A.H.M., and Amer, A.M., (2024). Journal of Cardiothoracic and Vascular Anesthesia.

Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews.
Lewis,  S.R., et al. (2023). Cochrane Database of Systematic Reviews.

Darbepoetin alfa to reduce transfusion episodes in infants with haemolytic disease of the fetus and newborn who are treated with intrauterine transfusions in the Netherlands: an open-label, single-centre, phase 2, randomised, controlled trial.
Ree, I.M.C., et al. (2023). The Lancet Haematology.

Pharmacotherapy for reducing RBC transfusion for patients in the ICU: a systematic review and network meta-analysis. 
Yoshihiro, S., et al. (2024). Critical Care Medicine.