14 December 2024 (Saturday) - Transfusion Evidence Alert Update

The nice people at the Transfusion Evidence Alert sent their update today. Well actually they sent it a few days ago and it went into my junk email…
Again tranexamic acid features, and again there’s talk of keeping platelets in the fridge.

Top article 2024

 

Selected articles

Andexanet for factor Xa inhibitor-associated acute intracerebral hemorrhage.
Connolly, S.J., et al. (2024). The New England Journal of Medicine.

Meta-analysis and metaregression of the treatment effect of intravenous iron in iron-deficient heart failure.
Martens, P., et al. (2023). JACC: Heart Failure.

Prehospital tranexamic acid is associated with a survival benefit without an increase in complications: results of two harmonized randomized clinical trials.
Mazzei, M., et al. (2024). The Journal of Trauma and Acute Care Surgery.    

Two-year outcomes following a randomised platelet transfusion trial in preterm infants.
Moore, C.M., et al. (2023). Archives of Disease in Childhood. Fetal and Neonatal Edition.

Darbepoetin alfa to reduce transfusion episodes in infants with haemolytic disease of the fetus and newborn who are treated with intrauterine transfusions in the Netherlands: an open-label, single-centre, phase 2, randomised, controlled trial.
Ree, I.M.C., et al. (2023). The Lancet. Haematology.

Early cold stored platelet transfusion following severe injury: a randomized clinical trial.
Sperry, J.L., et al. (2024). Annals of Surgery.

Liberal or restrictive transfusion strategy in patients with traumatic brain injury.
Turgeon, A.F., et al. (2024). The New England Journal of Medicine.   

A cost-effectiveness analysis of early detection and bundled treatment of postpartum hemorrhage alongside the E-MOTIVE trial.
Williams, E.V., et al. (2024). Nature Medicine.  

Efficacy and safety of tranexamic acid in acute traumatic brain injury: a meta-analysis of randomized controlled trials.
Zhang, M. and Liu, T., (2024). The American Journal of Emergency Medicine.

 

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