26 November 2024 (Tuesday) - Transfusion Evidence Alert Update

The nice people at the Transfusion Evidence Alert sent their update today. There were two articles about the use of whole blood…

We used to issue that stuff years ago. Then red cell concentrates (packed cells) came in vogue. So much so that we would take the plasma off of units of whole blood to make red cell concentrates. Recently qualified colleagues have never seen a unit of whole blood.

 

But what was standard practice forty years ago and was largely dropped twenty years ago is now coming back…

ARTICLE OF THE MONTH Liberal versus restrictive transfusion strategies in acute myocardial infarction: a systematic review and comparative frequentist and Bayesian meta-analysis of randomized controlled trials. Braïk, R., et al. (2024). Annals of Intensive Care. PICO Summary available +++++

TOP ARTICLES Effect of perioperative erythropoietin on postoperative morbidity and mortality after cardiac surgery: a meta-analysis of randomized controlled trials. Abraham, D., et al. (2024). Anaesthesia, Critical Care & Pain Medicine. [Record in progress]. A randomized controlled trial comparing effectiveness of different fibrinogen preparations in restoring clot firmness. Baryshnikova, E., et al. (2024). Anesthesia and Analgesia. [Record in progress]. Early intervention of 5% albumin shown superior control of vascular integrity and function compared to ringer's lactate in hospitalized adult with grade I & II Dengue hemorrhagic fever: a multicenter randomized controlled trial in Indonesia. Bur, R., et al. (2024). Tropical Diseases, Travel Medicine and Vaccines. Mapping the landscape of machine learning models used for predicting transfusions in surgical procedures: a scoping review. Duranteau, O., et al. (2024). BMC Medical Informatics and Decision Making. Randomized controlled trials assessing continuous outcomes for the use of platelet-rich plasma in knee osteoarthritis are statistically fragile: a systematic review. Lameire, D.L., et al. (2024). Arthroscopy: The Journal of Arthroscopic & Related Surgery. [Record in progress]. Effect of preoperative autologous blood storage in major hepatectomy for perihilar malignancy: a randomized controlled trial. Onoe, S., et al. (2024). Annals of Surgery. [Record in progress]. Review of low titer group O whole blood (LTOWB) transfusion in initial resuscitation of pediatric trauma patients: assessing potential benefits. Park, S.M., et al. (2024). Journal of Pediatric Surgery. [Record in progress]. Does early transfusion of cold-stored whole blood reduce the need for component therapy in civilian trauma patients? a systematic review. Risha, M., et al. (2024). The Journal of Trauma and Acute Care Surgery. Assessment of hepatitis E virus transmission risks: a comprehensive review of cases among blood transfusion recipients and blood donors. Singson, S., et al. (2024). Infection Ecology & Epidemiology.