25 July 2023 (Tuesday) - Transfusion Evidence Library Update

 

The people at Transfusion Evidence Alert sent their update… far too much for my poor brain to process in one sitting. But yet again tranexamic acid features…

ARTICLE OF THE MONTH Prehospital tranexamic acid for severe trauma. Gruen, R.L., et al. (2023). The New England Journal of Medicine.  PICO Summary available +++++

TOP ARTICLES The impact of the Safe Delivery Application on knowledge and skills managing postpartum haemorrhage in a low resource setting: a cluster randomized controlled trial in West Wollega region, Ethiopia. Christiansen, A.H., et al. (2023). Reproductive Health.  Desmopressin for patients with spontaneous intracerebral haemorrhage taking antiplatelet drugs (DASH): a UK-based, phase 2, randomised, placebo-controlled, multicentre feasibility trial. Desborough, M.J.R., et al. (2023). The Lancet. Neurology.  Risk of thrombotic events in immune thrombocytopenia patients treated with thrombopoietic agents: a systematic review and meta-analysis. Dong, Y., et al. (2023). Thrombosis Journal.  Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures. Gibbs, V.N., et al. (2023). The Cochrane Database of Systematic Reviews. Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews. Lewis, S.R., et al. (2023). The Cochrane Database of Systematic Reviews. Factors that influence the administration of tranexamic acid (TXA) to trauma patients in prehospital settings: a systematic review. Nicholson, H., et al. (2023). BMJ Open. Eltrombopag for low-risk myelodysplastic syndromes with thrombocytopenia: interim results of a phase-II, randomized, placebo-controlled clinical trial (EQOL-MDS). Oliva, E. N., et al. (2023). Journal of Clinical Oncology. [Record in progress].  Efficacy and safety of luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndromes (COMMANDS): interim analysis of a phase 3, open-label, randomised controlled trial. Platzbecker, U., et al. (2023). Lancet. [Record in progress]. Men who have sex with men and risk for transfusion-transmissible infections in blood donors in Western countries: A systematic review update. Schroyens, N., et al. (2023). Vox Sanguinis. [Record in progress].