4 November 2022 (Friday) - Transfusion News Update

Threshold levels for transfusions, blood groups and COVID, creating rare antigens on red cells… as always the Transfusion News update is well worth having…

Transfusion Thresholds for Patients Receiving ECMO

November 2, 2022Venovenous extracorporeal membrane oxygenation (ECMO) can be used to help provide respiratory support to patients with severe acute respiratory distress syndrome (ARDS). Since hemoglobin is essential for oxygen delivery, the general practice has been to maintain hemoglobin levels in the normal range during ECMO to maximize oxygen delivery. [Read more]


ABO and Lewis Blood Groups Linked to Lower COVID-19 Susceptibility

October 26, 2022 Blood group O has been associated with decreased risk of SARS-CoV-2 infection in several small studies. In order to confirm these observations and determine if other blood groups are associated with SARS-CoV-2 infection, researchers in Denmark utilized data from the nationwide SCANDAT database. [Read more]


Pluripotent Stem Cell Gene Editing Provides Rare RBC Screening Cells

October 19, 2022Over 10 million of RBC units are transfused each year in the U.S. alone. Alloimmunization and hemolytic transfusion reactions pose a special challenge for those patients who are chronically transfused. While there are more than 350 RBC antigens identified, the Rh locus is highly immunogenic and has hundreds of variants owing to the large number of single-nucleotide polymorphisms, gene rearrangements and variable expression of the gene. [Read more]


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