26 October 2022 (Wednesday) - Transfusion Evidence Alert Update

The nice people at Transfusion Evidence Alert sent their update today… too much for my poor brain to take in on one sitting, but all good stuff…


A double-blind randomized placebo-controlled trial of albumin in patients with hepatic encephalopathy: HEAL study.Fagan, A., et al. (2022). Journal of Hepatology. [Record in progress].

Testing equivalence of two doses of intravenous iron to treat iron deficiency in pregnancy: A randomised controlled trial.Froessler, B., et al. (2022). BJOG: an International Journal of Obstetrics and Gynaecology. [Record in progress].

A randomized trial of blood donor iron repletion on red cell quality for transfusion and donor cognition and wellbeing.Hod, E.A., et al. (2022). Blood. [Record in progress].

Health-related quality of life after restrictive versus liberal RBC transfusion for cardiac surgery: Sub-study from a randomized clinical trial.Hu, R.T., et al. (2022). Transfusion.

Hydroxyurea (hydroxycarbamide) for sickle cell disease.Rankine-Mullings, A.E., and Nevitt, S.J., (2022). The Cochrane Database of Systematic Reviews.

Thrombelastography (TEG®6s) early amplitudes predict maximum amplitude in severely injured trauma patients.Vigstedt, M., et al. (2022). Scandinavian Journal of Clinical and Laboratory Investigation.

HLA Class II regulation of immune response in sickle cell disease patients: Susceptibility to red blood cell alloimmunization (systematic review and meta-analysis).Wong, K., Lai, W.K., and Jackson, D.E., (2022). Vox Sanguinis. [Record in progress].

Predictors of transfusion in trauma and their utility in the prehospital environment: a scoping reviewYin, G., et al. (2022). Prehospital Emergency Care. [Record in progress].

Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trial.Fish, M., et al. (2022). Intensive Care Medicine.


Thromboelastography-Guided Therapy Enhances Patient Blood Management in Cirrhotic Patients: A Meta-analysis Based on Randomized Controlled Trials.Hartmann, J., et al. (2022). Seminars in Thrombosis and Hemostasis. [Record in progress].PICO Summary available



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