29 March 2022 (Tuesday) - Transfusion Evidence Update

The nice people at the Transfusion Evidence Alert sent their monthly update today… and I had a look at the settings of my subscription with them. I couldn’t see how to change anything but they did have a link to a questionnaire about improving their services.

I asked for smaller updates but more frequently. They do swamp me with information…


Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.RECOVERY Collaborative Group. (2022). The Lancet.PICO Summary available



Surgical vs. Conservative Management for Lobar Intracerebral Hemorrhage, a Meta-Analysis of Randomized Controlled Trials.Akram, M.J., et al. (2021). Frontiers in Neurology.

Safety and efficacy of aprotinin versus tranexamic acid for reducing absolute blood loss and transfusion in pediatric patients undergoing craniosynostosis surgery: a randomized, double-blind, three-arm controlled trial.Ebrahim Soltani, Z., et al. (2022). Journal of Neurosurgery. [Record in progress]

Whole blood versus red cell concentrates for children with severe anaemia: a secondary analysis of the Transfusion and Treatment of African Children (TRACT) trial.George, E.C., et al. (2022). The Lancet. Global health.

Prehosptial low titer group o whole blood is feasible and safe: Results of a prospective randomized pilot trial.Guyette, F.X., et al. (2022). The Journal of Trauma and Acute Care Surgery. [Record in progress]

Pre-operative iron increases haemoglobin concentration before abdominal surgery: a systematic review and meta-analysis of randomized controlled trials.Meyer, J., et al. (2022). Scientific Reports.

Safety and Efficacy of Tranexamic Acid in Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis of Randomized Controlled Trials.Ren, J., et al. (2021). Frontiers in Neurology.

Comparison of early mortality between leukapheresis and non-leukapheresis in adult acute myeloid leukemia patients with hyperleukocytosis: a systematic review and meta-analysis.Rinaldi, I., Sutandyo, N., and Winston, K., (2022). Hematology.

Transfusion-Associated Delirium in Children: No Difference Between Short Storage Versus Standard Issue RBCs.Traube, C., et al. (2022). Critical Care Medicine.



Hyperimmune immunoglobulin for hospitalised patients with COVID-19 (ITAC): a double-blind, placebo-controlled, phase 3, randomised trial. (2022).The ITAC (INSIGHT 013) Study Group. The Lancet.


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