20 April 2022 (Wednesday) - Transfusion Evidence Alert Update

A few days ago I posted a link to an article saying that air ambulances zooming round brandishing bags of blood at trauma cases didn’t actually improve outcomes. Today’s missive from the nice people at Transfusion Evidence Alert also agreed with that sentiment.


Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trial.Crombie, N., et al. (2022). The Lancet. Haematology.PICO Summary available



Effect of washed versus unwashed red blood cells on transfusion-related immune responses in preterm newborns.Crawford, T.M., et al. (2022). Clinical & Translational Immunology.

The impact of red blood cell transfusion on mortality and treatment efficacy in patients treated with radiation: A systematic review.Deschner, M., et al. (2022). Clinical and Translational Radiation Oncology.

Efficacy of packed red blood cell transfusions based on weight versus formula in thalassemic children: An open-label randomized control trial.Kaur, M., et al. (2022). Transfusion.

Standard-Volume Plasma Exchange Improves Outcomes in Patients With Acute Liver Failure: A Randomized Controlled Trial.Maiwall, R., et al. (2022). Clinical Gastroenterology and Hepatology.

Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): a pilot randomized trial.Nishijima, D.K., et al. (2022). Academic Emergency Medicine.

Effects of perioperative erythropoietin administration on acute kidney injury and red blood cell transfusion in patients undergoing cardiac surgery: A systematic review and meta-analysis.Shin, H.J., et al. (2022). Medicine.

The effects of plasma exchange in patients with ANCA-associated vasculitis: an updated systematic review and meta-analysis.Walsh, M., et al. (2022). British Medical Journal.

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