11 March 2022 (Friday) - Transfusion News Update

The nice people at “Transfusion News” sent their update today. All very interesting, but I wish that science would make its mind up. Is convalescent plasma worth using or not? Opinion seems to be changing on a weekly basis…

Covid-19 Convalescent Plasma Neutralizes Variants of Concern Including Omicron

March 9, 2022Recent omicron variants of the SARS-CoV-2 virus have at least 32 changes in the spike protein relative to the original strain identified in Wuhan, rendering many monoclonal antibodies (e.g., sotrovimab and tixagevimab) developed against the Wuhan strain ineffective. Clinical trials, however, have shown that COVID-19 convalescent plasma (CCP) transfusions decrease the risk of hospitalization and mortality given to outpatients and immunosuppressed individuals with COVID-19, respectively. [Read More]


What is Liquid Plasma? with Chris Gresens

March 9, 2022 | BBGuy Podcast CE Episode! Plasma product names are confusing, but few are as misunderstood as Liquid Plasma. Dr. Chris Gresens explains why LP might be perfect for your transfusion service. [Listen Now]

Listen on Apple Podcast Get It on Google Podcasts Spotify


Enzymatic Treatment of Organ Allografts to Universal Blood Type O

March 2, 2022 Organ transplant recipients with group O blood type often have to wait at least twice as long as group A, B or AB recipients and have a 20% greater risk of mortality while on the transplant waitlist. Similar to RBCs, enzymatic removal of the terminal sugar epitope (α-galactose or N-acetyl-galactosamine) on A and B antigen oligosaccharides would convert these antigens to the universal group O blood type and expand the compatible organ donor pool. [Read More]


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