14 July 2021 (Wednesday) - Transfusion Evidence Alert Update

The nice people at the Transfusion Evidence Alert sent their update today. One of my better sources of CPD, but again too much for my poor brain to cope with in one sittng:

Top 10 new articles: June 2021

Each month, the NHS Blood and Transplant Systematic Review Initiative provides an overview of the most important new publications in transfusion medicine. All content is sourced from the Transfusion Evidence Library. COVID-19 publications are included in this alert.



Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial.
Lopes, R.D., et al. (2021). Lancet.
PICO Summary available



Heart Failure Hospitalization in Adults Receiving Hemodialysis and the Effect of Intravenous Iron Therapy.
Jhund, P.S., et al. (2021).JACC. Heart failure.

Plasma trial: Pilot randomized clinical trial to determine safety and efficacy of plasma transfusions.
Carson, J.L., et al. (2021). Transfusion. [Record in progress]

Use of electronic self-administered bleeding assessment tool in diagnosis of paediatric bleeding disorders.
Kaur, D., et al. (2021). Haemophilia [Record in progress]

Early Prehospital Tranexamic Acid Following Injury is Associated with a 30-day Survival Benefit: A Secondary Analysis of a Randomized Clinical Trial.
Li, S.R., et al. (2021). Annals of Surgery. [Record in progress]

Hemoglobin levels as a transfusion criterion in moderate to severe traumatic brain injury: a systematic review and meta-analysis.
Florez-Perdomo, W.A., et al. (2021). British Journal of Neurosurgery. [Record in progress]

Tranexamic acid given into wound reduces postoperative drainage, blood loss, and hospital stay in spinal surgeries: a meta-analysis.
Hui, S., et al. (2021). Journal of Orthopaedic Surgery and Research.

Contemporary Management and Prevention of Vaso-Occlusive Crises (VOCs) in Adults With Sickle Cell Disease.
Weaver, S.B., et al. (2021). Journal of Pharmacy Practice. [Record in progress]

Roxadustat for the treatment of anemia in patients with chronic kidney diseases: a meta-analysis.
Zhang, L., et al. (2021). Aging.



Gastrointestinal bleeding in covid-19 patients: A systematic review and meta-analysis.
Marasco, G., et al. (2021). Endoscopy.

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